Search Results - "de Silva, Heshani"

Grapevine red blotch virus C2 and V2 are suppressors of post-transcriptional gene silencing by Weligodage, Heshani De Silva, Jin, Gan, Kaur, Maninderjeet, Rock, Christopher D., Sunitha, Sukumaran

“…Grapevine red blotch virus (GRBV) is the causative agent of grapevine red blotch disease (GRBD) which is one of the major threats faced by grapevine industry…”
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Identification of a nonkinase target mediating cytotoxicity of novel kinase inhibitors by Ross-Macdonald, Petra, de Silva, Heshani, Guo, Qi, Xiao, Hong, Hung, Chen-Yi, Penhallow, Becky, Markwalder, Jay, He, Liqi, Attar, Ricardo M, Lin, Tai-an, Seitz, Steven, Tilford, Charles, Wardwell-Swanson, Judith, Jackson, Donald

“…In developing inhibitors of the LIM kinases, the initial lead molecules combined potent target inhibition with potent cytotoxic activity. However, as…”
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Should male doctors in Sri Lanka wear a necktie to be recognized and respected? by Abeysundara, Prabath K, Nishad, Nilanga, Balendran, Karthiha, Pabasara, Manod, Bandara, Poornima K, Perera, Narmada M, De Silva, Heshani, De Silva, Shamila, Umakanth, Maheswaran, Wijesinghe, Prasantha

“…European cultural norms have influenced physicians' attire in Sri Lanka. The necktie is one such item of clothing which is worn to be recognized and respected…”
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Transcriptional profiling of the dose response: a more powerful approach for characterizing drug activities by Ji, Rui-Ru, de Silva, Heshani, Jin, Yisheng, Bruccoleri, Robert E, Cao, Jian, He, Aiqing, Huang, Wenjun, Kayne, Paul S, Neuhaus, Isaac M, Ott, Karl-Heinz, Penhallow, Becky, Cockett, Mark I, Neubauer, Michael G, Siemers, Nathan O, Ross-Macdonald, Petra

“…The dose response curve is the gold standard for measuring the effect of a drug treatment, but is rarely used in genomic scale transcriptional profiling due to…”
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Biochemical and transcriptional profiling to triage additional activities in a series of IGF-1R/IR inhibitors by Ross-Macdonald, Petra, de Silva, Heshani, Patel, Vishal, Truong, Amy, He, Aiqing, Neuhaus, Isaac, Tilford, Charles, Ji, RuiRu, Siemers, Nathan, Greer, Ann, Carboni, Joan, Gottardis, Marco, Menard, Krista, Lee, Frank, Dodier, Marco, Frennesson, David, Sampognaro, Anthony, Saulnier, Mark, Trainor, George, Vyas, Dolatrai, Zimmermann, Kurt, Wittman, Mark

“…Therapeutic development of a targeted agent involves a series of decisions over additional activities that may be ignored, eliminated or pursued. This paper…”
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Attitudes toward ambiguous situations resemble the domain-specificity of attitudes toward risk by Shou, Yiyun, De Silva, Heshani Samantha, Olney, Joel

“…Individual differences in attitudes toward uncertainty have long been studied as a general propensity in how people respond to uncertain situations. However,…”
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184 Prevalence and clinical outcomes of thoracic aortic disease detected within a UK lung screening programme: A 5 year follow-up study by Kimani, Linda, Hawes, David, De Silva, Heshani, Goodley, Patrick, Booton, Richard, Waterworth, Paul, Balata, Haval

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A Landscape of Pharmacogenomic Interactions in Cancer by Iorio, Francesco, Knijnenburg, Theo A., Vis, Daniel J., Bignell, Graham R., Menden, Michael P., Schubert, Michael, Aben, Nanne, Gonçalves, Emanuel, Barthorpe, Syd, Lightfoot, Howard, Cokelaer, Thomas, Greninger, Patricia, van Dyk, Ewald, Chang, Han, de Silva, Heshani, Heyn, Holger, Deng, Xianming, Egan, Regina K., Liu, Qingsong, Mironenko, Tatiana, Mitropoulos, Xeni, Richardson, Laura, Wang, Jinhua, Zhang, Tinghu, Moran, Sebastian, Sayols, Sergi, Soleimani, Maryam, Tamborero, David, Lopez-Bigas, Nuria, Ross-Macdonald, Petra, Esteller, Manel, Gray, Nathanael S., Haber, Daniel A., Stratton, Michael R., Benes, Cyril H., Wessels, Lodewyk F.A., Saez-Rodriguez, Julio, McDermott, Ultan, Garnett, Mathew J.

“…Systematic studies of cancer genomes have provided unprecedented insights into the molecular nature of cancer. Using this information to guide the development…”
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Police-reported family violence: are there differences amongst South Asian Australians and Australian-born Australians? by De Silva, Heshani S., Shepherd, Stephane M., McEwan, Troy E.

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Hidden numbers, hidden people: Family violence among South Asian Australians by De Silva, Heshani Samantha, Shepherd, Stephane M., McEwan, Troy E.

