Search Results - "de Muinck, Ebo D."

Quantitative fat and R2 mapping in vivo to measure lipid‐rich necrotic core and intraplaque hemorrhage in carotid atherosclerosis by Koppal, Sandeep, Warntjes, Marcel, Swann, Jeremy, Dyverfeldt, Petter, Kihlberg, Johan, Moreno, Rodrigo, Magee, Derek, Roberts, Nicholas, Zachrisson, Helene, Forssell, Claes, Länne, Toste, Treanor, Darren, de Muinck, Ebo D

“…Purpose The aim of this work was to quantify the extent of lipid‐rich necrotic core (LRNC) and intraplaque hemorrhage (IPH) in atherosclerotic plaques. Methods…”
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Copper Chelation Represses the Vascular Response to Injury by Mandinov, Lazar, Mandinova, Anna, Kyurkchiev, Stanimir, Kyurkchiev, Dobroslav, Kehayov, Ivan, Kolev, Vihren, Soldi, Raffaella, Bagala, Cinzia, de Muinck, Ebo D., Lindner, Volkhard, Post, Mark J., Simons, Michael, Bellum, Stephen, Prudovsky, Igor, Maciag, Thomas

“…The induction of an acute inflammatory response followed by the release of polypeptide cytokines and growth factors from peripheral blood monocytes has been…”
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Humoral and Cellular Factors Responsible for Coronary Collateral Formation by Sherman, Jonathan A., Hall, Amy, Malenka, David J., De Muinck, Ebo D., Simons, Michael

“…Clinical observations suggest that patients with coronary artery disease (CAD) display a marked heterogenerty in collateral formation despite similar degrees…”
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Value of the electrocardiogram in localizing the occlusion site in the left anterior descending coronary artery in acute anterior myocardial infarction by Engelen, Domien J, Gorgels, Anton P, Cheriex, Emile C, De Muinck, Ebo D, Oude Ophuis, Anton J, Dassen, Willem R, Vainer, Jindra, van Ommen, Vincent G, Wellens, Hein J

“…OBJECTIVES The study assessed the value of the electrocardiogram (ECG) as predictor of the left anterior descending coronary artery (LAD) occlusion site in…”
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Prognostic value of coronary blood flow velocity and myocardial perfusion in intermediate coronary narrowings and multivessel disease by Chamuleau, Steven A.J., Tio, Rene A., de Cock, Carel C., de Muinck, Ebo D., Pijls, Nico H.J., van Eck-Smit, Berthe L.F., Koch, Karel T., Meuwissen, Martijn, Dijkgraaf, Marcel G.W., de Jong, Angelina, Verberne, Hein J., van Liebergen, Rob A.M., Laarman, Gert Jan, Tijssen, Jan G.P., Piek, Jan J.

“…This study aimed to investigate the roles of intracoronary derived coronary flow velocity reserve (CFVR) and myocardial perfusion scintigraphy (single photon…”
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Approaches to Multimodality Imaging of Angiogenesis by Dobrucki, Lawrence W, de Muinck, Ebo D, Lindner, Jonathan R, Sinusas, Albert J

“…Angiogenesis, defined as the formation of new capillaries by cellular outgrowth from existing microvessels, can be assessed by the evaluation of perfusion,…”
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Fractional flow reserve to determine the appropriateness of angioplasty in moderate coronary stenosis: A randomized trial by WILLEM BECH, G. Jan, DE BRUYNE, Bernard, WIJNS, William, PIJLS, Nico H. J, DE MUINCK, Ebo D, HOORNTJE, Jan C. A, ESCANED, Javier, STELLA, Pieter R, BOERSMA, Eric, BARTUNEK, Jozef, KOOLEN, Jacques J

“…PTCA of a coronary stenosis without documented ischemia at noninvasive stress testing is often performed, but its benefit is unproven. Coronary…”
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Requirement for CD154 in the progression of atherosclerosis by Daemen, Mat J.A.P, Lutgens, Esther, Gorelik, Leonid, de Muinck, Ebo D, Grewal, Iqbal S, Koteliansky, Victor E, Flavell, Richard A

“…Atherosclerosis is a systemic disease of the large arteries, and activation of inflammatory pathways is important in its pathogenesis. Increasing evidence…”
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Gene and cell therapy for heart failure by de Muinck, Ebo D

“…Cardiac gene and cell therapy have both entered clinical trials aimed at ameliorating ventricular dysfunction in patients with chronic congestive heart…”
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cNGR: A Novel Homing Sequence for CD13/APN Targeted Molecular Imaging of Murine Cardiac Angiogenesis In Vivo by Buehler, Alexandra, van Zandvoort, Marc A.M.J, Stelt, Bram J, Hackeng, Tilman M, Schrans-Stassen, Bianca H.G.J, Bennaghmouch, Abdelkader, Hofstra, Leo, Cleutjens, Jack P.M, Duijvestijn, Adriaan, Smeets, Mirjam B, de Kleijn, Dominique P.V, Post, Mark J, de Muinck, Ebo D

