Search Results - "de Ridder, M A"
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1
Activation of c-MET induces a stem-like phenotype in human prostate cancer
Published in PloS one (14-11-2011)“…Prostate cancer consists of secretory cells and a population of immature cells. The function of immature cells and their mutual relation with secretory cells…”
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2
Viability Analysis and High-Content Live-Cell Imaging for Drug Testing in Prostate Cancer Xenograft-Derived Organoids
Published in Cells (Basel, Switzerland) (12-05-2023)“…Tumor organoids have been pushed forward as advanced model systems for in vitro oncology drug testing, with the eventual goal to direct personalized cancer…”
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3
The effect of emergency department pharmacists on drug overuse and drug underuse in patients with an ADE-related hospitalisation: a controlled intervention study
Published in BMC health services research (17-11-2022)“…Abstract Background Drug overuse or drug underuse are the most common causes of adverse drug events and can lead to hospital admissions. Using clinical…”
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4
Fertility and Ovarian Function in High-Dose Estrogen-Treated Tall Women
Published in The journal of clinical endocrinology and metabolism (01-04-2011)“…High-dose estrogen-treated tall women are at risk of subfertility in later life; treated women exhibit signs of accelerated ovarian ageing with concomitant…”
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5
Combined lycopene and vitamin E treatment suppresses the growth of PC-346C human prostate cancer cells in nude mice
Published in The Journal of nutrition (01-05-2006)“…Epidemiologic studies have repeatedly associated a high intake of lycopene and vitamin E with reduced prostate cancer risk. The present study examined the…”
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6
Pre- and Intraoperative Visualization of GRPR-Expressing Solid Tumors: Preclinical Profiling of Novel Dual-Modality Probes for Nuclear and Fluorescence Imaging
Published in Cancers (05-04-2023)“…Image-guided surgery using a gastrin-releasing peptide receptor (GRPR)-targeting dual-modality probe could improve the accuracy of the resection of various…”
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7
In Vivo Efficacy Testing of Peptide Receptor Radionuclide Therapy Radiosensitization Using Olaparib
Published in Cancers (01-02-2023)“…Peptide receptor radionuclide therapy (PRRT), a form of internal targeted radiation treatment using [ Lu]Lu [DOTA -Tyr ]octreotate, is used to treat patients…”
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The Effect of VPA Treatment on Radiolabeled DOTATATE Uptake: Differences Observed In Vitro and In Vivo
Published in Pharmaceutics (12-01-2022)“…To improve peptide receptor radionuclide therapy (PRRT), we aimed to enhance the expression of somatostatin type-2 receptors (SSTR2) in vitro and in vivo,…”
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9
Eight Years of Growth Hormone Treatment in Children With Prader-Willi Syndrome: Maintaining the Positive Effects
Published in The journal of clinical endocrinology and metabolism (01-10-2013)“…Background: The most important reason for treating children with Prader-Willi syndrome (PWS) with GH is to optimize their body composition. Objectives: The aim…”
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10
Patient-Derived Xenografts and Organoids Recapitulate Castration-Resistant Prostate Cancer with Sustained Androgen Receptor Signaling
Published in Cells (Basel, Switzerland) (01-11-2022)“…Castration-resistant prostate cancer (CRPC) remains an incurable and lethal malignancy. The development of new CRPC treatment strategies is strongly impeded by…”
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11
Darolutamide does not interfere with OATP‐mediated uptake of docetaxel
Published in International journal of cancer (15-07-2024)“…The addition of darolutamide, an androgen receptor signalling inhibitor, to therapy with docetaxel has recently been approved as a strategy to treat metastatic…”
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12
Ex vivo treatment of prostate tumor tissue recapitulates in vivo therapy response
Published in The Prostate (01-03-2019)“…Background In vitro models of prostate cancer (PCa) are not always reliable to evaluate anticancer treatment efficacy. This limitation may be overcome by using…”
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13
Abiraterone switches castration‐resistant prostate cancer dependency from adrenal androgens towards androgen receptor variants and glucocorticoid receptor signalling
Published in The Prostate (01-04-2022)“…Introduction Castration‐resistant prostate cancer (CRPC) remains dependent on androgen receptor (AR) signalling, which is largely driven by conversion of…”
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14
Movember GAP1 PDX project: An international collection of serially transplantable prostate cancer patient‐derived xenograft (PDX) models
Published in The Prostate (01-12-2018)“…Background While it has been challenging to establish prostate cancer patient‐derived xenografts (PDXs), with a take rate of 10‐40% and long latency time,…”
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Safety of [177Lu]Lu-NeoB treatment: a preclinical study characterizing absorbed dose and acute, early, and late organ toxicity
Published in European journal of nuclear medicine and molecular imaging (01-11-2022)“…Purpose The radiolabeled gastrin-releasing peptide receptor (GRPR)-targeting antagonist NeoB is a promising radioligand for imaging and therapy of…”
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16
Androgen receptor signalling impairs docetaxel efficacy in castration-resistant prostate cancer
Published in British journal of cancer (08-12-2020)“…Androgen receptor (AR) signalling drives neoplastic growth and therapy resistance in prostate cancer. Recent clinical data show that docetaxel combined with…”
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Examining a possible association between human papilloma virus (HPV) vaccination and migraine: results of a cohort study in the Netherlands
Published in European journal of pediatrics (01-05-2015)“…Since the introduction of the bivalent human papilloma virus (HPV) vaccine in the Netherlands, migraine has been reported as a notable event in the passive…”
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18
Determinants of body composition measured by dual-energy X-ray absorptiometry in Dutch children and adolescents
Published in The American journal of clinical nutrition (01-08-1997)“…Knowledge about body composition is important in metabolic and nutritional studies. In this cross-sectional study the body composition of 403 healthy white…”
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19
Reovirus mutant jin-3 exhibits lytic and immune-stimulatory effects in preclinical human prostate cancer models
Published in Cancer gene therapy (01-06-2022)“…Treatment of castration-resistant prostate cancer remains a challenging clinical problem. Despite the promising effects of immunotherapy in other solid…”
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20
Evaluating baculovirus as a vector for human prostate cancer gene therapy
Published in PloS one (06-06-2013)“…Gene therapy represents an attractive strategy for the non-invasive treatment of prostate cancer, where current clinical interventions show limited efficacy…”
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