“…International research suggests that migrants face additional challenges that may heighten their risk of experiencing family violence (FV). South Asians are…”
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16 The impact of implanting ctDNA testing on day 0 of the lung cancer pathway in patients with advanced stage disease in Manchester by Ghoshal, Avik, Goodley, Patrick, Ahuja, Gaurav, De Silva, Heshani, Alsaaty, Alaa, Watson, Charlotte, Booton, Richard, Balata, Haval, Crosbie, Phil, Sinnott, Nicola, Chung, Jonathan Hiu Nian, Craig, Christopher, Krebs, Matthew, Sutcliffe, Anthony, Evison, Matthew

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Validation of the Lung Immune Prognostic Index (LIPI) as a prognostic biomarker in metastatic renal cell carcinoma by Carril-Ajuria, Lucia, Lavaud, Pernelle, Dalban, Cecile, Negrier, Sylvie, Gravis, Gwénaëlle, Motzer, Robert J., Chevreau, Christine, Tannir, Nizar M., Oudard, Stéphane, McDermott, David F., Laguerre, Brigitte, Hammers, Hans J., Barthelemy, Philippe, Plimack, Elizabeth R., Borchiellini, Delphine, Gross-Goupil, Marine, Jiang, Ruiyun, Lee, Chung-Wei, de Silva, Heshani, Rini, Brian I., Escudier, Bernard, Albigès, Laurence

“…The Lung Immune Prognostic Index (LIPI) is associated with immune checkpoint inhibitors (ICI) outcomes across different solid tumors, particularly in non-small…”
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A landscape of pharmacogenomic interactions in cancer by Iorio, Francesco, Knijnenburg, Theo A, Vis, Daniel J, Bignell, Graham, Menden, Michael P, Schubert, Michael, Aben, Nanne, Gonçalves, Emanuel, Barthorpe, Syd, Lightfoot, Howard, Cokelae, Thomas, Greninger, Patricia, Dyk, Ewald van, Chang, Han, Silva, Heshani de, Heyn, Holger, Deng, Xianming, Egan, Regina K, Liu, Qingsong, Mironenko, Tatiana, Mitropoulos, Xeni, Richardson, Laura, Wang, Jinhua, Zhang, Tinghu, Moran, Sebastian, Sayols, Sergi, Soleimani, Maryam, Tamborero, David, López Bigas, Núria, Ross-Macdonald, Petra, Esteller, Manel, Gray, Nathanael S, Haber, Daniel A, Stratton, Michael R, Benes, Cyril H, Wessels, Lodewyk F.A, Saez-Rodriguez, Julia, McDermott, Ultan, Garnett, Mathew J

“…Systematic studies of cancer genomes have provided unprecedented insights into the molecular nature of cancer. Using this information to guide the development…”
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Chemical genetics identifies Rab geranylgeranyl transferase as an apoptotic target of farnesyl transferase inhibitors by Lackner, Mark R., Kindt, Rachel M., Carroll, Pamela M., Brown, Katherine, Cancilla, Michael R., Chen, Changyou, de Silva, Heshani, Franke, Yvonne, Guan, Bo, Heuer, Tim, Hung, Tak, Keegan, Kevin, Lee, Jae Moon, Manne, Veeraswamy, O’Brien, Carol, Parry, Dianne, Perez-Villar, Juan J., Reddy, Rajashekar K., Xiao, Hong, Zhan, Hangjun, Cockett, Mark, Plowman, Greg, Fitzgerald, Kevin, Costa, Michael, Ross-Macdonald, Petra

“…A chemical genetics approach identified a cellular target of several proapoptotic farnesyl transferase inhibitors (FTIs). Treatment with these FTIs caused…”
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Transcriptional Profiling of the Dose Response: A More Powerful Approach for Characterizing Drug Activities: e1000512 by Ji, Rui-Ru, Silva, Heshani de, Jin, Yisheng, Bruccoleri, Robert E, Cao, Jian, He, Aiqing, Huang, Wenjun, Kayne, Paul S, Neuhaus, Isaac M, Ott, Karl-Heinz, Penhallow, Becky, Cockett, Mark I, Neubauer, Michael G, Siemers, Nathan O, Ross-Macdonald, Petra

“…The dose response curve is the gold standard for measuring the effect of a drug treatment, but is rarely used in genomic scale transcriptional profiling due to…”
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Identification of a Novel Stress Activated Kinase in Kidney and Heart by De Silva, Heshani, Cioffi, Catherine, Yin, Tinggui, Sandhu, Gulzar, Webb, Randy L., Whelan, James

“…We have previously described the patterns of stress kinase activation in rat kidney and heart in response to ischemia/reperfusion (Yin et al., 1997,J. Biol…”
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Identification of a novel stress kinase activated by ischemia/reperfusion in the heart and kidney by Whelan, James, Cioffi, Catherine, De Silva, Heshani, Sandhu, Gulzar, Webb, Randy

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Biochemical and transcriptional profiling to triage additional activities in a series of IGF-1R/IR inhibitors: The Chemistry Biology Interface by ROSS-MACDONALD, Petra, DE SILVA, Heshani, CARBONI, Joan, GOTTARDIS, Marco, MENARD, Krista, LEE, Frank, DODIER, Marco, FRENNESSON, David, SAMPOGNARO, Anthony, SAULNIER, Mark, TRAINOR, George, VYAS, Dolatrai, PATEL, Vishal, ZIMMERMANN, Kurt, WITTMAN, Mark, TRUONG, Amy, AIQING HE, NEUHAUS, Isaac, TILFOR, Charles, RUIRUJI, SIEMERS, Nathan, GREER, Ann

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