Search Results - "de Moura, Alessandro P.S"

The dynamics of genome replication using deep sequencing by Müller, Carolin A, Hawkins, Michelle, Retkute, Renata, Malla, Sunir, Wilson, Ray, Blythe, Martin J, Nakato, Ryuichiro, Komata, Makiko, Shirahige, Katsuhiko, de Moura, Alessandro P S, Nieduszynski, Conrad A

“…Eukaryotic genomes are replicated from multiple DNA replication origins. We present complementary deep sequencing approaches to measure origin location and…”
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Mathematical modelling of whole chromosome replication by de Moura, Alessandro P.S, Retkute, Renata, Hawkins, Michelle, Nieduszynski, Conrad A

“…All chromosomes must be completely replicated prior to cell division, a requirement that demands the activation of a sufficient number of appropriately…”
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Stochastic association of neighboring replicons creates replication factories in budding yeast by Saner, Nazan, Karschau, Jens, Natsume, Toyoaki, Gierlinski, Marek, Retkute, Renata, Hawkins, Michelle, Nieduszynski, Conrad A, Blow, J Julian, de Moura, Alessandro P S, Tanaka, Tomoyuki U

“…Inside the nucleus, DNA replication is organized at discrete sites called replication factories, consisting of DNA polymerases and other replication proteins…”
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High-Resolution Replication Profiles Define the Stochastic Nature of Genome Replication Initiation and Termination by Hawkins, Michelle, Retkute, Renata, Müller, Carolin A., Saner, Nazan, Tanaka, Tomoyuki U., de Moura, Alessandro P.S., Nieduszynski, Conrad A.

“…Eukaryotic genome replication is stochastic, and each cell uses a different cohort of replication origins. We demonstrate that interpreting high-resolution…”
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Oxygen-Driven Tumour Growth Model: A Pathology-Relevant Mathematical Approach by Delgado-SanMartin, Juan A, Hare, Jennifer I, de Moura, Alessandro P S, Yates, James W T

“…Xenografts--as simplified animal models of cancer-differ substantially in vasculature and stromal architecture when compared to clinical tumours. This makes…”
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Are the fractal skeletons the explanation for the narrowing of arteries due to cell trapping in a disturbed blood flow? by Schelin, Adriane B, Károlyi, György, de Moura, Alessandro P.S, Booth, Nuala, Grebogi, Celso

“…Abstract We show that common circulatory diseases, such as stenoses and aneurysms, generate chaotic advection of blood particles. This phenomenon has major…”
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Fractal basins in Hénon–Heiles and other polynomial potentials by de Moura, Alessandro P.S, Letelier, Patricio S

“…The dynamics of several Hamiltonian systems of two degrees of freedom with polynomial potentials is examined. All these systems present unbounded trajectories…”
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Frontiers of chaotic advection by Aref, Hassan, Blake, John R., Budišić, Marko, Cardoso, Silvana S. S., Cartwright, Julyan H. E., Clercx, Herman J. H., El Omari, Kamal, Feudel, Ulrike, Golestanian, Ramin, Gouillart, Emmanuelle, van Heijst, GertJan F., Krasnopolskaya, Tatyana S., Le Guer, Yves, MacKay, Robert S., Meleshko, Vyacheslav V., Metcalfe, Guy, Mezić, Igor, de Moura, Alessandro P. S., Piro, Oreste, Speetjens, Michel F. M., Sturman, Rob, Thiffeault, Jean-Luc, Tuval, Idan

“…This work reviews the present position of and surveys future perspectives in the physics of chaotic advection: the field that emerged three decades ago at the…”
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Fractal escapes in Newtonian and relativistic multipole gravitational fields by de Moura, Alessandro P.S, Letelier, Patricio S

“…We study the planar motion of test particles in gravitational fields produced by an external material halo. Both the Newtonian and the general-relativistic…”
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Integrative Model of Oxidative Stress Adaptation in the Fungal Pathogen Candida albicans by Komalapriya, Chandrasekaran, Kaloriti, Despoina, Tillmann, Anna T, Yin, Zhikang, Herrero-de-Dios, Carmen, Jacobsen, Mette D, Belmonte, Rodrigo C, Cameron, Gary, Haynes, Ken, Grebogi, Celso, de Moura, Alessandro P S, Gow, Neil A R, Thiel, Marco, Quinn, Janet, Brown, Alistair J P, Romano, M Carmen

