Search Results - "de Raaf, Michiel A."

Imatinib in patients with severe COVID-19: a randomised, double-blind, placebo-controlled, clinical trial by Aman, Jurjan, Duijvelaar, Erik, Botros, Liza, Kianzad, Azar, Schippers, Job R, Smeele, Patrick J, Azhang, Sara, Bartelink, Imke H, Bayoumy, Ahmed A, Bet, Pierre M, Boersma, Wim, Bonta, Peter I, Boomars, Karin A T, Bos, Lieuwe D J, van Bragt, Job J M H, Braunstahl, Gert-Jan, Celant, Lucas R, Eger, Katrien A B, Geelhoed, J J Miranda, van Glabbeek, Yurika L E, Grotjohan, Hans P, Hagens, Laura A, Happe, Chris M, Hazes, Boaz D, Heunks, Leo M A, van den Heuvel, Michel, Hoefsloot, Wouter, Hoek, Rianne J A, Hoekstra, Romke, Hofstee, Herman M A, Juffermans, Nicole P, Kemper, E Marleen, Kos, Renate, Kunst, Peter W A, Lammers, Ariana, van der Lee, Ivo, van der Lee, E Laurien, Maitland-van der Zee, Anke-Hilse, Mau Asam, Pearl F M, Mieras, Adinda, Muller, Mirte, Neefjes, Elisabeth C W, Nossent, Esther J, Oswald, Laurien M A, Overbeek, Maria J, Pamplona, Carolina C, Paternotte, Nienke, Pronk, Niels, de Raaf, Michiel A, van Raaij, Bas F M, Reijrink, Merlijn, Schultz, Marcus J, Serpa Neto, Ary, Slob, Elise M A, Smeenk, Frank W J M, Smit, Marry R, Smits, A Josien, Stalenhoef, Janneke E, Tuinman, Pieter R, Vanhove, Arthur L E M, Wessels, Jeroen N, van Wezenbeek, Jessie C C, Vonk Noordegraaf, Anton, de Man, Frances S, Bogaard, Harm J

“…The major complication of COVID-19 is hypoxaemic respiratory failure from capillary leak and alveolar oedema. Experimental and early clinical data suggest that…”
Get full text

Nintedanib improves cardiac fibrosis but leaves pulmonary vascular remodelling unaltered in experimental pulmonary hypertension by Rol, Nina, de Raaf, Michiel A, Sun, Xiaoqing Q, Kuiper, Vincent P, da Silva Gonçalves Bos, Denielli, Happé, Chris, Kurakula, Kondababu, Dickhoff, Chris, Thuillet, Raphael, Tu, Ly, Guignabert, Christophe, Schalij, Ingrid, Lodder, Kirsten, Pan, Xiaoke, Herrmann, Franziska E, van Nieuw Amerongen, Geerten P, Koolwijk, Pieter, Vonk-Noordegraaf, Anton, de Man, Frances S, Wollin, Lutz, Goumans, Marie-José, Szulcek, Robert, Bogaard, Harm J

“…Abstract Aims Pulmonary arterial hypertension (PAH) is associated with increased levels of circulating growth factors and corresponding receptors such as…”
Get full text

DNGR1-Cre-mediated Deletion of Tnfaip3 /A20 in Conventional Dendritic Cells Induces Pulmonary Hypertension in Mice by Koudstaal, Thomas, van Hulst, Jennifer A C, Das, Tridib, Neys, Stefan F H, Merkus, Daphne, Bergen, Ingrid M, de Raaf, Michiel A, Bogaard, Harm Jan, Boon, Louis, van Loo, Geert, Aerts, Joachim G J V, Boomars, Karin A, Kool, Mirjam, Hendriks, Rudi W

“…Chronic perivascular inflammation is a prominent feature in the lungs of idiopathic pulmonary arterial hypertension. Although the proportions of conventional…”
Get full text

Placental effects and transfer of sildenafil in healthy and preeclamptic conditions by Hitzerd, Emilie, Broekhuizen, Michelle, Mirabito Colafella, Katrina M., Glisic, Marija, de Vries, René, Koch, Birgit C.P., de Raaf, Michiel A., Merkus, Daphne, Schoenmakers, Sam, Reiss, Irwin K.M., Danser, A.H. Jan, Simons, Sinno H.P.

“…The phosphodiesterase-5 inhibitor (PDE5) sildenafil has emerged as a promising treatment for preeclampsia (PE). However, a sildenafil trial was recently halted…”
Get full text

Agrobacterium-mediated gene transfer and enhanced green fluorescent protein visualization in the mycorrhizal ascomycete Tuber borchii: a first step towards truffle genetics by Grimaldi, B, Raaf, M.A. de, Filetici, P, Ottonello, S, Ballario, P

“…Mycorrhizal ascomycetes are ecologically and commercially important fungi that have proved impervious to genetic transformation so far. We report here on the…”
Get full text

Placental effects and transfer of sildenafil in healthy and preeclamptic conditionsResearch in context by Emilie Hitzerd, Michelle Broekhuizen, Katrina M. Mirabito Colafella, Marija Glisic, René de Vries, Birgit C.P. Koch, Michiel A. de Raaf, Daphne Merkus, Sam Schoenmakers, Irwin K.M. Reiss, A.H. Jan Danser, Sinno H.P. Simons

“…Background: The phosphodiesterase-5 inhibitor (PDE5) sildenafil has emerged as a promising treatment for preeclampsia (PE). However, a sildenafil trial was…”
Get full text