Search Results - "de Ridder, Gustaaf"

L-type calcium channels play a critical role in maintaining lens transparency by regulating phosphorylation of aquaporin-0 and myosin light chain and expression of connexins by Maddala, Rupalatha, Nagendran, Tharkika, de Ridder, Gustaaf G, Schey, Kevin L, Rao, Ponugoti Vasantha

“…Homeostasis of intracellular calcium is crucial for lens cytoarchitecture and transparency, however, the identity of specific channel proteins regulating…”
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BRG1 and BRM SWI/SNF ATPases redundantly maintain cardiomyocyte homeostasis by regulating cardiomyocyte mitophagy and mitochondrial dynamics in vivo by Bultman, Scott J., Holley, Darcy Wood, G. de Ridder, Gustaaf, Pizzo, Salvatore V., Sidorova, Tatiana N., Murray, Katherine T., Jensen, Brian C., Wang, Zhongjing, Bevilacqua, Ariana, Chen, Xin, Quintana, Megan T., Tannu, Manasi, Rosson, Gary B., Pandya, Kumar, Willis, Monte S.

“…There has been an increasing recognition that mitochondrial perturbations play a central role in human heart failure. Mitochondrial networks, whose function is…”
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Comparison of Acute Histologic and Biomechanical Effects of Radiofrequency Ablation and Cryoablation on Periarticular Structures in a Swine Model by Vikingstad, Eric M., MD, PhD, de Ridder, Gustaaf G., MD, PhD, Glisson, Richard R., BS, Cardona, Diana M., MD, DiPalma, Devon, Eward, William C., MD, DVM, Brigman, Brian E., MD, PhD, Nelson, Rendon C., MD, Kim, Charles Y., MD

“…Abstract Purpose To compare the acute effects of radiofrequency (RF) ablation and cryoablation on the structural integrity of nontarget periarticular tissues…”
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Binding of Tissue-type Plasminogen Activator to the Glucose-regulated Protein 78 (GRP78) Modulates Plasminogen Activation and Promotes Human Neuroblastoma Cell Proliferation in Vitro by Gonzalez-Gronow, Mario, Gomez, Cristian Farias, de Ridder, Gustaaf G., Ray, Rupa, Pizzo, Salvatore V.

“…The glucose-regulated protein 78 (GRP78) is a plasminogen (Pg) receptor on the cell surface. In this study, we demonstrate that GRP78 also binds the…”
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GRP78: a chaperone with diverse roles beyond the endoplasmic reticulum by Quinones, Quintin J, de Ridder, Gustaaf G, Pizzo, Salvatore V

“…Glucose-regulated protein 78 (GRP78) is a well-characterized molecular chaperone that is ubiquitously expressed in mammalian cells. GRP78 is best known for…”
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A murine monoclonal antibody directed against the carboxyl-terminal domain of GRP78 suppresses melanoma growth in mice by de Ridder, Gustaaf G, Ray, Rupa, Pizzo, Salvatore V

“…The HSP70 family member GRP78 is a selective tumor marker upregulated on the surface of many tumor cell types, including melanoma, where it acts as a growth…”
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Nuclear basic fibroblast growth factor regulates triple-negative breast cancer chemo-resistance by Li, Shenduo, Payne, Sturgis, Wang, Fang, Claus, Peter, Su, Zuowei, Groth, Jeffrey, Geradts, Joseph, de Ridder, Gustaaf, Alvarez, Rebeca, Marcom, Paul Kelly, Pizzo, Salvatore V, Bachelder, Robin E

“…Chemotherapy remains the only available treatment for triple-negative (TN) breast cancer, and most patients exhibit an incomplete pathologic response. Half of…”
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Malignant mesothelioma not related to asbestos exposure: Analytical scanning electron microscopic analysis of 83 cases and comparison with 442 asbestos-related cases by Kraynie, Alyssa, de Ridder, Gustaaf G., Sporn, Thomas A., Pavlisko, Elizabeth N., Roggli, Victor L.

“…Epidemiological studies indicate that 80-90% of mesotheliomas are asbestos related. This suggests that 10-20% are not. Lung fiber burden analysis provides…”
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The Escherichia coli Subtilase Cytotoxin A Subunit Specifically Cleaves Cell-surface GRP78 Protein and Abolishes COOH-terminal-dependent Signaling by Ray, Rupa, de Ridder, Gustaaf G., Eu, Jerry P., Paton, Adrienne W., Paton, James C., Pizzo, Salvatore V.

“…GRP78, a molecular chaperone with critical endoplasmic reticulum functions, is aberrantly expressed on the surface of cancer cells, including prostate and…”
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Asbestos content of lung tissue in patients with malignant peritoneal mesothelioma: A study of 42 cases by de Ridder, Gustaaf G., Kraynie, Alyssa, Pavlisko, Elizabeth N., Oury, Tim D., Roggli, Victor L.