“…OBJECTIVE—Previously, the peptide sequence cNGR has been shown to home specifically to CD13/APN (aminopeptidase N) on tumor endothelium. Here, we investigated…”
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Arteriogenesis: noninvasive quantification with multi-detector row CT angiography and three-dimensional volume rendering in rodents by Zhuang, Zhen W, Gao, Ling, Murakami, Masahiro, Pearlman, Justin D, Sackett, Terry J, Simons, Michael, de Muinck, Ebo D

“…To evaluate two-dimensional (2D) multi-detector row computed tomographic (CT) angiography and three-dimensional (3D) volume rendering for depiction of patterns…”
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Calling on reserves: granulocyte colony stimulating growth factor in cardiac repair by de Muinck, Ebo D, Simons, Michael

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Atherosclerosis in APOE3-Leiden transgenic mice: From proliferative to atheromatous stage by LUTGENS, E, DAEMEN, M, KOCKX, M, DOEVENDANS, P, HOFKER, M, HAVEKES, L, WELLENS, H, DE MUINCK, E. D

“…This study documents (1) the progression of atherosclerosis along the entire arterial tree in APOE*3-Leiden mice after 1, 4, 6, 9, and 12 months of a…”
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Live 3D echo guidance of catheter-based endomyocardial injection by Baklanov, Dmitri V., de Muinck, Ebo D., Simons, Michael, Moodie, Karen L., Arbuckle, Brenda E., Thompson, Craig A., Palac, Robert T.

“…Local delivery of therapeutic agents into the myocardium is limited by suboptimal imaging. We evaluated the feasibility and accuracy of live 3D echo to guide…”
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Compensatory Enlargement and Stenosis Develop in ApoE−/− and ApoE3-Leiden Transgenic Mice by Lutgens, Esther, de Muinck, Ebo D, Heeneman, Sylvia, Daemen, Mat J.A.P

“…Atherosclerotic mouse models develop little ischemic organ damage and no infarctions, despite the presence of large atherosclerotic lesions. Therefore, we…”
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Endothelial Nitric Oxide Synthase Is Critical for Ischemic Remodeling, Mural Cell Recruitment, and Blood Flow Reserve by Yu, Jun, deMuinck, Ebo D., Zhuang, Zhenwu, Drinane, Mary, Kauser, Katalin, Rubanyi, Gabor M., Qian, Hu Sheng, Murata, Takahisa, Escalante, Bruno, Sessa, William C., Ignarro, Louis J.

“…The genetic loss of endothelial-derived nitric oxide synthase (eNOS) in mice impairs vascular endothelial growth factor (VEGF) and ischemia-initiated blood…”
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Abstract 20143: Direct in vivo Quantification of Intraplaque Hemorrhage and Fat in Atherosclerosis by Magnetic Resonance Imaging by Koppal, Sandeep, Warntjes, Marcel, Swann, Jeremy, Dyverfeldt, Petter, Kihlberg, Johan, Moreno, Rodrigo, Magee, Derek, Roberts, Nicholas, Treanor, Darren, de Muinck, Ebo D

“…Abstract only Introduction: Intraplaque hemorrhage (IPH) and lipid core (LC) are hallmarks of rupture-prone atherosclerotic plaque. HYPOTHESIS: We hypothesized…”
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Biphasic pattern of cell turnover characterizes the progression from fatty streaks to ruptured human atherosclerotic plaques by Lutgens, E, de Muinck, E D, Kitslaar, P J, Tordoir, J H, Wellens, H J, Daemen, M J

“…To study the amount and phenotype of DNA-synthesizing and apoptotic cells during atherogenesis. Atherosclerotic lesions (n = 76), obtained at autopsy (N = 6)…”
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Chronic myocardial infarction in the mouse : cardiac structural and functional changes by LUTGENS, E, DAEMEN, M. J. A. P, DE MUINCK, E. D, DEBETS, J, LEENDERS, P, SMITS, J. F. M

“…We studied the effects of chronic left coronary artery ligation on cardiac structure and function in the mouse. Morphometric studies of the left ventricle were…”
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Cardiovascular phenotyping in mice by DOEVENDANS, P. A, DAEMEN, M. J, DE MUINCK, E. D, SMITS, J. F

“…Progress in molecular genetics has changed cardiovascular research. The mouse has turned out to be an invaluable model for mammalian genetic modifications to…”
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