Search Results - "de Oña Navarrete, Raquel"
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Phase 2 trial of the farnesyltransferase inhibitor tipifarnib for relapsed/refractory peripheral T-cell lymphoma
Published in Blood advances (10-09-2024)“…•The oral farnesyltransferase inhibitor, tipifarnib, as a single agent, produces responses in 40% of patients with heavily pretreated PTCL.•Biomarker…”
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Bendamustine for Mantle Cell Lymphoma: Retrospective Analysis of the Spanish Experience
Published in Blood (18-11-2011)“…Abstract 4942 Patients with Mantle cell lymphoma (MCL) have an adverse outcome after relapse due to chemorefractory disease with conventional treatments…”
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Inherited Thrombocytopenias Predisposing to Hematologic Neoplasms. Experience of the Spanish Group for Inherited Platelet Disorders (GEAPC)
Published in Blood (02-11-2023)“…Introduction In inherited thrombocytopenic disorders (IT) associated with germline genetic variants in the transcription factors RUNX1 (RUNX1-RT) and ETV6…”
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Tipifarnib in Relapsed or Refractory Angioimmunoblastic T-Cell Lymphoma (AITL) and CXCL12+ Peripheral T-Cell Lymphoma (PTCL): Preliminary Results from an Open-Label, Phase 2 Study
Published in Blood (29-11-2018)“…Background Tipifarnib is a potent and selective inhibitor of the enzyme farnesyltransferase (FT). FT catalyzes post-translational attachment of farnesyl groups…”
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Journal Article