“…The major fungal pathogen of humans, Candida albicans, mounts robust responses to oxidative stress that are critical for its virulence. These responses…”
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Integrated stress response of Escherichia coli to methylglyoxal: transcriptional readthrough from the nemRA operon enhances protection through increased expression of glyoxalase I by Ozyamak, Ertan, Almeida, Camila, Moura, Alessandro P. S., Miller, Samantha, Booth, Ian R.

“…Summary Methylglyoxal (MG) elicits activation of K+ efflux systems to protect cells against the toxicity of the electrophile. ChIP‐chip targeting RNA…”
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Combinatorial stresses kill pathogenic Candida species by Kaloriti, Despoina, Tillmann, Anna, Cook, Emily, Jacobsen, Mette, You, Tao, Lenardon, Megan, Ames, Lauren, Barahona, Mauricio, Chandrasekaran, Komelapriya, Coghill, George, Goodman, Daniel, Gow, Neil A. R., Grebogi, Celso, Ho, Hsueh-Lui, Ingram, Piers, McDonagh, Andrew, de Moura, Alessandro P. S., Pang, Wei, Puttnam, Melanie, Radmaneshfar, Elahe, Romano, Maria Carmen, Silk, Daniel, Stark, Jaroslav, Stumpf, Michael, Thiel, Marco, Thorne, Thomas, Usher, Jane, Yin, Zhikang, Haynes, Ken, Brown, Alistair J. P.

“…Pathogenic microbes exist in dynamic niches and have evolved robust adaptive responses to promote survival in their hosts. The major fungal pathogens of…”
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Reacting particles in open chaotic flows by de Moura, Alessandro P S

“…We study the collision probability p of particles advected by open flows with chaotic advection. We show that p scales with the particle size (or,…”
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Optimal placement of origins for DNA replication by Karschau, Jens, Blow, J Julian, de Moura, Alessandro P S

“…DNA replication is an essential process in biology and its timing must be robust so that cells can divide properly. Random fluctuations in the formation of…”
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Diffusion in randomly perturbed dissipative dynamics by Rodrigues, Christian S., Chechkin, Aleksei V., de Moura, Alessandro P. S., Grebogi, Celso, Klages, Rainer

“…Dynamical systems having many coexisting attractors present interesting properties from both fundamental theoretical and modelling points of view. When such…”
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Strange eigenmodes and chaotic advection in open fluid flows by de Moura, Alessandro P. S.

“…We study the dynamics of mixing of advected fields in open chaotic flows. We propose the eigenfunctions of the stroboscopic advection-diffusion (SAD) operator…”
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Traffic of particles in complex networks by Germano, Renato, de Moura, Alessandro P S

“…The study of the information flow through communication networks, such as the Internet, is of great importance. In the Internet, information flows in discrete…”
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A Matter of Life or Death: Modeling DNA Damage and Repair in Bacteria by Karschau, Jens, de Almeida, Camila, Richard, Morgiane C., Miller, Samantha, Booth, Ian R., Grebogi, Celso, de Moura, Alessandro P.S.

“…DNA damage is a hazard all cells must face, and evolution has created a number of mechanisms to repair damaged bases in the chromosome. Paradoxically, many of…”
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Dynamical collapse of trajectories by Biemond, J. J. Benjamin, de Moura, Alessandro P. S., Grebogi, Celso, van de Wouw, Nathan, Nijmeijer, Henk

“…Friction induces unexpected dynamical behaviour. In the paradigmatic pendulum and double-well systems with friction, modelled with differential inclusions,…”
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Signatures of small-world and scale-free properties in large computer programs by de Moura, Alessandro P S, Lai, Ying-Cheng, Motter, Adilson E

“…A large computer program is typically divided into many hundreds or even thousands of smaller units, whose logical connections define a network in a natural…”
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