Search Results - "de Roo, Guy"

Influence of growth stage on activities of polyhydroxyalkanoate (PHA) polymerase and PHA depolymerase in Pseudomonas putida U by Ren, Qun, de Roo, Guy, Witholt, Bernard, Zinn, Manfred, Thöny-Meyer, Linda

“…Medium chain length (mcl-) polyhydroxyalkanoates (PHA) are synthesized by many bacteria in the cytoplasm as storage compounds for energy and carbon. The key…”
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Preclinical profile of the HER2-targeting ADC SYD983/SYD985: introduction of a new duocarmycin-based linker-drug platform by Dokter, Wim, Ubink, Ruud, van der Lee, Miranda, van der Vleuten, Monique, van Achterberg, Tanja, Jacobs, Danielle, Loosveld, Eline, van den Dobbelsteen, Diels, Egging, David, Mattaar, Ellen, Groothuis, Patrick, Beusker, Patrick, Coumans, Ruud, Elgersma, Ronald, Menge, Wiro, Joosten, John, Spijker, Henri, Huijbregts, Tijl, de Groot, Vincent, Eppink, Michel, de Roo, Guy, Verheijden, Gijs, Timmers, Marco

“…A linker-drug platform was built on the basis of a cleavable linker-duocarmycin payload for the development of new-generation antibody-drug conjugates (ADC). A…”
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Identification of Two Acyl-CoA Synthetases from Pseudomonas putida GPo1: One is Located at the Surface of Polyhydroxyalkanoates Granules by Ruth, Katinka, Roo, Guy de, Egli, Thomas, Ren, Qun

“…Pseudomonas putida GPo1 is able to accumulate polyhydroxyalkanoates (PHA) in the form of intracellular granules as storage materials. PHA granules were…”
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A comparison of anti-HER2 IgA and IgG1 in vivo efficacy is facilitated by high N-glycan sialylation of the IgA by Rouwendal, Gerard Ja, van der Lee, Miranda M, Meyer, Saskia, Reiding, Karli R, Schouten, Jan, de Roo, Guy, Egging, David F, Leusen, Jeanette Hw, Boross, Peter, Wuhrer, Manfred, Verheijden, Gijs F, Dokter, Wim H, Timmers, Marco, Ubink, Ruud

“…Monomeric IgA has been proposed as an alternative antibody format for cancer therapy. Here, we present our studies on the production, purification and…”
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Exploitation of the S-layer self-assembly system for site directed immobilization of enzymes demonstrated for an extremophilic laminarinase from Pyrococcus furiosus by Tschiggerl, Helga, Breitwieser, Andreas, de Roo, Guy, Verwoerd, Theo, Schäffer, Christina, Sleytr, Uwe B.

“…A fusion protein based on the S-layer protein SbpA from Bacillus sphaericus CCM 2177 and the enzyme laminarinase (LamA) from Pyrococcus furiosus was designed…”
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Accumulation of Polyhydroxyalkanoate from Styrene and Phenylacetic Acid by Pseudomonas putida CA-3 by Ward, Patrick G, de Roo, Guy, O'Connor, Kevin E

“…Pseudomonas putida CA-3 is capable of converting the aromatic hydrocarbon styrene, its metabolite phenylacetic acid, and glucose into polyhydroxyalkanoate…”
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Production of chiral R-3-hydroxyalkanoic acids and R-3-hydroxyalkanoic acid methylesters via hydrolytic degradation of polyhydroxyalkanoate synthesized by pseudomonads by de Roo, Guy, Kellerhals, Michele B., Ren, Qun, Witholt, Bernard, Kessler, Birgit

“…A novel and efficient method for the production of enantiomericaly pure R‐3‐hydroxyalkanoic acids and R‐3‐hydroxyalkanoic acid methylesters was developed. The…”
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Overexpression and characterization of medium-chain-length polyhydroxyalkanoate granule bound polymerases from Pseudomonas putida GPo1 by Ren, Qun, de Roo, Guy, Witholt, Bernard, Zinn, Manfred, Thöny-Meyer, Linda

“…Polyhydroxyalkanoates (PHA) are synthesized by many bacteria in the cytoplasm as storage compounds for energy and carbon. The key enzymes for PHA biosynthesis…”
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Development of an improved in vitro activity assay for medium chain length PHA polymerases based on CoenzymeA release measurements by de Roo, Guy, Ren, Qun, Witholt, Bernard, Kessler, Birgit

