Search Results - "de Moura, Alessandro P. S"
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Gene length as a regulator for ribosome recruitment and protein synthesis: theoretical insights
Published in Scientific reports (12-12-2017)“…Protein synthesis rates are determined, at the translational level, by properties of the transcript’s sequence. The efficiency of an mRNA can be tuned by…”
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Integrated stress response of Escherichia coli to methylglyoxal: transcriptional readthrough from the nemRA operon enhances protection through increased expression of glyoxalase I
Published in Molecular microbiology (01-06-2013)“…Summary Methylglyoxal (MG) elicits activation of K+ efflux systems to protect cells against the toxicity of the electrophile. ChIP‐chip targeting RNA…”
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Integrative Model of Oxidative Stress Adaptation in the Fungal Pathogen Candida albicans
Published in PloS one (14-09-2015)“…The major fungal pathogen of humans, Candida albicans, mounts robust responses to oxidative stress that are critical for its virulence. These responses…”
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Fractal structures in stenoses and aneurysms in blood vessels
Published in Philosophical transactions of the Royal Society of London. Series A: Mathematical, physical, and engineering sciences (28-12-2010)“…Recent advances in the field of chaotic advection provide the impetus to revisit the dynamics of particles transported by blood flow in the presence of vessel…”
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Mathematical modelling of whole chromosome replication
Published in Nucleic acids research (01-09-2010)“…All chromosomes must be completely replicated prior to cell division, a requirement that demands the activation of a sufficient number of appropriately…”
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Stochastic association of neighboring replicons creates replication factories in budding yeast
Published in The Journal of cell biology (30-09-2013)“…Inside the nucleus, DNA replication is organized at discrete sites called replication factories, consisting of DNA polymerases and other replication proteins…”
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Optimal placement of origins for DNA replication
Published in Physical review letters (30-01-2012)“…DNA replication is an essential process in biology and its timing must be robust so that cells can divide properly. Random fluctuations in the formation of…”
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Oxygen-Driven Tumour Growth Model: A Pathology-Relevant Mathematical Approach
Published in PLoS computational biology (01-10-2015)“…Xenografts--as simplified animal models of cancer-differ substantially in vasculature and stromal architecture when compared to clinical tumours. This makes…”
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Signatures of small-world and scale-free properties in large computer programs
Published in Physical review. E, Statistical physics, plasmas, fluids, and related interdisciplinary topics (01-07-2003)“…A large computer program is typically divided into many hundreds or even thousands of smaller units, whose logical connections define a network in a natural…”
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Frontiers of chaotic advection
Published in Reviews of modern physics (14-06-2017)“…This work reviews the present position of and surveys future perspectives in the physics of chaotic advection: the field that emerged three decades ago at the…”
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11
Diffusion in randomly perturbed dissipative dynamics
Published in Europhysics letters (01-11-2014)“…Dynamical systems having many coexisting attractors present interesting properties from both fundamental theoretical and modelling points of view. When such…”
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Strange eigenmodes and chaotic advection in open fluid flows
Published in Europhysics letters (01-05-2014)“…We study the dynamics of mixing of advected fields in open chaotic flows. We propose the eigenfunctions of the stroboscopic advection-diffusion (SAD) operator…”
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13
A Matter of Life or Death: Modeling DNA Damage and Repair in Bacteria
Published in Biophysical journal (16-02-2011)“…DNA damage is a hazard all cells must face, and evolution has created a number of mechanisms to repair damaged bases in the chromosome. Paradoxically, many of…”
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The dynamics of genome replication using deep sequencing
Published in Nucleic acids research (01-01-2014)“…Eukaryotic genomes are replicated from multiple DNA replication origins. We present complementary deep sequencing approaches to measure origin location and…”
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Topology of the conceptual network of language
Published in Physical review. E, Statistical physics, plasmas, fluids, and related interdisciplinary topics (01-06-2002)“…We define two words in a language to be connected if they express similar concepts. The network of connections among the many thousands of words that make up a…”
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High-Resolution Replication Profiles Define the Stochastic Nature of Genome Replication Initiation and Termination
Published in Cell reports (Cambridge) (27-11-2013)“…Eukaryotic genome replication is stochastic, and each cell uses a different cohort of replication origins. We demonstrate that interpreting high-resolution…”
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Inducing chaos by resonant perturbations : Theory and experiment
Published in Physical review letters (03-06-2005)“…We propose a scheme to induce chaos in nonlinear oscillators that either are by themselves incapable of exhibiting chaos or are far away from parameter regions…”
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18
Combinatorial stresses kill pathogenic Candida species
Published in Medical mycology (Oxford) (01-10-2012)“…Pathogenic microbes exist in dynamic niches and have evolved robust adaptive responses to promote survival in their hosts. The major fungal pathogens of…”
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Reacting particles in open chaotic flows
Published in Physical review letters (30-12-2011)“…We study the collision probability p of particles advected by open flows with chaotic advection. We show that p scales with the particle size (or,…”
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Traffic of particles in complex networks
Published in Physical review. E, Statistical, nonlinear, and soft matter physics (01-09-2006)“…The study of the information flow through communication networks, such as the Internet, is of great importance. In the Internet, information flows in discrete…”
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