Search Results - "de Nisco, Giuseppe"
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The definition of low wall shear stress and its effect on plaque progression estimation in human coronary arteries
Published in Scientific reports (11-11-2021)“…Wall shear stress (WSS), the frictional force of the blood on the vessel wall, plays a crucial role in atherosclerotic plaque development. Low WSS has been…”
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Wall Shear Stress Topological Skeleton Independently Predicts Long-Term Restenosis After Carotid Bifurcation Endarterectomy
Published in Annals of biomedical engineering (01-12-2020)“…Wall Shear Stress (WSS) topological skeleton, composed by fixed points and the manifolds linking them, reflects the presence of blood flow features associated…”
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Multidirectional wall shear stress promotes advanced coronary plaque development: comparing five shear stress metrics
Published in Cardiovascular research (01-05-2020)“…Abstract Aims Atherosclerotic plaque development has been associated with wall shear stress (WSS). However, the multidirectionality of blood flow, and thus of…”
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Early Atherosclerotic Changes in Coronary Arteries are Associated with Endothelium Shear Stress Contraction/Expansion Variability
Published in Annals of biomedical engineering (01-09-2021)“…Although unphysiological wall shear stress (WSS) has become the consensus hemodynamic mechanism for coronary atherosclerosis, the complex biomechanical…”
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Deciphering ascending thoracic aortic aneurysm hemodynamics in relation to biomechanical properties
Published in Medical engineering & physics (01-08-2020)“…•Spatiotemporal hemodynamic heterogeneity was quantified in ATAA and healthy aortas.•Intravascular flow spatiotemporal heterogeneity influences the WSS…”
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A Eulerian method to analyze wall shear stress fixed points and manifolds in cardiovascular flows
Published in Biomechanics and modeling in mechanobiology (01-10-2020)“…Based upon dynamical systems theory, a fixed point of a vector field such as the wall shear stress (WSS) at the luminal surface of a vessel is a point where…”
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Current and Future Applications of Computational Fluid Dynamics in Coronary Artery Disease
Published in Reviews in cardiovascular medicine (01-11-2022)“…Hemodynamics interacts with the cellular components of human vessels, influencing function and healthy status. Locally acting hemodynamic forces have been…”
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Wall Shear Stress Topological Skeleton Analysis in Cardiovascular Flows: Methods and Applications
Published in Mathematics (Basel) (01-04-2021)“…A marked interest has recently emerged regarding the analysis of the wall shear stress (WSS) vector field topological skeleton in cardiovascular flows. Based…”
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Comparison of Swine and Human Computational Hemodynamics Models for the Study of Coronary Atherosclerosis
Published in Frontiers in bioengineering and biotechnology (02-08-2021)“…Coronary atherosclerosis is a leading cause of illness and death in Western World and its mechanisms are still non completely understood. Several animal models…”
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A reduced-order model-based study on the effect of intermittent pneumatic compression of limbs on the cardiovascular system
Published in Proceedings of the Institution of Mechanical Engineers. Part H, Journal of engineering in medicine (01-04-2016)“…This work investigates the effect that the application of intermittent pneumatic compression to lower limbs has on the cardiovascular system. Intermittent…”
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Finite Element Modeling Application in Forensic Practice: A Periprosthetic Femoral Fracture Case Study
Published in Frontiers in bioengineering and biotechnology (23-06-2020)“…The incidence of periprosthetic fractures has rapidly increased in the last two decades and has been the cause of a large number of revision surgeries and…”
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Design of innovative self-expandable femoral stents using inverse homogenization topology optimization
Published in Computer methods in applied mechanics and engineering (01-11-2023)Get full text
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The Atheroprotective Nature of Helical Flow in Coronary Arteries
Published in Annals of biomedical engineering (01-02-2019)“…Arterial hemodynamics is markedly characterized by the presence of helical flow patterns. Previous observations suggest that arterial helical blood flow is of…”
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Impact of wall displacements on the large-scale flow coherence in ascending aorta
Published in Journal of biomechanics (01-06-2023)“…In the context of aortic hemodynamics, uncertainties affecting blood flow simulations hamper their translational potential as supportive technology in clinics…”
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The impact of helical flow on coronary atherosclerotic plaque development
Published in Atherosclerosis (01-05-2020)“…Atherosclerosis has been associated with near-wall hemodynamics and wall shear stress (WSS). However, the role of coronary intravascular hemodynamics, in…”
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Corrigendum to "Impact of wall displacements on the large-scale flow coherence in ascending aorta" [J. Biomech. 154 (2023) 111620]
Published in Journal of biomechanics (01-11-2023)Get full text
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Modelling blood flow in coronary arteries: Newtonian or shear-thinning non-Newtonian rheology?
Published in Computer methods and programs in biomedicine (01-12-2023)“…•Assumptions on blood rheology have negligible impact on CFD hemodynamic quantities linked to atherosclerotic coronary artery disease.•WSS and helical flow…”
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Predicting Lipid-Rich Plaque Progression in Coronary Arteries Using Multimodal Imaging and Wall Shear Stress Signatures
Published in Arteriosclerosis, thrombosis, and vascular biology (01-04-2024)“…Plaque composition and wall shear stress (WSS) magnitude act as well-established players in coronary plaque progression. However, WSS magnitude per se does not…”
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Coronary Artery Stenting Affects Wall Shear Stress Topological Skeleton
Published in Journal of biomechanical engineering (01-06-2022)“…Despite the important advancements in the stent technology for the treatment of diseased coronary arteries, major complications still affect the postoperative…”
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Smartphone-based particle tracking velocimetry for the in vitro assessment of coronary flows
Published in Medical engineering & physics (01-04-2024)“…•Smartphone-based setup allows particle tracking velocimetry of coronary flows.•The setup is sustainable, versatile, easy to use, safe and low-cost.•Lagrangian…”
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