“…Lung tissue from 42 peritoneal mesothelioma cases was analyzed by light microscopy and scanning electron microscopy/energy dispersive spectrometry. There were…”
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Spinal Anesthetic in a Patient With a Platelet Count of 7000 × 109/L and Undiagnosed Thrombotic Thrombocytopenic Purpura: A Case Report by Straube, Lacey E., de Ridder, Gustaaf G., Huber, Christopher A., Blacker, Samuel N.

“…A parturient with unknown thrombotic thrombocytopenic purpura (TTP) received spinal anesthesia for cesarean delivery with subsequent discovery of a platelet…”
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Autoantibodies against cell surface GRP78 promote tumor growth in a murine model of melanoma by de Ridder, Gustaaf G, Gonzalez-Gronow, Mario, Ray, Rupa, Pizzo, Salvatore V

“…Autoantibodies that react with GRP78 expressed on the cell-surface of many tumor cell lines occur in the sera of patients with prostate cancer, melanoma, and…”
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Changes in oligosaccharide chains of autoantibodies to GRP78 expressed during progression of malignant melanoma stimulate melanoma cell growth and survival by Selim, Maria A, Burchette, James L, Bowers, Edith V, de Ridder, Gustaaf G, Mo, Lihong, Pizzo, Salvatore V, Gonzalez-Gronow, Mario

“…A correlation between expression of the glucose-regulated protein of 78 kDa (GRP78) in malignant melanoma tumors and poor patient survival is well established…”
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Abstract 4146037: Navigating the Diagnostic Challenges and Therapeutic Landscape of Giant Cell Myocarditis: A Compelling Case Study of Survival and Recovery by Bitton, Neria, Caplan, Alex, Nelson, Favour, Olenginski, Gregory, Gonter, Aric, de Ridder, Gustaaf, Carry, Brendan, henry, Lucie

“…Abstract only Introduction: Giant cell myocarditis (GCM), a rare and often fatal heart disease, presents diagnostic challenges due to its varied symptoms…”
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Novel venous thromboembolism mouse model to evaluate the role of complete and partial factor XIII deficiency in pulmonary embolism risk by Kattula, Sravya, Sang, Yaqiu, Ridder, Gustaaf, Silver, Anna C., Bouck, Emma G., Cooley, Brian C., Wolberg, Alisa S.

“…Background Venous thrombosis (VT) and pulmonary embolism (PE), collectively venous thromboembolism (VTE), cause high mortality and morbidity. Factor XIII…”
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Race, rituximab, and relapse in TTP by Chaturvedi, Shruti, Antun, Ana G, Farland, Andrew M, Woods, Ryan, Metjian, Ara, Park, Yara A, de Ridder, Gustaaf, Gibson, Briana, Kasthuri, Raj S, Liles, Darla K, Akwaa, Frank, Clover, Todd, Baumann Kreuziger, Lisa, Sadler, J Evan, Sridharan, Meera, Go, Ronald S, McCrae, Keith R, Upreti, Harsh Vardhan, Liu, Angela, Lim, Ming Y, Gangaraju, Radhika, Zheng, X Long, Raval, Jay S, Masias, Camila, Cataland, Spero R, Johnson, Andrew, Davis, Elizabeth, Evans, Michael D, Mazepa, Marshall A

“…Immune-mediated thrombotic thrombocytopenic purpura (iTTP) is characterized by recurring episodes of thrombotic microangiopathy, causing ischemic organ…”
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Effect of Hyperoxia on Central Nervous System Intercellular Communication Mediated by Tunneling Nanotubes by Ray, Rupa, Kernagis, Dawn, de Ridder, Gustaaf, Pizzo, Salvatore

“…Abstract only Oxygen toxicity occurs when exposure to elevated partial pressures of oxygen results in hyperoxia. Central nervous system oxygen toxicity…”
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195: RBC REJUVENATION AND BEDSIDE WASHING ATTENUATES HEMOLYSIS IN SIMULATED CARDIOPULMONARY BYPASS by Srinivasan, Amudan, Crabtree, Angela, Ansari, Andrea, Stoner, Keaton, de Ridder, Gustaaf, Gray, Alan, Landrigan, Matthew, Poisson, Jessica, Welsby, Ian

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Abstract 5248: Tunneling nanotubes connect melanoma cells and mediate transfer of mitochondria and GRP78 by de Ridder, Gustaaf G., Ray, Rupa, Pizzo, Salvatore V.

“…Abstract Background: Recently, exciting reports have outlined the existence and function of very thin, membranous conduits between cells that span significant…”
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Abstract 1247: Development of GRP78 scFv-Subtilase fusion proteins for sensitization of melanoma to chemotherapeutics by Ray, Rupa, de Ridder, Gustaaf, Pizzo, Salvatore V.

“…Abstract GRP78 is an important molecular chaperone in the endoplasmic reticulum (ER). However, GRP78 is aberrantly expressed on the surface of melanoma cells…”
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