Search Results - "de Rienzo, Gianluca"

Extracellular Vesicles Modulate the Glioblastoma Microenvironment via a Tumor Suppression Signaling Network Directed by miR-1 by BRONISZ, Agnieszka, YAN WANG, OSTROWSKI, Michael C, HOCHBERG, Fred, WEISSLEDER, Ralph, LAWLER, Sean E, CHIOCCA, E. Antonio, GODLEWSKI, Jakub, NOWICKI, Michal O, PERUZZI, Pierpaolo, ANSARI, Khairul I, OGAWA, Daisuke, BALAJ, Leonora, DE RIENZO, Gianluca, MINEO, Marco, NAKANO, Ichiro

“…Extracellular vesicles have emerged as important mediators of intercellular communication in cancer, including by conveying tumor-promoting microRNAs between…”
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Brain activity patterns in high-throughput electrophysiology screen predict both drug efficacies and side effects by Eimon, Peter M., Ghannad-Rezaie, Mostafa, De Rienzo, Gianluca, Allalou, Amin, Wu, Yuelong, Gao, Mu, Roy, Ambrish, Skolnick, Jeffrey, Yanik, Mehmet Fatih

“…Neurological drugs are often associated with serious side effects, yet drug screens typically focus only on efficacy. We demonstrate a novel paradigm utilizing…”
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Zebrafish homologs of genes within 16p11.2, a genomic region associated with brain disorders, are active during brain development, and include two deletion dosage sensor genes by Blaker-Lee, Alicia, Gupta, Sunny, McCammon, Jasmine M, De Rienzo, Gianluca, Sive, Hazel

“…Deletion or duplication of one copy of the human 16p11.2 interval is tightly associated with impaired brain function, including autism spectrum disorders…”
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Efficient shRNA-mediated inhibition of gene expression in zebrafish by De Rienzo, Gianluca, Gutzman, Jennifer H, Sive, Hazel

“…Despite the broad repertoire of loss of function (LOF) tools available for use in the zebrafish, there remains a need for a simple and rapid method that can…”
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Common DISC1 Polymorphisms Disrupt Wnt/GSK3β Signaling and Brain Development by Singh, Karun K., De Rienzo, Gianluca, Drane, Laurel, Mao, Yingwei, Flood, Zachary, Madison, Jon, Ferreira, Manuel, Bergen, Sarah, King, Cillian, Sklar, Pamela, Sive, Hazel, Tsai, Li-Huei

“…Disrupted in Schizophrenia-1 (DISC1) is a candidate gene for psychiatric disorders and has many roles during brain development. Common DISC1 polymorphisms…”
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Volumetric absorptive microsampling as an effective microsampling technique for LC–MS/MS bioanalysis of biomarkers in drug discovery by Kapadnis, Unnati, Locuson, Chuck, Okamura, Heidi, Rienzo, Gianluca De, Cotter, Cece, Zhu, Dongwei, Narayanaswami, Rohini, Castro-Perez, Jose, Marathe, Punit, Yang, Wen-Chu

“…Develop and validate a volumetric absorptive microsampling (VAMS)-based LC–MS/MS method to support the bioanalysis of amino acid and carboxylic acid biomarkers…”
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Disc1 regulates both β‐catenin‐mediated and noncanonical Wnt signaling during vertebrate embryogenesis by De Rienzo, Gianluca, Bishop, Joshua A., Mao, Yingwei, Pan, Luyuan, Ma, Taylur P., Moens, Cecilia B., Tsai, Li‐Huei, Sive, Hazel

“…ABSTRACT Disc1 is a schizophrenia risk gene that engages multiple signaling pathways during neurogenesis and brain development. Using the zebrafish as a tool,…”
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Characterization and Classification of Zebrafish Brain Morphology Mutants by Lowery, Laura Anne, De Rienzo, Gianluca, Gutzman, Jennifer H., Sive, Hazel

“…The mechanisms by which the vertebrate brain achieves its three‐dimensional structure are clearly complex, requiring the functions of many genes. Using the…”
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Common DISC1 Polymorphisms Disrupt Wnt/GSK3[beta] Signaling and Brain Development by Singh, Karun K, De Rienzo, Gianluca, Drane, Laurel, Mao, Yingwei, Flood, Zachary, Madison, Jon, Ferreira, Manuel, Bergen, Sarah, King, Cillian, Sklar, Pamela, Sive, Hazel, Tsai, Li-Huei