“…An improved activity assay for polyhydroxyalkanoate (PHA) polymerases from Pseudomonas oleovorans GPo1 was developed. The activity assay is based on the…”
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Evidence of medium-chain-length polyhydroxyoctanoate accumulation in transgenic potato lines expressing the Pseudomonas oleovorans Pha-C1 polymerase in the cytoplasm by Romano, Andrea, Vreugdenhil, Dick, Jamar, Diaan, van der Plas, Linus H.W., de Roo, Guy, Witholt, Bernard, Eggink, Gerrit, Mooibroek, Hans

“…The phaC1 gene from Pseudomonas oleovorans, coding for the Pha-C1 polymerase, was introduced into the potato genome. Transgenic callus and plant lines which…”
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Simultaneous Accumulation and Degradation of Polyhydroxyalkanoates: Futile Cycle or Clever Regulation? by Ren, Qun, de Roo, Guy, Ruth, Katinka, Witholt, Bernard, Zinn, Manfred, Thöny-Meyer, Linda

“…The regulation of medium-chain-length polyhydroxyalkanoates (mcl-PHA) metabolism in Pseudomonas putida GPo1 was studied by analysis of enzymes bound to PHA…”
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Engineering of Biological Systems for the Synthesis of Tailor-made Polyhydroxyalkanoates, a Class of Versatile Polymers by Birgit Kessler, Qun Ren, Guy de Roo, Maria A. Prieto, Bernard Witholt

“…Medium-chain-length polyhydroxyalkanoates (mcl-PHAs) are bacterial polyesters which are produced in nature by certain Pseudomonas strains. These biopolymers…”
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O-035 Efficacy of Anti-inflammatory Monoclonal Secretory Immunoglobulin-A Antibodies after Oral Treatment in Preclinical Models of Inflammatory Bowel Disease by Arends, Roel, Weigmann, Benno, Ubink, Ruud, van der Lee, Miranda, de Roo, Guy, Corthesy, Blaise, Dokter, Wim, Neurath, Markus

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Abstract 2651: Impressive efficacy and safety profile of a novel generation duocarmycin-based HER2-targeting ADC by Dokter, Willem, Ubink, Ruud, Lee, Miranda van der, Vleuten, Monique van der, Achterberg, Tanja van, Jacobs, Daniëlle, Dobbelsteen, Diels van den, Egging, David, Mattaar, Ellen, Groothuis, Patrick, Beusker, Patrick, Coumans, Ruud, Elgersma, Ronald, Eppink, Michel, Roo, Guy de, Verheijden, Gijs, Timmers, Marco

“…Abstract We have built a linker-drug platform based on a cleavable linker-duocarmycin payload for the development of novel generation antibody-drug conjugates…”
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Self-packed filter plates: A good alternative for pre-packed filter plates for developing purification processes for therapeutic proteins by Li, Xiaonan, de Roo, Guy, Burgers, Kim, Ottens, Marcel, Eppink, Michel

“…The use of high‐throughput screening (HTS) has been successfully applied over the past years in downstream process development of therapeutic proteins…”
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Influence of growth stage on activities of polyhydroxyalkanoate by Ren, Qun, de Roo, Guy, Witholt, Bernard, Zinn, Manfred, Thöny-Meyer, Linda

“…Medium chain length (mcl-) polyhydroxyalkanoates (PHA) are synthesized by many bacteria in the cytoplasm as storage compounds for energy and carbon. The key…”
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Poly(3-hydroxyalkanoate) polymerase synthesis and in vitro activity in recombinant Escherichia coli and Pseudomonas putida by QUN REN, DE ROO, Guy, VAN BEILEN, Jan B, ZINN, Manfred, KESSLER, Birgit, WITHOLT, Bernard

“…We tested the synthesis and in vitro activity of the poly(3-hydroxyalkanoate) (PHA) polymerase 1 from Pseudomonas putida GPo1 in both P. putida GPp104 and…”
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Purification and characterization of cystathionine γ-lyase from lactococcus lactis subsp. cremoris SK11 : Possible role in flavor compound formation during cheese maturation by BRUINENBERG, P. G, DE ROO, G, LIMSOWTIN, G. K. Y

“…A cystathionine gamma-lyase was purified to homogeneity from a crude cell extract of Lactococcus lactis subsp. cremoris SK11 by a procedure including…”
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Recovery of active medium-chain-length-poly-3-hydroxyalkanoate polymerase from inactive inclusion bodies using ion-exchange resin by Ren, Q, De Roo G, Kessler, B, Witholt, B

“…A novel process for the purification of active medium-chain-length-polyhydroxyalkanoate (mcl-PHA) polymerase was developed. This process is based on…”
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Role of phaD in Accumulation of Medium-Chain-Length Poly(3-Hydroxyalkanoates) inPseudomonas oleovorans by Stefan Klinke, Guy de Roo, Bernard Witholt, Birgit Kessler

“…Classifications Services AEM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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