Search Results - "de Moraes, Manoel"

Overview of the therapeutic potential of piplartine (piperlongumine) by Bezerra, Daniel P., Pessoa, Claudia, de Moraes, Manoel O., Saker-Neto, Nicolau, Silveira, Edilberto R., Costa-Lotufo, Leticia V.

“…Piplartine (piperlongumine, 5,6-dihydro-1-[(2E)-1-oxo-3-(3,4,5-trimethoxyphenyl)-2-propenyl]-2(1H)-pyridinone) is a biologically active alkaloid/amide from…”
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Preoperative Pulmonary Rehabilitation Versus Chest Physical Therapy in Patients Undergoing Lung Cancer Resection: A Pilot Randomized Controlled Trial by Morano, Maria T., PhD, Araújo, Amanda S., PT, Nascimento, Francisco B., PT, da Silva, Guilherme F., PT, Mesquita, Rafael, PT, Pinto, Juliana S., MSc, de Moraes Filho, Manoel O., PhD, Pereira, Eanes D., PhD

“…Abstract Objective To evaluate the effect of 4 weeks of pulmonary rehabilitation (PR) versus chest physical therapy (CPT) on the preoperative functional…”
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2-Methoxyestradiol-3,17- O , O -bis-sulfamate (STX140) Inhibits Proliferation and Invasion via Senescence Pathway Induction in Human BRAFi-Resistant Melanoma Cells by Franco, Ylana Adami, de Moraes, Jr, Manoel Oliveira, Carvalho, Larissa A C, Dohle, Wolfgang, da Silva, Renaira Oliveira, Noma, Isabella Harumi Yonehara, Lima, Keli, Potter, Barry V L, Machado-Neto, João A, Maria-Engler, Silvya Stuchi

“…The endogenous estradiol derivative 2-Methoxyestradiol (2-ME) has shown good and wide anticancer activity but suffers from poor oral bioavailability and…”
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Evaluation of the cytotoxicity of structurally correlated p-menthane derivatives by Andrade, Luciana Nalone, Lima, Tamires Cardoso, Amaral, Ricardo Guimarães, Pessoa, Cláudia do Ó, Filho, Manoel Odorico de Moraes, Soares, Bruno Marques, Nascimento, Lázaro Gomes do, Carvalho, Adriana Andrade, de Sousa, Damião Pergentino

“…Compounds isolated from essential oils play an important role in the prevention and treatment of cancer. Monoterpenes are natural products, and the principal…”
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Evaluation of the antifungal activity in vitro of midazolam against fluconazole-resistant Candida spp. isolates by Holanda, Maria Av, da Silva, Cecília R, de A Neto, João B, do Av Sá, Lívia G, do Nascimento, Francisca Bsa, Barroso, Daiana D, da Silva, Lisandra J, Cândido, Thiago M, Leitão, Amanda C, Barbosa, Amanda D, de Moraes, Manoel O, Cc, Bruno, Júnior, Hélio V Nobre

“…The purpose of this study was to evaluate the antifungal activity of midazolam, alone and in association with azoles, against isolates of clinical spp. in…”
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Synthesis, structural characterization, and cytotoxic evaluation of chalcone derivatives by N. Bandeira, Paulo, L. G. Lemos, Telma, S. Santos, Hélcio, C. S. de Carvalho, Mylena, P. Pinheiro, Daniel, O. de Moraes Filho, Manoel, Pessoa, Cláudia, W. A. Barros-Nepomuceno, Francisco, H. S. Rodrigues, Tigressa, R. V. Ribeiro, Paulo, S. Magalhães, Herbert, M. R. Teixeira, Alexandre

“…Chalcones containing amino or acetamide groups on ring A and electron donating/withdrawing groups on ring B have been shown to have great cytotoxic potential…”
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Synthesis, Characterization and Evaluation of in vitro Antitumor Activities of Novel Chalcone-Quinolinone Hybrid Compounds by d’Oliveira, Giulio, Moura, Andrea, de Moraes, Manoel, Perez, Caridad, Lião, Luciano

“…Chalcone-quinolinone hybrid compounds, as well as the synthesis of such compounds, have few reports in the literature. Such compounds may be quite useful in…”
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Tryptophan catabolites along the indoleamine 2,3-dioxygenase pathway as a biological link between depression and cancer by Barreto, Francisco S, Chaves Filho, Adriano J.M, de Araújo, Márcia C.C.R, de Moraes, Manoel O, de Moraes, Maria E.A, Maes, Michael, de Lucena, David F, Macedo, Danielle S

“…Both depression and cancer are related to a dysregulation of inflammatory and immune pathways. Indeed, depression is associated with increased expression of…”
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In vivo growth-inhibition of Sarcoma 180 tumor by alginates from brown seaweed Sargassum vulgare by de Sousa, Alessandra Paula Alves, Torres, Márcia Rocha, Pessoa, Cláudia, Moraes, Manoel Odorico de, Filho, Francisco Dário Rocha, Alves, Ana Paula Negreiros Nunes, Costa-Lotufo, Letícia Veras

“…Previous studies had demonstrated that alginates from Sargassum sp. (Phaeophyta) showed a considerable activity against various murine tumors. The aim present…”
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Hypomethylation at H19DMR in penile squamous cell carcinoma is not related to HPV infection by da Silva Santos, Renan, Pascoalino Pinheiro, Daniel, Gustavo Hirth, Carlos, Barbosa Bezerra, Maria Júlia, Joyce de Lima Silva-Fernandes, Isabelle, Andréa da Silva Oliveira, Francisca, Viana de Holanda Barros, Maisa, Silveira Ramos, Ester, A Moura, Arlindo, Filho, Odorico de Moraes Manoel, Pessoa, Claudia, Miranda Furtado, Cristiana Libardi

