Search Results - "de Rooij, Felix W. M"

Bacterial infections in cirrhosis: role of proton pump inhibitors and intestinal permeability by van Vlerken, Lotte G., Huisman, Ellen J., van Hoek, Bart, Renooij, Willem, de Rooij, Felix W. M., Siersema, Peter D., van Erpecum, Karel J.

“…Eur J Clin Invest 2012; 42 (7): 760–767 Background  Cirrhotic patients are at considerable risk for bacterial infections, possibly through increased intestinal…”
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The Relationship of Metabolic Syndrome Traits with Beta-Cell Function and Insulin Sensitivity by Oral Minimal Model Assessment in South Asian and European Families Residing in the Netherlands by Sijbrands, Eric J. G., Kokkinos, Alexander, de Rooij, Felix W. M., Özcan, Behiye, Jainandunsing, Sjaam, Geragotou, Thekla, Tentolouris, Nicholas

“…Background. There are different metabolic syndrome traits among patients with different ethnicities. Methods. We investigated this by studying 44 South Asians…”
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High cancer risk and increased mortality in patients with Peutz-Jeghers syndrome by van Lier, Margot G F, Westerman, Anne Marie, Wagner, Anja, Looman, Caspar W N, Wilson, J H Paul, de Rooij, Felix W M, Lemmens, Valery E P P, Kuipers, Ernst J, Mathus-Vliegen, Elisabeth M H, van Leerdam, Monique E

“…Peutz-Jeghers syndrome (PJS) is associated with an increased cancer risk. As the determination of optimal surveillance strategies is hampered by wide ranges in…”
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Failing beta-cell adaptation in South Asian families with a high risk of type 2 diabetes by Jainandunsing, Sjaam, Özcan, Behiye, Rietveld, Trinet, van Miert, Joram N. I., Isaacs, Aaron J., Langendonk, Janneke G., de Rooij, Felix W. M., Sijbrands, Eric J. G.

“…We performed an extended oral glucose tolerance test (OGTT) to investigate the relationship between early and late beta-cell response and type 2 diabetes (T2D)…”
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A stable isotope method for in vivo assessment of human insulin synthesis and secretion by Jainandunsing, Sjaam, van Miert, Joram N. I., Rietveld, Trinet, Darcos Wattimena, J. L., Sijbrands, Eric J. G., de Rooij, Felix W. M.

“…Aims In vitro, beta cells immediately secrete stored but readily releasable insulin in response to a rise of glucose. During a prolonged insulin response, this…”
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Afamelanotide for Erythropoietic Protoporphyria by Langendonk, Janneke G, Balwani, Manisha, Anderson, Karl E, Bonkovsky, Herbert L, Anstey, Alexander V, Bissell, D. Montgomery, Bloomer, Joseph, Edwards, Chris, Neumann, Norbert J, Parker, Charles, Phillips, John D, Lim, Henry W, Hamzavi, Iltefat, Deybach, Jean-Charles, Kauppinen, Raili, Rhodes, Lesley E, Frank, Jorge, Murphy, Gillian M, Karstens, Francois P.J, Sijbrands, Eric J.G, de Rooij, Felix W.M, Lebwohl, Mark, Naik, Hetanshi, Goding, Colin R, Wilson, J.H. Paul, Desnick, Robert J

“…In patients with erythropoietic protoporphyria, sensitivity to the sun leads to pain and compromised quality of life. In two clinical trials, one in Europe and…”
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Novel null-allele mutations and genotype-phenotype correlation in Argentinean patients with erythropoietic protoporphyria by Parera, Victoria E, Koole, Rita H, Minderman, Gardi, Edixhoven, Annie, Rossetti, Maria V, Batlle, Alcira, de Rooij, Felix W M

“…Erythropoietic protoporphyria (EPP) is an inherited disorder of porphyrin metabolism in which decreased activity of ferrochelatase (FECH) leads to accumulation…”
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CARD15 mutations in Dutch familial and sporadic inflammatory bowel disease and an overview of European studies by van der Linde, Klaas, Boor, Patrick P.C, Houwing-Duistermaat, Jeanine J, Crusius, Bart J.A, Wilson, Paul J.H, Kuipers, Ernst J, de Rooij, Felix W.M

“…OBJECTIVESThe single nucleotide variations R702W, G908R and L1007fs in the CARD15 gene have been found to be independently associated with Crohnʼs disease. The…”
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Cyclooxygenase 2 Expression and Molecular Alterations in Peutz-Jeghers Hamartomas and Carcinomas by DE LENG, Wendy W. J, WESTERMAN, Anne Marie, KELLER, Josbert J, WETERMAN, Marian A. J, DE ROOIJ, Felix W. M, VAN DEKKEN, Herman, DE GOEIJ, Anton F. P. M, GRUBER, Stephen B, WILSON, J. H, OFFERHAUS, G. Johan A, GIARDIELLO, Francis M

“…Purpose: Peutz-Jeghers syndrome (PJS) is a hamartomatous polyposis disorder with a high cancer risk. Debate exists about the premalignant potential of…”
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Nasal polyposis in Peutz–Jeghers syndrome: a distinct histopathological and molecular genetic entity by de Leng, Wendy W J, Westerman, Anne Marie, Weterman, Marian A J, Jansen, Marnix, van Dekken, Herman, Giardiello, Francis M, de Rooij, Felix W M, Paul Wilson, J H, Offerhaus, G Johan A, Keller, Josbert J

