Search Results - "de Siqueira Patriota, Leydianne Leite"
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The Anxiolytic Activity of Schinus terebinthifolia Leaf Lectin (SteLL) Is Dependent on Monoaminergic Signaling although Independent of the Carbohydrate-Binding Domain of the Lectin
Published in Pharmaceuticals (Basel, Switzerland) (07-11-2022)“…The potential of plant lectins (carbohydrate-binding proteins) for the treatment of neurological disorders such as anxiety and depression has started to be…”
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Microgramma vacciniifolia Frond Lectin: In Vitro Anti-leishmanial Activity and Immunomodulatory Effects Against Internalized Amastigote Forms of Leishmania amazonensis
Published in Acta parasitologica (01-12-2023)“…Purpose The treatment of leishmaniasis, an anthropozoonosis caused by Leishmania protozoa, is limited by factors, such as adverse effects, toxicity, and…”
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Effects of Lectins from Alpinia purpurata Inflorescence (ApuL) and Schinus terebinthifolia Leaf (SteLL) on Human Leukemic Cell Lines and Mesenchymal Stem Cells
Published in Macromol (01-06-2023)“…Lectins (carbohydrate-binding proteins) are able to distinguish different patterns of glycosylation on cell surfaces. This study investigated the effects of…”
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Purification, characterization, and immunomodulatory activity of a lectin from the seeds of horse chestnut (Aesculus hippocastanum L.)
Published in Current research in biotechnology (2022)“…[Display omitted] •A thermostable and multifunctional protein (AhSL) was purified from A. hippocastamum seeds.•AhSL showed lectin and trypsin inhibitor…”
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A Trypsin Inhibitor from Moringa oleifera Flowers Modulates the Immune Response In Vitro of Trypanosoma cruzi-Infected Human Cells
Published in Antibiotics (Basel) (14-08-2020)“…Trypanosoma cruzi causes the lethal Chagas disease, which is endemic in Latin America. Flowers of Moringa oleifera (Moringaceae) express a trypsin inhibitor…”
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The lectin from Schinus terebinthifolia leaf (SteLL) reduces immobility of mice on the tail suspension test dependent on the monoaminergic and nitric oxide signaling
Published in Neuroscience letters (28-03-2023)“…•Natural products have been studied as antidepressant agents aiming to make available new options for the daily basis treatment of those psychological…”
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Assessment of acute toxicity, genotoxicity, and anti-inflammatory activity of SteLL, a lectin from Schinus terebinthifolia Raddi. Leaves, in mice
Published in Journal of ethnopharmacology (28-10-2024)“…Schinus terebinthifolia Raddi (Anacardiaceae), known as Brazilian pepper tree, stands out as a medicinal plant widely used in traditional medicine. The leaves…”
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Acute oral toxicity and genotoxicity assessment of the essential oil from Croton pulegiodorus Baill (Euphorbiaceae) leaves in mice
Published in Toxicon (Oxford) (28-11-2024)“…Essential oils obtained from Croton pulegiodorus leaf are renowned for their biological activities; however, data on their toxicity are limited. Therefore,…”
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Antitumor activity of Moringa oleifera (drumstick tree) flower trypsin inhibitor (MoFTI) in sarcoma 180-bearing mice
Published in Food and chemical toxicology (01-11-2020)“…The plant Moringa oleifera is used as food and medicine. M. oleifera flowers are source of protein, fiber, and antioxidants, and are used to treat inflammation…”
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Inhibition of Carrageenan-Induced Acute Inflammation in Mice by the Microgramma vacciniifolia Frond Lectin (MvFL)
Published in Polymers (15-04-2022)“…Most anti-inflammatory drugs used nowadays have an excessive cost and their prolonged use has been connected with several injurious effects. Thus, the search…”
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Saline Extract from Moringa oleifera Leaves Has Antidepressant and Anxiolytic Effects in Mouse Models
Published in Nutraceuticals (04-02-2024)“…Plant extracts can be therapeutic alternatives for depression and anxiety. However, some plant-derived preparations can also be toxic. Moringa oleifera leaves…”
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The anxiolytic-like activity of water-soluble Moringa oleifera Lam. lectin is mediated via serotoninergic, noradrenergic, and dopaminergic neurotransmission
Published in Brain disorders (01-03-2023)“…•The water-soluble lectin from Moringa oleifera seeds (WSMoL) showed anxiolytic effect.•WSMoL also displayed anti-anxiogenic action when co-administrated with…”
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Schinus terebinthifolia leaf lectin (SteLL) is an immunomodulatory agent by altering cytokine release by mice splenocytes
Published in 3 Biotech (01-04-2020)“…Schinus terebinthifolia leaf lectin (SteLL) was reported to be an antimicrobial and antitumor agent. In this work, we evaluated the immunomodulatory activity…”
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Microgramma vacciniifolia frond lectin (MvFL) exhibits antitumor activity against sarcoma 180 in mice
Published in Phytomedicine Plus : International journal of phytotherapy and phytopharmacology (01-02-2021)“…•MvFL induced apoptosis and necrosis in sarcoma 180 cells in vitro.•MvFL reduced tumor weight, increased leukocyte infiltrate, and presented anti-angiogenic…”
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Moringa oleifera Lam. seed lectin (WSMoL) reduces chronic stress-induced anxiety and depression in mice by lessening inflammation and balancing brain chemicals
Published in Behavioural brain research (04-02-2025)“…Phyto-based treatments for anxiety and depression are gaining attention. The efficacy of the water-soluble Moringa oleifera seed lectin (WSMoL) in reducing…”
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Toxicity and antitumor activity of the water-soluble lectin from Moringa oleifera Lam. Seeds (WSMoL) in sarcoma 180-bearing mice
Published in Toxicon (Oxford) (01-10-2023)“…WSMoL, a water-soluble lectin from the seeds of Moringa oleifera, present several biological activities. This work aimed to evaluated the toxicity and…”
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Schinus terebinthifolia leaf lectin has central and peripheral antinociceptive action mediated by its carbohydrate-recognition domain and delta-opioid receptors
Published in Journal of ethnopharmacology (30-01-2023)“…Preparations from the bark and leaves of Schinus terebinthifolia Raddi are commonly used to treat toothaches and sore throats. The use of medications based on…”
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CasuL: A new lectin isolated from Calliandra surinamensis leaf pinnulae with cytotoxicity to cancer cells, antimicrobial activity and antibiofilm effect
Published in International journal of biological macromolecules (01-05-2017)“…•CasuL is an acidic (pI 5.82) and oligomeric protein of approximately 48kDa.•CasuL did not undergo unfolding when heated up to100°C.•CasuL was cytotoxic to…”
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Quantum dots conjugated to lectins from Schinus terebinthifolia leaves (SteLL) and Punica granatum sarcotesta (PgTeL) as potential fluorescent nanotools for investigating Cryptococcus neoformans
Published in International journal of biological macromolecules (01-12-2021)“…This study reports the development of conjugates based on quantum dots (QD)s and lectins from Schinus terebinthifolia leaves (SteLL) and Punica granatum…”
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Evaluation of antitumor activity and toxicity of Schinus terebinthifolia leaf extract and lectin (SteLL) in sarcoma 180-bearing mice
Published in Journal of ethnopharmacology (06-04-2019)“…Schinus terebinthifolia Raddi is a plant broadly used in folk medicine and the use of its leaf extract as an antitumor agent has been reported. To evaluate the…”
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