Search Results - "de Sousa, Grasiely"
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Friedelane Triterpenes with Cytotoxic Activity from the Leaves of Maytenus quadrangulata (Celastraceae)
Published in Journal of the Brazilian Chemical Society (01-11-2022)“…Three new triterpenes, 3,4-seco-3,11β-epoxyfriedel-4(23)-en-3β-ol (1), friedelan- 3α,11β‑diol (2), 7β,26-epoxyfriedelan-3a,7a-diol (3), a mixture of two new…”
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Isolation and In Vitro Biological Evaluation of Triterpenes from Salacia grandifolia Leaves
Published in ACS omega (23-07-2024)“…Salacia grandifolia is naturally found in the Atlantic Forest regions of Brazil. Despite the pharmacological potential of plants from the Salacia genus,…”
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Caryopristimerin, the First Example of a Sesquiterpene-Triterpene Homo Diels‑Alder Adduct, and a New 29-nor-Friedelane from Roots of Salacia crassifolia
Published in Journal of the Brazilian Chemical Society (01-07-2019)“…Two new compounds, caryopristimerin and 2α,3α,22β-trihydroxy-21-oxo-29-nor-friedelan-24-oic acid, were isolated from the hexane/ethyl ether extract of Salacia…”
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Anti-angiogenic Activity of Polymeric Nanoparticles Loaded with Ursolic Acid
Published in Journal of drug targeting (04-10-2024)“…Ursolic acid is an abundant natural product and has shown great promise for treating diseases related to the appearance of new blood vessels. However, its…”
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Synthesis and Cytotoxic Activity of Friedelinyl Esters
Published in Chemistry & biodiversity (01-09-2024)“…Commonly isolated from plants of Celastraceae family, pentacyclic triterpenoids have a broad spectrum of biological activities, such as antitumor,…”
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Activity of extracts and terpenoids from Tontelea micrantha (Mart. ex Schult.) A.C.Sm. (Celastraceae) against pathogenic bacteria
Published in Natural product research (08-02-2024)“…The pharmacological properties of plant extracts and phytochemicals, such as flavonoids and terpenoids, remain of great interest. In this work, the effect of…”
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Chemical Composition of Magonia pubescens Essential Oils and Gamma‐Radiation Effects on Its Constituents and Cytotoxic Activity in Leukemia and Breast Cancer Model
Published in Chemistry & biodiversity (01-06-2021)“…Magonia pubescens A. St.‐Hil. is a Brazilian species often used in ethnopharmacology for wound and pain healing and seborrhea treatment. For the first time,…”
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Virucidal antiviral activity of Maytenus quadrangulata extract against Mayaro virus: Evidence for the presence of catechins
Published in Journal of ethnopharmacology (15-07-2023)“…Mayaro virus (MAYV) is an arbovirus endemic to the Amazon region, which comprises the states of the North and Midwest region of Brazil and encompasses the…”
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Flavonoids and Triterpenoids Isolated From the Ethyl Acetate Extract of M. quadrangulata Leaves
Published in Chemistry & biodiversity (01-07-2024)“…The new flavonoid (−)‐4’‐O‐methylepicatechin 5‐O‐β‐D‐glucopyranoside (1), along with four known triterpenes (2‐5), a steroid (6), and a flavonoid (7) were…”
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Maytenus robusta Reissek, a medicinal plant popularly used to treat digestive diseases, promotes ameliorative effects in colon and liver of mice exposed to dextran sulfate sodium
Published in Journal of ethnopharmacology (28-10-2020)“…Maytenus robusta Reissek (Celesteraceae), popularly named as cafezinho do mato or coração de bugre, is employed to treat inflammatory digestive diseases in the…”
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Chemodiversity of Essential Oils from Nine Species of Celastraceae
Published in Chemistry & biodiversity (01-05-2020)“…Extracts and compounds obtained from several species of Celastraceae family are reported as potential sources of drugs due to their diverse pharmacological…”
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Triterpenes from leaves of Cheiloclinium cognatum and their in vivo antiangiogenic activity
Published in Magnetic resonance in chemistry (01-05-2018)Get full text
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Evaluation of Cytotoxicity and Antifungal Activity of Friedelanes from Salacia elliptica Roots
Published in Chemistry & biodiversity (01-10-2023)“…Plants from Salacia genus are used in traditional medicine for a wide range of diseases. Previous studies reported bioactive pentacyclic triterpenoids from S…”
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Chemical constituents of Salacia elliptica (Celastraceae)
Published in Química nova (2010)“…The chemical investigation of Salacia elliptica allowed to the isolation of 20 constituents: two polyols, one xanthone, a mixture of long chain hydrocarbons,…”
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Mucilaginous Secretions in the Xylem and Leaf Apoplast of the Swamp Palm Mauritia flexuosa L.f. (Arecaceae)
Published in Microscopy and microanalysis (01-06-2020)“…Mauritia flexuosa palms inhabit wetland environments in the dry, seasonal Brazilian savanna (Cerrado) and produce mucilaginous secretions in the stem and…”
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Pentacyclic Triterpenes from Branches of Maytenus robusta and in vitro Cytotoxic Property Against 4T1 Cancer Cells
Published in Journal of the Brazilian Chemical Society (01-08-2014)“…Two new friedelane-type compounds 1 and 2 and five known pentacyclic triterpenes were isolated from branches of Maytenus robusta. Their structures were…”
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Flavonol triglycosides of leaves from Maytenus robusta with acetylcholinesterase inhibition
Published in Phytochemistry letters (01-03-2017)Get full text
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Laticifer ontogenesis and the chemical constituents of Marsdenia zehntneri (Apocynaceae) latex in a semiarid environment
Published in Planta (01-01-2023)“…Main conclusion Anastomosed laticifers with intrusive growth produce latex containing methyl comate and betulin with economic and ecological value in arid…”
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New Eugenol Glucoside-based Derivative Shows Fungistatic and Fungicidal Activity against Opportunistic Candida glabrata
Published in Chemical biology & drug design (01-01-2016)“…A new series of glucosides modified in their saccharide units were synthesized, evaluated against Candida sp., and compared to prototype 1, an eugenol…”
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