“…Background: Peutz–Jeghers syndrome (PJS) is an autosomal dominant hamartomatous polyposis syndrome of the gastrointestinal tract, caused by a germline…”
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Age-related obesity and type 2 diabetes dysregulate neuronal associated genes and proteins in humans by Rahimi, Mehran, Vinciguerra, Manlio, Daghighi, Mojtaba, Özcan, Behiye, Akbarkhanzadeh, Vishtaseb, Sheedfar, Fareeba, Amini, Marzyeh, Mazza, Tommaso, Pazienza, Valerio, Motazacker, Mahdi M, Mahmoudi, Morteza, De Rooij, Felix W M, Sijbrands, Eric, Peppelenbosch, Maikel P, Rezaee, Farhad

“…Despite numerous developed drugs based on glucose metabolism interventions for treatment of age-related diseases such as diabetes neuropathies (DNs), DNs are…”
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Transcription factor 7-like 2 gene links increased in vivo insulin synthesis to type 2 diabetes by Jainandunsing, Sjaam, Koole, H. Rita, van Miert, Joram N.I., Rietveld, Trinet, Wattimena, J.L. Darcos, Sijbrands, Eric J.G., de Rooij, Felix W.M.

“…Transcription factor 7-like 2 (TCF7L2) is the main susceptibility gene for type 2 diabetes, primarily through impairing the insulin secretion by pancreatic β…”
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Post-glucose-load urinary C-peptide and glucose concentration obtained during OGTT do not affect oral minimal model-based plasma indices by Jainandunsing, Sjaam, Wattimena, J. L. Darcos, Rietveld, Trinet, van Miert, Joram N. I., Sijbrands, Eric J. G., de Rooij, Felix W. M.

“…The purpose of this study was to investigate how renal loss of both C-peptide and glucose during oral glucose tolerance test (OGTT) relate to and affect…”
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Discriminative Ability of Plasma Branched-Chain Amino Acid Levels for Glucose Intolerance in Families At Risk for Type 2 Diabetes by Jainandunsing, Sjaam, Wattimena, J L Darcos, Verhoeven, Adrie J M, Langendonk, Janneke G, Rietveld, Trinet, Isaacs, Aaron J, Sijbrands, Eric J G, de Rooij, Felix W M

“…Insulin resistance and glucose intolerance have been associated with increased plasma levels of branched-chain amino acids (BCAA). BCAA levels do not predict…”
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Bile acids and Barrett's oesophagus: A sine qua non or coincidence? by Sital, Rudy R., Kusters, Johannes G., De Rooij, Felix W. M., Kuipers, Ernst J., Siersema, Peter D.

“…Background. Barrett's oesophagus (BO), a premalignant condition associated with the development of oesophageal adenocarcinoma (OAC), is thought to be a…”
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CARD15 and Crohn's disease: Healthy homozygous carriers of the 3020insC frameshift mutation by VAN DER LINDE, Klaas, BOOR, Patrick P. C, HOUWING-DUISTERMAAT, Jeanine J, KUIPERS, Ernst J, WILSON, J. H, DE ROOIJ, Felix W. M

“…Single nucleotide variations in the CARD15 gene have recently been shown to be associated with Crohn's disease (CD). Of special interest is a cytosine…”
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Frequency and Spectrum of Cancers in the Peutz-Jeghers Syndrome by HEARLE, Nicholas, SCHUMACHER, Valerie, TRIMBATH, Jill D, GIARDIELLO, Francis M, GRUBER, Stephen B, OFFERHAUS, G. Johan A, DE ROOIJ, Felix W. M, WILSON, J. H. Paul, HANSMANN, Anika, MÖSLEIN, Gabriela, ROYER-POKORA, Brigitte, TILMANVOGEL, MENKO, Fred H, PHILLIPS, Robin K. S, SPIGELMAN, Allan D, HOULSTON, Richard S, OLSCHWANG, Sylviane, BOARDMAN, Lisa A, GILLE, Johan J. P, KELLER, Josbert J, WESTERMAN, Anne Marie, SCOTT, Rodney J, LIM, Wendy

“…Background: Although an increased cancer risk in Peutz-Jeghers syndrome is established, data on the spectrum of tumors associated with the disease and the…”
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Relative frequency and morphology of cancers in STK11 mutation carriers by Lim, Wendy, Olschwang, Sylviane, Keller, Josbert J., Westerman, Anne Marie, Menko, Fred H., Boardman, Lisa A., Scott, Rodney J., Trimbath, Jill, Giardiello, Francis M., Gruber, Stephen B., Gille, Johan J.P., Offerhaus, G.Johan A., de Rooij, Felix W.M., Wilson, J.H.Paul, Spigelman, Allan D., Phillips, Robin K.S., Houlston, Richard S.

“…Background & Aims: There is limited data on the spectrum and risk for cancer associated with germline serine/threonine protein kinase 11 ( STK11) mutations…”
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Card15and Crohn's Disease: Healthy Homozygous Carriers of The 3020Insc Frameshift Mutation by van der Linde, Klaas, Boor, Patrick P C, Houwing-Duistermaat, Jeanine J, Kuipers, Ernst J, Wilson, Paul J H, de Rooij, Felix W M

“…Single nucleotide variations in the CARD15 gene have recently been shown to be associated with Crohn's disease (CD). Of special interest is a cytosine…”
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Peutz-Jeghers syndrome: 78-year follow-up of the original family by Westerman, Anne Marie, Entius, Mark M, de Baar, Ellen, Boor, Patrick PC, Koole, Rita, van Velthuysen, M Loes F, Offerhaus, G Johan A, Lindhout, Dick, de Rooij, Felix WM, Wilson, JH Paul

“…The association between heredity, gastrointestinal polyposis, and mucocutaneous pigmentation in Peutz-Jeghers syndrome (PJS) was first recognised in 1921 by…”
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