Search Results - "de Munter, Johannes"
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Neuro‐Cells therapy improves motor outcomes and suppresses inflammation during experimental syndrome of amyotrophic lateral sclerosis in mice
Published in CNS neuroscience & therapeutics (01-05-2020)“…Aims Mutations in DNA/RNA‐binding factor (fused‐in‐sarcoma) FUS and superoxide dismutase‐1 (SOD‐1) cause amyotrophic lateral sclerosis (ALS). They were…”
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Stem cell grafting in parkinsonism – Why, how and when
Published in Parkinsonism & related disorders (01-01-2014)“…Summary Parkinson's disease is a devastating, progressive neurodegenerative disorder that affects the central and peripheral nervous systems. Although recent…”
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Tauroursodeoxycholic Acid Reduces Neuroinflammation but Does Not Support Long Term Functional Recovery of Rats with Spinal Cord Injury
Published in Biomedicines (25-06-2022)“…The bile acid tauroursodeoxycholic acid (TUDCA) reduces cell death under oxidative stress and inflammation. Implants of bone marrow-derived stromal cells…”
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70th Birthday symposium of Prof. Dr. Riederer: autologous adult stem cells in ischemic and traumatic CNS disorders
Published in Journal of Neural Transmission (2013)“…Ischemic and traumatic insults of the central nervous system both result in definite chronic disability, only to some extent responsive to rehabilitation…”
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Autologous stem cells in neurology: is there a future?
Published in Journal of Neural Transmission (2013)“…Stem cells seem very promising in the treatment of degenerative neurological diseases for which there are currently no or limited therapeutic strategies…”
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Cell based therapy in Parkinsonism
Published in Translational neurodegeneration (04-06-2013)“…Parkinson's disease (PD) is a synucleinopathy-induced chronic progressive neurodegenerative disorder, worldwide affecting about 5 million humans. As of yet,…”
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Treatment of rats with spinal cord injury using human bone marrow-derived stromal cells prepared by negative selection
Published in Journal of biomedical science (18-02-2020)“…Spinal cord injury (SCI) is a highly debilitating pathology without curative treatment. One of the most promising disease modifying strategies consists in the…”
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Aberrant Ganglioside Functions to Underpin Dysregulated Myelination, Insulin Signalling, and Cytokine Expression: Is There a Link and a Room for Therapy?
Published in Biomolecules (Basel, Switzerland) (01-10-2022)“…Gangliosides are molecules widely present in the plasma membranes of mammalian cells, participating in a variety of processes, including protein organization,…”
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Increased Oxidative Stress in the Prefrontal Cortex as a Shared Feature of Depressive- and PTSD-Like Syndromes: Effects of a Standardized Herbal Antioxidant
Published in Frontiers in nutrition (Lausanne) (15-04-2021)“…Major depression (MD) and posttraumatic stress disorder (PTSD) share common brain mechanisms and treatment strategies. Nowadays, the dramatically developing…”
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Immunomodulatory effects of new phytotherapy on human macrophages and TLR4- and TLR7/8-mediated viral-like inflammation in mice
Published in Frontiers in medicine (22-08-2022)“…While all efforts have been undertaken to propagate the vaccination and develop remedies against SARS-CoV-2, no satisfactory management of this infection is…”
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Molecular and behavioural abnormalities in the FUS‐tg mice mimic frontotemporal lobar degeneration: Effects of old and new anti‐inflammatory therapies
Published in Journal of cellular and molecular medicine (01-09-2020)“…Genetic mutations in FUS, a DNA/RNA‐binding protein, are associated with inherited forms of frontotemporal lobar degeneration (FTLD) and amyotrophic lateral…”
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Inside Front Cover
Published in CNS neuroscience & therapeutics (01-05-2020)Get full text
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