Search Results - "de Solis, Alain J"

NPY mediates the rapid feeding and glucose metabolism regulatory functions of AgRP neurons by Engström Ruud, Linda, Pereira, Mafalda M. A., de Solis, Alain J., Fenselau, Henning, Brüning, Jens C.

“…Activation of Agouti-Related Peptide (AgRP)-expressing neurons promotes feeding and insulin resistance. Here, we examine the contribution of neuropeptide Y…”
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Age-associated decrease of SIRT1 expression in rat hippocampus: prevention by late onset caloric restriction by Quintas, Ana, de Solís, Alain J, Díez-Guerra, F Javier, Carrascosa, José M, Bogónez, Elena

“…We have studied the effect of aging and late onset caloric restriction (CR) on the expression of SIRT1 in hippocampus and cerebral cortex of the rat…”
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New roles for dopamine D2 and D3 receptors in pancreatic beta cell insulin secretion by Farino, Zachary J., Morgenstern, Travis J., Maffei, Antonella, Quick, Matthias, De Solis, Alain J., Wiriyasermkul, Pattama, Freyberg, Robin J., Aslanoglou, Despoina, Sorisio, Denise, Inbar, Benjamin P., Free, R. Benjamin, Donthamsetti, Prashant, Mosharov, Eugene V., Kellendonk, Christoph, Schwartz, Gary J., Sibley, David R., Schmauss, Claudia, Zeltser, Lori M., Moore, Holly, Harris, Paul E., Javitch, Jonathan A., Freyberg, Zachary

“…Although long-studied in the central nervous system, there is increasing evidence that dopamine (DA) has important roles in the periphery including in…”
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HypoMap—a unified single-cell gene expression atlas of the murine hypothalamus by Steuernagel, Lukas, Lam, Brian Y. H., Klemm, Paul, Dowsett, Georgina K. C., Bauder, Corinna A., Tadross, John A., Hitschfeld, Tamara Sotelo, del Rio Martin, Almudena, Chen, Weiyi, de Solis, Alain J., Fenselau, Henning, Davidsen, Peter, Cimino, Irene, Kohnke, Sara N., Rimmington, Debra, Coll, Anthony P., Beyer, Andreas, Yeo, Giles S. H., Brüning, Jens C.

“…The hypothalamus plays a key role in coordinating fundamental body functions. Despite recent progress in single-cell technologies, a unified catalog and…”
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Impairment of skeletal muscle insulin action with aging in Wistar rats: Role of leptin and caloric restriction by De Solís, Alain J., Fernández-Agulló, Teresa, García-SanFrutos, Miriam, Pérez-Pardo, Paula, Bogónez, Elena, Andrés, Antonio, Ros, Manuel, Carrascosa, José M.

“…► We studied muscle insulin resistance along aging and the role of hyperleptinemia. ► Insulin sensitivity decreases with aging and is restored by caloric…”
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Dopamine-inhibited POMCDrd2+ neurons in the ARC acutely regulate feeding and body temperature by Gaziano, Isabella, Corneliussen, Svenja, Biglari, Nasim, Neuhaus, René, Shen, Linyan, Sotelo-Hitschfeld, Tamara, Klemm, Paul, Steuernagel, Lukas, De Solis, Alain J, Chen, Weiyi, Wunderlich, F Thomas, Kloppenburg, Peter, Brüning, Jens C

“…Dopamine acts on neurons in the arcuate nucleus (ARC) of the hypothalamus, which controls homeostatic feeding responses. Here we demonstrate a differential…”
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Effects of Moderate Chronic Food Restriction on the Development of Postprandial Dyslipidemia with Ageing by Fernández, Alejandro, Mazuecos, Lorena, Pintado, Cristina, Rubio, Blanca, López, Virginia, de Solís, Alain J, Rodríguez, María, Andrés, Antonio, Gallardo, Nilda

“…Ageing is a major risk factor for the development of metabolic disorders linked to dyslipidemia, usually accompanied by increased adiposity. The goal of this…”
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Impaired Central Insulin Response in Aged Wistar Rats: Role of Adiposity by García-San Frutos, Miriam, Fernández-Agulló, Teresa, De Solís, Alain J, Andrés, Antonio, Arribas, Carmen, Carrascosa, José M, Ros, Manuel

“…Insulin, like leptin, is considered as a lipostatic signal acting at a central level. Aging and age-associated adiposity have been related to the development…”
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Development of insulin resistance during aging: involvement of central processes and role of adipokines by Carrascosa, José M, Andrés, Antonio, Ros, Manuel, Bogónez, Elena, Arribas, Carmen, Fernández-Agulló, Teresa, De Solís, Alain J, Gallardo, Nilda, Martínez, Carmen

“…Aging in mammals associates with the development of peripheral insulin resistance. Additionally, adiposity usually increases with aging and this could play a…”
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Developmental switch of leptin signaling in arcuate nucleus neurons by Baquero, Arian F, de Solis, Alain J, Lindsley, Sarah R, Kirigiti, Melissa A, Smith, M Susan, Cowley, Michael A, Zeltser, Lori M, Grove, Kevin L

“…Leptin is well known for its role in the regulation of energy homeostasis in adults, a mechanism that at least partially results from the inhibition of the…”
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Reciprocal activity of AgRP and POMC neurons governs coordinated control of feeding and metabolism by De Solis, Alain J., Del Río-Martín, Almudena, Radermacher, Jan, Chen, Weiyi, Steuernagel, Lukas, Bauder, Corinna A., Eggersmann, Fynn R., Morgan, Donald A., Cremer, Anna-Lena, Sué, Michael, Germer, Maximilian, Kukat, Christian, Vollmar, Stefan, Backes, Heiko, Rahmouni, Kamal, Kloppenburg, Peter, Brüning, Jens C.

