Search Results - "de Pillis, Lisette"

Mesenchymal stem cells used as carrier cells of oncolytic adenovirus results in enhanced oncolytic virotherapy by Mahasa, Khaphetsi Joseph, de Pillis, Lisette, Ouifki, Rachid, Eladdadi, Amina, Maini, Philip, Yoon, A-Rum, Yun, Chae-Ok

“…Mesenchymal stem cells (MSCs) loaded with oncolytic viruses are presently being investigated as a new modality of advanced/metastatic tumors treatment and…”
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A combination therapy of oncolytic viruses and chimeric antigen receptor T cells: a mathematical model proof-of-concept by Mahasa, Khaphetsi Joseph, Ouifki, Rachid, Eladdadi, Amina, Pillis, Lisette de

“…Combining chimeric antigen receptor T (CAR-T) cells with oncolytic viruses (OVs) has recently emerged as a promising treatment approach in preclinical studies…”
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A validated mathematical model of cell-mediated immune response to tumor growth by DE PILLIS, Lisette G, RADUNSKAYA, Ami E, WISEMAN, Charles L

“…Mathematical models of tumor-immune interactions provide an analytic framework in which to address specific questions about tumor-immune dynamics. We present a…”
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Modelling tumour-immune dynamics, disease progression and treatment by Eladdadi, Amina, Pillis, Lisette de, Kim, Peter

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Mathematical model of tumor–immune surveillance by Mahasa, Khaphetsi Joseph, Ouifki, Rachid, Eladdadi, Amina, Pillis, Lisette de

“…We present a novel mathematical model involving various immune cell populations and tumor cell populations. The model describes how tumor cells evolve and…”
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A Role of Effector CD8+ T Cells Against Circulating Tumor Cells Cloaked with Platelets: Insights from a Mathematical Model by Mahasa, Khaphetsi Joseph, Ouifki, Rachid, de Pillis, Lisette, Eladdadi, Amina

“…Cancer metastasis accounts for a majority of cancer-related deaths worldwide. Metastasis occurs when the primary tumor sheds cells into the blood and lymphatic…”
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Natural Killer Cells Recruitment in Oncolytic Virotherapy: A Mathematical Model by Senekal, Noma Susan, Mahasa, Khaphetsi Joseph, Eladdadi, Amina, de Pillis, Lisette, Ouifki, Rachid

“…In this paper, we investigate how natural killer (NK) cell recruitment to the tumor microenvironment (TME) affects oncolytic virotherapy. NK cells play a major…”
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Oncolytic potency and reduced virus tumor-specificity in oncolytic virotherapy. A mathematical modelling approach by Mahasa, Khaphetsi Joseph, Eladdadi, Amina, de Pillis, Lisette, Ouifki, Rachid

“…In the present paper, we address by means of mathematical modeling the following main question: How can oncolytic virus infection of some normal cells in the…”
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A Mathematical Model for DC Vaccine Treatment of Type I Diabetes by Shtylla, Blerta, Gee, Marissa, Do, An, Shabahang, Shahrokh, Eldevik, Leif, de Pillis, Lisette

“…Type I diabetes (T1D) is an autoimmune disease that can be managed, but for which there is currently no cure. Recent discoveries, particularly in mouse models,…”
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Team Research at the Biology–Mathematics Interface: Project Management Perspectives by Milton, John G, Radunskaya, Ami E, Lee, Arthur H, de Pillis, Lisette G, Bartlett, Diana F

“…The success of interdisciplinary research teams depends largely upon skills related to team performance. We evaluated student and team performance for…”
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Multi-method global sensitivity analysis of mathematical models by Dela, An, Shtylla, Blerta, de Pillis, Lisette

“…[Display omitted] •Selecting appropriate parameter sensitivity methods poses significant challenges.•We develop a framework that employs and compares three…”
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Are Engineering Schools Masculine and Authoritarian? The Mission Statements Say Yes by Pillis, Emmeline de, Pillis, Lisette de

“…After reading the mission statements of 20 engineering and liberal arts schools, business students recorded their impressions of a hypothetical successful…”
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A Letter from the Guest Editors by Adler, Fred, Allman, Elizabeth S., de Pillis, Lisette G.

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Toward Integration: From Quantitative Biology to Mathbio-Biomath? by Marsteller, Pat, de Pillis, Lisette, Findley, Ann, Joplin, Karl, Pelesko, John, Nelson, Karen, Thompson, Katerina, Usher, David, Watkins, Joseph

“…In response to the call of "BIO2010" for integrating quantitative skills into undergraduate biology education, 30 Howard Hughes Medical Institute (HHMI)…”
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A Role of Effector CD 8 + T Cells Against Circulating Tumor Cells Cloaked with Platelets: Insights from a Mathematical Model by Mahasa, Khaphetsi Joseph, Ouifki, Rachid, de Pillis, Lisette, Eladdadi, Amina

“…Cancer metastasis accounts for a majority of cancer-related deaths worldwide. Metastasis occurs when the primary tumor sheds cells into the blood and lymphatic…”
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A mathematical model of the within-host kinetics of SARS-CoV-2 neutralizing antibodies following COVID-19 vaccination by dePillis, Lisette, Caffrey, Rebecca, Chen, Ge, Dela, Mark D., Eldevik, Leif, McConnell, Joseph, Shabahang, Shahrokh, Varvel, Stephen A.

“…Compelling evidence continues to build to support the idea that SARS-CoV-2 Neutralizing Antibody (NAb) levels in an individual can serve as an important…”
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Seeking bang-bang solutions of mixed immuno-chemotherapy of tumors by Weiqing Gu, K. Renee Fister, Lisette G. de Pillis

“…It is known that a beneficial cancer treatment approach for a single patient often involves the administration of more than one type of therapy. The question…”
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Modelling Tumour–Immune Dynamics, Disease Progression and Treatment by Eladdadi, Amina, de Pillis, Lisette, Kim, Peter

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Comment on: A Validated Mathematical Model of Cell-Mediated Immune Response to Tumor Growth by de Pillis, Lisette G., Radunskaya, Ami E., Wiseman, Charles L.

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Mathematical Biology at an Undergraduate Liberal Arts College by de Pillis, Lisette, Adolph, Stephen C

“…Since 2002 the authors have offered an undergraduate major in Mathematical Biology at Harvey Mudd College. The major was developed and is administered jointly…”
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