Search Results - "de Moura, Ricardo O"

Antitumor Effect of a Novel Spiro-Acridine Compound is Associated with Up-Regulation of Th1-Type Responses and Antiangiogenic Action by Silva, Daiana K Frade, Duarte, Sâmia S, Lisboa, Thaís M H, Ferreira, Rafael C, Lopes, Ana Luíza de O, Carvalho, Deyse C M, Rodrigues-Mascarenhas, Sandra, da Silva, Patricia Mirella, Segundo, Miguel A S Pinheiro, Moura, Ricardo O de, Medeiros, Karina C P, Sobral, Marianna V

“…Tumor cells have specific features, including angiogenesis induction, cell cycle dysregulation, and immune destruction evasion. By inducing a T helper type 2…”
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Multi-Target Drugs for Neglected Diseases by Scotti, Luciana, Filho, Francisco J B M, de Moura, Ricardo O, Ribeiro, Frederico F, Ishiki, Hamilton, da Silva, Marcelo S, Filho, José M B, Scotti, Marcus T

“…Diseases perceived as neglected tropical infections are generally caused by parasites which reach poor, underserved populations (primarily infrastructure),…”
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Synthesis and preliminary ex vivo evaluation of the spasmolytic activity of 1,3-thiazolium- and 1,3,4-thiadiazolium-5-methylthio- and 5-thioacetate derivatives by Luis, José A. S., Aquino, Thiago M. De, Lira, Bruno F., Filho, Petrônio F. A., Scotti, Marcus T., Scotti, Luciana, Moura, Ricardo O. De, Junior, Francisco J. B. Mendonça

“…Seven new compounds have been synthetized in satisfactory yields (51-78 %) through the treatment of mesoionic 1,3-thiazolium-5-thiolate (4a-d) and…”
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Bioprospecting of Nitrogenous Heterocyclic Scaffolds with Potential Action for Neglected Parasitosis: A Review by Albino, Sonaly L, da Silva, Jamire M, de C Nobre, Michelangela S, de M E Silva, Yvnni M S, Santos, Mirelly B, de Araújo, Rodrigo S A, do C A de Lima, Maria, Schmitt, Martine, de Moura, Ricardo O

“…Neglected parasitic diseases are a group of infections currently considered as a worldwide concern. This fact can be attributed to the migration of these…”
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Synthesis and Evaluation of Antiproliferative Activity, Topoisomerase IIα Inhibition, DNA Binding and Non-Clinical Toxicity of New Acridine–Thiosemicarbazone Derivatives by Sousa, Gleyton, de Almeida, Maria C. F, Lócio, Lucas L, dos Santos, Vanda L, Bezerra, Daniel P, Silva, Valdenizia R, de Almeida, Sinara M. V, Simon, Alice, Honório, Thiago da S, Cabral, Lucio M, Castro, Rosane N, de Moura, Ricardo O, Kümmerle, Arthur E

“…In this study, we report the synthesis of twenty new acridine–thiosemicarbazone derivatives and their antiproliferative activities. Mechanisms of action such…”
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Synthesis and Anticancer Evaluation of Thiazacridine Derivatives Reveals New Selective Molecules to Hematopoietic Neoplastic Cells by de Melo Rego, Moacyr J B, de Sena, Wanessa L B, de Moura, Ricardo O, Jacob, Iris T T, Lins E Lins, Thiago U, Pereira, Michelly C, do Carmo A Lima, Maria, Galdino-Pitta, Marina R, da R Pitta, Ivan, da Rocha Pitta, Maira G

“…Cancer has become one of the leading causes of morbidity and mortality worldwide. Limitations associated with existing agents increase the need to develop more…”
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Correlation between DNA/HSA-interactions and antimalarial activity of acridine derivatives: Proposing a possible mechanism of action by de M. Silva, Marina, Macedo, Taís S., Teixeira, Helena Mariana P., Moreira, Diogo Rodrigo M., Soares, Milena B.P., da C. Pereira, Ana Ligia, de L. Serafim, Vanessa, Mendonça-Júnior, Francisco J.B., do Carmo A. de Lima, Maria, de Moura, Ricardo O., da Silva-Júnior, Edeildo F., de Araújo-Júnior, João Xavier, de A. Dantas, Maria Dayanne, de O. O. Nascimento, Eduarda, Maciel, Thamilla Maria S., de Aquino, Thiago Mendonça, Figueiredo, Isis M., Santos, Josué C.C.

“…Acridines are considered an important class of compounds due to their wide variety of biological activities. In this work, we synthesized four acridine…”
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Synthesis, structure-activity relationships (SAR) and in silico studies of coumarin derivatives with antifungal activity by de Araújo, Rodrigo S A, Guerra, Felipe Q S, de O Lima, Edeltrudes, de Simone, Carlos A, Tavares, Josean F, Scotti, Luciana, Scotti, Marcus T, de Aquino, Thiago M, de Moura, Ricardo O, Mendonça, Francisco J B, Barbosa-Filho, José M

“…The increased incidence of opportunistic fungal infections, associated with greater resistance to the antifungal drugs currently in use has highlighted the…”
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C-KIT Receptor Inhibition as a Promising Approach to Design Anticancer Drugs by Dos Santos Nascimento, Igor José, de Moura, Ricardo Olimpio

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