“…Disrupted in Schizophrenia-1 (DISC1) is a candidate gene for psychiatric disorders and has many roles during brain development. Common DISC1 polymorphisms…”
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Common DISC1 Polymorphisms Disrupt Wnt/GSK3I super(2) Signaling and Brain Development by Singh, Karun K, De Rienzo, Gianluca, Drane, Laurel, Mao, Yingwei, Flood, Zachary, Madison, Jon, Ferreira, Manuel, Bergen, Sarah, King, Cillian, Sklar, Pamela, Sive, Hazel, Tsai, Li-Huei

“…Disrupted in Schizophrenia-1 (DISC1) is a candidate gene for psychiatric disorders and has many roles during brain development. Common DISC1 polymorphisms…”
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The expression level of frog relaxin mRNA (fRLX), in the testis of Rana esculenta, is influenced by testosterone by De Rienzo, Gianluca, Aniello, Francesco, Branno, Margherita, Izzo, Gaia, Minucci, Sergio

“…Frog relaxin (fRLX) belongs to the relaxin/insulin gene family present in the testis of Rana esculenta and is specifically expressed by Leydig cells. Since the…”
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Isolation and Characterization of a Novel Member of the Relaxin/Insulin Family from the Testis of the Frog Rana esculenta by de Rienzo, Gianluca, Aniello, Francesco, Branno, Margherita, Minucci, Sergio

“…Abstract A complementary DNA (cDNA) encoding a frog relaxin/insulin member family (fRLX) from testis cDNA library was isolated and characterized. The fRLX cDNA…”
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Ethane 1,2-dimethane sulphonate is a useful tool for studying cell-to-cell interactions in the testis of the frog, Rana esculenta by Palmiero, Carmela, Ferrara, Diana, De Rienzo, Gianluca, d’Istria, Michela, Minucci, Sergio

“…Ethane 1,2-dimethane sulphonate (EDS), a toxin which specifically destroys Leydig cells (LC), has been used to study cellular interactions in the testis of the…”
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Isolation and Characterization of a Novel Member of the Relaxin/Insulin Family from the Testis of the Frog Rana esculenta1 by de Rienzo, Gianluca, Aniello, Francesco, Branno, Margherita, Minucci, Sergio

“…A complementary DNA (cDNA) encoding a frog relaxin/insulin member family (fRLX) from testis cDNA library was isolated and characterized. The fRLX cDNA…”
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Effects of melatonin treatment on Leydig cell activity in the testis of the frog Rana esculenta by d'Istria, Michela, Serino, Ismene, Izzo, Gaia, Ferrara, Diana, De Rienzo, Gianluca, Minucci, Sergio

“…This study was conducted to verify the effect(s) of melatonin treatment on frog Leydig cells. Morphological observation after melatonin treatment indicates…”
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Morphology of the Harderian gland of the Gecko, Tarentola mauritanica by Chieffi Baccari, Gabriella, Chieffi, Giovanni, Di Matteo, Loredana, Dafnis, Demetrio, De Rienzo, Gianluca, Minucci, Sergio

“…ABSTRACT The Harderian gland of the gecko, Tarentola mauritanica, was studied at the histological, histochemical, and ultrastructural levels. It is a nonlobate…”
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First evidence of prothymosin α in a non-mammalian vertebrate and its involvement in the spermatogenesis of the frog Rana esculenta by Aniello, Francesco, Branno, Margherita, De Rienzo, Gianluca, Ferrara, Diana, Palmiero, Carmela, Minucci, Sergio

“…A cDNA clone encoding for a Prothymosin α (Prot-α) has been isolated and characterized from the testis of the frog Rana esculenta. Frog Prothymosin α (fProt-α)…”
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Temporal and spatial localization of prothymosin α transcript in the Harderian gland of the frog, Rana esculenta by de Rienzo, Gianluca, di Sena, Rona, Ferrara, Diana, Palmiero, Carmela, Baccari, Gabriella Chieffi, Minucci, Sergio

“…The Harderian gland (hg) is the only orbital gland of the frog Rana esculenta, and it has the essential function of lubricating the eyes. The hg secretory…”
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Effects of multiple injections of ethane 1,2-dimethane sulphonate (EDS) on the frog, Rana esculenta, testicular activity by Minucci, Sergio, de Rienzo, Gianluca, di Sena, Rona, Cobellis, Gilda, Meccariello, Rosaria, Pierantoni, Riccardo, Fasano, Silvia

“…Ethane 1,2‐dimethane sulphonate (EDS) is an alkylating agent, which has a selective cytotoxic effect on Leydig cells in some mammalian species. Similarly, in…”
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