Search Results - "de Oliveira, Catiúscia P."

How Sorbitan Monostearate Can Increase Drug-Loading Capacity of Lipid-Core Polymeric Nanocapsules by Poletto, Fernanda S, De Oliveira, Catiúscia P, Wender, Heberton, Regent, Dorothée, Donida, Bruna, Teixeira, Sérgio R, Guterres, Sílvia S, Rossi-Bergmann, Bartira, Pohlmann, Adriana R

“…Lipid-core polymeric nanocapsules are innovative devices that present distinguished characteristics due to the presence of sorbitan monostearate into the…”
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Enhanced and Selective Antiproliferative Activity of Methotrexate-Functionalized-Nanocapsules to Human Breast Cancer Cells (MCF-7) by de Oliveira, Catiúscia P, Büttenbender, Sabrina L, Prado, Willian A, Beckenkamp, Aline, Asbahr, Ana C, Buffon, Andréia, Guterres, Silvia S, Pohlmann, Adriana R

“…Methotrexate is a folic acid antagonist and its incorporation into nanoformulations is a promising strategy to increase the drug antiproliferative effect on…”
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Methotrexate up-regulates ecto-5′-nucleotidase/CD73 and reduces the frequency of T lymphocytes in the glioblastoma microenvironment by Figueiró, Fabrício, de Oliveira, Catiúscia P., Bergamin, Letícia S., Rockenbach, Liliana, Mendes, Franciane B., Jandrey, Elisa Helena F., Moritz, Cesar Eduardo J., Pettenuzzo, Letícia F., Sévigny, Jean, Guterres, Silvia S., Pohlmann, Adriana R., Battastini, Ana Maria O.

“…Glioblastoma multiforme (GBM) is a deadly cancer characterized by a pro-tumoral immune response. T-regulatory (Treg) lymphocytes suppress effector immune cells…”
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Pharmacological Improvement and Preclinical Evaluation of Methotrexate-Loaded Lipid-Core Nanocapsules in a Glioblastoma Model by Figueiró, Fabrício, de Oliveira, Catiúscia P, Rockenbach, Liliana, Mendes, Franciane B, Bergamin, Letícia S, Jandrey, Elisa Helena F, Edelweiss, Maria Isabel, Guterres, Silvia S, Pohlmann, Adriana R, Battastini, Ana Maria O

“…Glioblastoma multiforme is a devastating cerebral tumor with an exceedingly poor prognosis. Methotrexate (MTX) is a folic acid analogue that inhibits DNA…”
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Mechanisms of the effectiveness of poly(ε-caprolactone) lipid-core nanocapsules loaded with methotrexate on glioblastoma multiforme treatment by Pereira, Natalia Rubio Claret, Loiola, Rodrigo Azevedo, Rodrigues, Stephen Fernandes, de Oliveira, Catiuscia P, Büttenbender, Sabrina L, Guterres, Silvia S, Pohlmann, Adriana R, Farsky, Sandra H

“…The low penetration of drugs across the blood-brain barrier (BBB) compromises the delivery of chemotherapeutic agents to the brain parenchyma and contributes…”
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Radar charts based on particle sizing as an approach to establish the fingerprints of polymeric nanoparticles in aqueous formulations by Bianchin, Mariana D., Külkamp-Guerreiro, Irene C., de Oliveira, Catiuscia P., Contri, Renata Vidor, Guterres, Sílvia S., Pohlmann, Adriana R.

“…Pre-formulation studies are conducted each time new nanoparticulate formulations are in development to the selection of a satisfactory drug delivery system. We…”
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