Search Results - "de Septenville, Anne Langlois"
-
1
Immunoglobulin gene analysis in chronic lymphocytic leukemia in the era of next generation sequencing
Published in Leukemia (01-10-2020)“…Twenty years after landmark publications, there is a consensus that the somatic hypermutation (SHM) status of the clonotypic immunoglobulin heavy variable…”
Get full text
Journal Article -
2
The helicases DinG, Rep and UvrD cooperate to promote replication across transcription units in vivo
Published in The EMBO journal (06-01-2010)“…How living cells deal with head‐on collisions of the replication and transcription complexes has been debated for a long time. Even in the widely studied model…”
Get full text
Journal Article -
3
A multi-objective based clustering for inferring BCR clonal lineages from high-throughput B cell repertoire data
Published in PLoS computational biology (29-08-2022)“…The adaptive B cell response is driven by the expansion, somatic hypermutation, and selection of B cell clonal lineages. A high number of clonal lineages in a…”
Get full text
Journal Article -
4
ViCloD, an interactive web tool for visualizing B cell repertoires and analyzing intraclonal diversities: application to human B-cell tumors
Published in NAR genomics and bioinformatics (01-06-2023)“…Abstract High throughput sequencing of adaptive immune receptor repertoire (AIRR-seq) has provided numerous human immunoglobulin (IG) sequences allowing…”
Get full text
Journal Article -
5
Evidence of somatic hypermutation in the antigen binding sites of patients with CLL harboring IGHV genes with 100% germline identity
Published in Frontiers in oncology (2022)“…Classification of patients with chronic lymphocytic leukemia (CLL) based on the somatic hypermutation (SHM) status of the clonotypic immunoglobulin heavy…”
Get full text
Journal Article -
6
Immunoglobulin Gene Mutational Status Assessment by Next Generation Sequencing in Chronic Lymphocytic Leukemia
Published in Methods in molecular biology (Clifton, N.J.) (2022)“…B cell receptor (BcR) immunoglobulins (IG) display a tremendous diversity due to complex DNA rearrangements, the V(D)J recombination, further enhanced by the…”
Get more information
Journal Article -
7
The immunopathological landscape of human pre-TCRα deficiency: From rare to common variants
Published in Science (American Association for the Advancement of Science) (01-03-2024)“…We describe humans with rare biallelic loss-of-function variants impairing pre-α T cell receptor (pre-TCRα) expression. Low circulating naive αβ T cell counts…”
Get full text
Journal Article -
8
Epstein-Barr Virus and immune status imprint the immunogenomics of non-Hodgkin lymphomas occurring in immune-suppressed environments
Published in Haematologica (Roma) (06-06-2024)“…Non-Hodgkin lymphomas (NHL) commonly occur in immune-deficient (ID) patients, both HIV-infected and transplanted, and are often EBV-driven with cerebral…”
Get full text
Journal Article -
9
Erratum To: The helicases DinG, Rep and UvrD cooperate to promote replication across transcription units in vivo
Published in The EMBO journal (06-01-2010)Get full text
Journal Article -
10
The helicases DinG, Rep and UvrD cooperate to promote replication across transcription units in vivo
Published in The EMBO journal (06-01-2010)Get full text
Journal Article