“…Agouti-related peptide (AgRP)-expressing and proopiomelanocortin (POMC)-expressing neurons reciprocally regulate food intake. Here, we combine non-interacting…”
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Ciliary gene RPGRIP1L is required for hypothalamic arcuate neuron development by Wang, Liheng, De Solis, Alain J, Goffer, Yossef, Birkenbach, Kathryn E, Engle, Staci E, Tanis, Ross, Levenson, Jacob M, Li, Xueting, Rausch, Richard, Purohit, Manika, Lee, Jen-Yi, Tan, Jerica, De Rosa, Maria Caterina, Doege, Claudia A, Aaron, Holly L, Martins, Gabriela J, Brüning, Jens C, Egli, Dieter, Costa, Rui, Berbari, Nicolas, Leibel, Rudolph L, Stratigopoulos, George

“…Intronic polymorphisms in the α-ketoglutarate-dependent dioxygenase gene (FTO) that are highly associated with increased body weight have been implicated in…”
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Alkalinization potentiates vascular calcium deposition in an uremic milieu by de Solis, Alain J, González-Pacheco, Francisco R, Deudero, Juan J P, Neria, Fernando, Albalate, Marta, Petkov, Vladimir, Susanibar, Luis, Fernandez-Sanchez, Ruth, Calabia, Olalla, Ortiz, Alberto, Caramelo, Carlos

“…Vascular calcification is a serious complication of chronic kidney disease. Acid-base balance is a relevant, albeit somewhat forgotten factor in the regulation…”
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Mechanisms of endothelial cell protection by blockade of the JAK2 pathway by Neria, Fernando, Caramelo, Carlos, Peinado, Héctor, González-Pacheco, Francisco R, Deudero, Juan J P, de Solis, Alain J, Fernández-Sánchez, Ruth, Peñate, Silvia, Cano, Amparo, Castilla, María Angeles

“…Inhibition of the JAK2/STAT pathway has been implicated recently in cytoprotective mechanisms in both vascular smooth muscle cells and astrocytes. The advent…”
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Response to hypoxia. A systemic mechanism based on the control of gene expression by Caramelo, Carlos, Peña Deudero, Juan J, Castilla, Angeles, Justo, Soledad, De Solis, Alain J, Neria, Fernando, Peñate, Silvia, Gonzalez-Pacheco, Francisco R

“…New, critically important data have been recently generated about the response to hypoxia. This response can be schematized in three main systems or functions,…”
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New roles for dopamine D.sub.2 and D.sub.3 receptors in pancreatic beta cell insulin secretion by Farino, Zachary J, Morgenstern, Travis J, Maffei, Antonella, Quick, Matthias, De Solis, Alain J, Wiriyasermkul, Pattama, Freyberg, Robin J

“…Although long-studied in the central nervous system, there is increasing evidence that dopamine (DA) has important roles in the periphery including in…”
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Age-associated decrease of SIRT1 expression in rat hippocampus by Quintas, Ana, de Solís, Alain J., Díez-Guerra, F. Javier, Carrascosa, José M., Bogónez, Elena

“…We have studied the effect of aging and late onset caloric restriction (CR) on the expression of SIRT1 in hippocampus and cerebral cortex of the rat…”
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EFFECTS OF CHRONIC ACARBOSE TREATMENT ON ADIPOCYTE INSULIN RESPONSIVENESS, SERUM LEVELS OF LEPTIN AND ADIPONECTIN AND HYPOTHALAMIC NPY EXPRESSION IN OBESE DIABETIC WISTAR RATS by Pérez, Coralia, Fernández-Agulló, Teresa, De Solís, Alain J, Ros, Manuel, Andrés, Antonio, Carrascosa, José M

“…SUMMARY 1 Inhibitors of intestinal glucosidases have been shown to improve glycaemic control in diabetic and obese humans and animals. In the present study, we…”
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New roles for dopamine D 2 and D 3 receptors in pancreatic beta cell insulin secretion by Farino, Zachary J, Morgenstern, Travis J, Maffei, Antonella, Quick, Matthias, De Solis, Alain J, Wiriyasermkul, Pattama, Freyberg, Robin J, Aslanoglou, Despoina, Sorisio, Denise, Inbar, Benjamin P, Free, R Benjamin, Donthamsetti, Prashant, Mosharov, Eugene V, Kellendonk, Christoph, Schwartz, Gary J, Sibley, David R, Schmauss, Claudia, Zeltser, Lori M, Moore, Holly, Harris, Paul E, Javitch, Jonathan A, Freyberg, Zachary

“…Although long-studied in the central nervous system, there is increasing evidence that dopamine (DA) has important roles in the periphery including in…”
Get full text