Search Results - "de Ru, AH"
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T cells targeted to TdT kill leukemic lymphoblasts while sparing normal lymphocytes
Published in Nature biotechnology (01-04-2022)“…Unlike chimeric antigen receptors, T-cell receptors (TCRs) can recognize intracellular targets presented on human leukocyte antigen (HLA) molecules. Here we…”
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Human islets and dendritic cells generate post‐translationally modified islet autoantigens
Published in Clinical and experimental immunology (01-08-2016)“…Summary The initiation of type 1 diabetes (T1D) requires a break in peripheral tolerance. New insights into neoepitope formation indicate that…”
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Morphological changes during dendritic cell maturation correlate with cofilin activation and translocation to the cell membrane
Published in European journal of immunology (01-01-2004)“…Upon activation, tissue residing immature dendritic cells (DC) start to migrate towards the draining lymph node and mature into efficient antigen‐presenting…”
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Efficiency and Mechanism of Antigen-specific CD8+ T-cell Activation Using Synthetic Long Peptides
Published in Journal of immunotherapy (1997) (01-02-2012)“…Synthetic long peptides that contain immunogenic T-cell epitopes have been used to induce activation of antigen-specific CD8 T cells in vitro for immune…”
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A Structural Model of Pestivirus E rns Based on Disulfide Bond Connectivity and Homology Modeling Reveals an Extremely Rare Vicinal Disulfide
Published in Journal of virology (15-10-2002)“…ABSTRACT E rns is a pestivirus envelope glycoprotein and is the only known viral surface protein with RNase activity. E rns is a disulfide-linked homodimer of…”
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Proteosomal degradation of BCR/ABL protein can generate an HLA-A0301-restricted peptide, but high-avidity T cells recognizing this leukemia-specific antigen were not demonstrated
Published in Haematologica (Roma) (01-09-2004)“…Dept. of Hematology, Leiden, University Medical Center, PO Box 9600, 2300 RC, The Netherlands. posthuma@rdgg.nl BACKGROUND AND OBJECTIVES: Cytotoxic…”
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A Structural Model of Pestivirus E super(rns) Based on Disulfide Bond Connectivity and Homology Modeling Reveals an Extremely Rare Vicinal Disulfide
Published in Journal of virology (01-10-2002)“…E super(rns) is a pestivirus envelope glycoprotein and is the only known viral surface protein with RNase activity. E super(rns) is a disulfide-linked…”
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