Small Mammals as Carriers/Hosts of Leptospira spp . in the Western Amazon Forest

is a bacteria that causes leptospirosis and is transmitted through water, soil, or mud that is contaminated by the urine of infected animals. Although it is mainly associated with the urban environment, Leptospires also circulate in rural and wild environments. This study aimed to investigate the ro...

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Published in:	Frontiers in veterinary science Vol. 7; p. 569004
Main Authors:	Medeiros, Luciana Dos Santos, Braga Domingos, Susan Christina, Azevedo, Maria Isabel Nogueira Di, Peruquetti, Rui Carlos, de Albuquerque, Narianne Ferreira, D'Andrea, Paulo Sérgio, Botelho, André Luis de Moura, Crisóstomo, Charle Ferreira, Vieira, Anahi Souto, Martins, Gabriel, Teixeira, Bernardo Rodrigues, Carvalho-Costa, Filipe Anibal, Lilenbaum, Walter
Format:	Journal Article
Language:	English
Published:	Switzerland Frontiers Media S.A 02-12-2020
Subjects:	Amazon marsupial small mammal sylvatic leptospirosis Veterinary Science wild rodent small mammal marsupial Amazon wild rodent sylvatic leptospirosis
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Summary:	is a bacteria that causes leptospirosis and is transmitted through water, soil, or mud that is contaminated by the urine of infected animals. Although it is mainly associated with the urban environment, Leptospires also circulate in rural and wild environments. This study aimed to investigate the role of small mammals in leptospirosis epidemiology in the western Amazon, Brazil. In total, 103 animals from 23 species belonging to the orders Didelphimorphia and Rodentia were captured. Blood, kidney, and urine samples were collected and Microscopic Agglutination Test (MAT), L32 PCR, Y sequencing, and culturing were conducted. MAT was reactive on 1/15 sera, and no bacterial isolate was obtained. PCR yielded 44.7% positive samples from 16 species. Twenty samples were genetically characterized and identified as ( = 12), ( = 4), and ( = 4). No statistical association was found between the prevalence of infection by spp. in small mammals within carrier/hosts species, orders, study area, and forest strata. Our results indicate a high prevalence of pathogenic spp. in several rodent and marsupial species and report the first evidence of spp. carrier/hosts in the Brazilian Western Amazon.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 This article was submitted to Veterinary Infectious Diseases, a section of the journal Frontiers in Veterinary Science Reviewed by: André Alex Grassmann, University of Connecticut Health Center, United States; Sharon Yvette Angelina Manalo Villanueva, University of the Philippines Manila, Philippines; Vanina Guernier, USDA APHIS Veterinary Services, United States Edited by: Lester J. Perez, University of Illinois at Urbana–Champaign, United States
ISSN:	2297-1769 2297-1769
DOI:	10.3389/fvets.2020.569004