Search Results - "de Sousa, Jayne Torres"
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Toxicological profile of the Hymenaea courbaril stem bark hydroalcoholic extract using in vitro bioassays and an alternative in vivo Caenorhabditis elegans model
Published in Journal of Toxicology and Environmental Health, Part A (17-09-2023)“…Hymenaea genus has been used in folk medicine in Brazil, but few studies investigated its toxicity profile. Thus, the aim of this study was to determine…”
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Photobiomodulation intervention improves oxidative, inflammatory, and morphological parameters of skeletal muscle in cirrhotic Wistar rats
Published in Lasers in medical science (01-04-2022)“…Photobiomodulation (PBM) might be an intervention method to mitigate sarcopenia in cirrhotic patients. Given the lack of research on this issue, the goal of…”
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Gamma-Decanolactone Alters the Expression of GluN2B, A1 Receptors, and COX-2 and Reduces DNA Damage in the PTZ-Induced Seizure Model After Subchronic Treatment in Mice
Published in Neurochemical research (01-08-2021)“…Gamma-decanolactone (GD) has been shown to reduce epileptic behavior in different models, inflammatory decreasing, oxidative stress, and genotoxic parameters…”
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4
Targeting thymidine phosphorylase inhibition in human colorectal cancer xenografts
Published in Biomedicine & pharmacotherapy (01-07-2021)“…Human thymidine phosphorylase (hTP) is overexpressed in several solid tumors and is commonly associated with aggressiveness and unfavorable prognosis…”
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Amantadine mitigates the cytotoxic and genotoxic effects of doxorubicin in SH-SY5Y cells and reduces its mutagenicity
Published in Toxicology in vitro (01-08-2024)“…Amantadine (AMA) is a useful drug in neuronal disorders, but few studies have been performed to access its toxicological profile. Conversely, doxorubicin (Dox)…”
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Morphine decreases cytotoxicity and mutagenicity of doxorubicin in vitro: Implications for cancer chemotherapy
Published in Chemico-biological interactions (01-09-2023)“…Morphine is the most common opioid analgesic administered to treat pain in patients undergoing cancer chemotherapy. This study aimed to evaluate the cytotoxic…”
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Toxicological aspects of Campomanesia xanthocarpa Berg. associated with its phytochemical profile
Published in Journal of Toxicology and Environmental Health, Part A (02-01-2019)“…Campomanesia xanthocarpa leaves are used as tea to treat diarrhea, inflammation, and hypercholesterolemia. Some pharmacological studies noted its beneficial…”
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Anti-hyperlipidemic effects of Campomanesia xanthocarpa aqueous extract and its modulation on oxidative stress and genomic instability in Wistar rats
Published in Journal of Toxicology and Environmental Health, Part A (17-09-2019)“…The use of natural products from herbs may be a therapeutic option in dyslipidemia treatment. Campomanesia xanthocarpa (Mart.) O. Berg (Myrtaceae) leaves have…”
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Gamma-Decanolactone Alters the Expression of GluN2B, A 1 Receptors, and COX-2 and Reduces DNA Damage in the PTZ-Induced Seizure Model After Subchronic Treatment in Mice
Published in Neurochemical research (21-05-2021)“…Gamma-decanolactone (GD) has been shown to reduce epileptic behavior in different models, inflammatory decreasing, oxidative stress, and genotoxic parameters…”
Get full text
Journal Article