“…Penile squamous cell carcinoma (SCC) is a rare and aggressive tumour mainly related to lifestyle behaviour and human papillomavirus (HPV) infection…”
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The Isoflavanoid (+)‐PTC Regulates Cell‐Cycle Progression and Mitotic Spindle Assembly in a Prostate Cancer Cell Line by Moraes de Farias, Kaio, Rosa‐Ribeiro, Rafaela, Souza, Edmarcia E., Kobarg, Jörg, Banwell, Martin G., Brito Vieira Neto, José, Leyenne Alves Sales, Sarah, Roberto Ribeiro Costa, Paulo, Cavalcante dos Santos, Rafael, Vilaça Gaspar, Francisco, Gomes Barreto Junior, Amaro, Conceição Ferreira Oliveira, Maria, Odorico de Moraes, Manoel, Libardi M. Furtado, Cristiana, Carvalho, Hernandes F., Pessoa, Claudia

“…Prostate cancer is the second most common malignancy in men and the development of effective therapeutic strategies remains challenging when more advanced,…”
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Synthesis and cytotoxicity screening of substituted isobenzofuranones designed from anacardic acids by Logrado, Lúcio P.L., Santos, Camila O., Romeiro, Luiz A.S., Costa, Arinice M., Ferreira, José R.O., Cavalcanti, Bruno C., Manoel de Moraes, O., Costa-Lotufo, Letícia V., Pessoa, Cláudia, dos Santos, Maria L.

“…This work is part of a large program, which seeks to discover new antitumor isobenfuranones designed from anacardic acids. The synthetic strategy for the…”
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Ursodeoxycholic acid in the prevention of gallstones in patients subjected to Roux-en-Y gastric bypass by Machado, Francisco Heine Ferreira, Castro Filho, Heladio Feitosa de, Babadopulos, Rodrigo Feitosa de Albuquerque Lima, Rocha, Hermano Alexandre Lima, Costa, Maria da Conceição Cavalcante, Rocha, José Lima de Carvalho, Moraes Filho, Manoel Odorico de

“…Abstract Purpose: To evaluate the contribution of ursodeoxycholic acid (UDCA) in the first 12 months after Roux-en-Y gastric bypass in the prevention of…”
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Peroxiredoxin-2 represses NRAS-mutated melanoma cells invasion by modulating EMT markers by Noma, Isabella Harumi Yonehara, Carvalho, Larissa Anastacio da Costa, Camarena, Denisse Esther Mallaupoma, Silva, Renaira Oliveira, Moraes Junior, Manoel Oliveira de, de Souza, Sophia Tavares, Newton-Bishop, Julia, Nsengimana, Jérémie, Maria-Engler, Silvya Stuchi

“…The second most common mutation in melanoma occurs in NRAS oncogene, being a more aggressive disease that has no effective approved treatment. Besides,…”
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Brazoides A-D, New Alkaloids from Justicia gendarussa Burm. F. Species by Souza, Luciana, Almeida, Macia, Lemos, Telma, Ribeiro, Paulo, Canuto, Kirley, Braz-Filho, Raimundo, Del Cistia, Catarina, Sant’Anna, Carlos Mauricio, Barreto, Francisco, de Moraes, Manoel

“…Four new alkaloids, Brazoides A-D, together with three known compounds squalene, β-sitosterol and lupeol, were isolated from leaves of Justicia gendarussa…”
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Antitumor properties of a sulfated polysaccharide from the red seaweed Champia feldmannii (Diaz-Pifferer) by Lins, Kézia O. A. L., Bezerra, Daniel P., Alves, Ana Paula N. N., Alencar, Nylane M. N., Lima, Michael W., Torres, Valeska M., Farias, Wladimir R. L., Pessoa, Cláudia, de Moraes, Manoel O., Costa-Lotufo, Letícia V.

“…In recent years, much attention has been focused on polysaccharides isolated from natural sources. The aim of this study was to investigate the in vitro and in…”
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Occupational and life-style factors-acquired mutagenicity in agric-workers of northeastern Brazil by Chaves, Tatiana Vieira Souza, Islam, Muhammad Torequl, de Moraes, Manoel Odoríco, de Alencar, Marcus Vinícius Oliveira Barros, Gomes, Débora Cássia Vieira, de Carvalho, Rodrigo Mendes, Maluf, Sharbel Weider, de Moura do Amaral, Fabrício Pires, Paz, Márcia Fernanda Correia Jardim, Cerqueira, Gilberto Santos, Rolim, Hercília Maria Lins, de Castro e Sousa, João Marcelo, de Carvalho Melo-Cavalcante, Ana Amélia, de Moraes, Maria Elisabete Amaral

“…Pesticides are a complex mixture of chemicals used to protect crops from a number of pests and diseases. They have been considered as potential mutagenic…”
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Next‐generation of melanoma researchers: Trainee perspectives from around the world by Webster, Marie R., Brathwaite, Roderick, Narula, Jeremy A. Bravo, Elad, Vissy M., Ma, Yanni, Ng, Mei Fong, Moraes Junior, Manoel Oliveira, Shabangu, Majahonkhe, Tsiavou, Christina, Villanueva, Jessie, Rebecca, Vito W.

“…The Society for Melanoma Research (SMR) was created 20 years ago and has unequivocally contributed to the vast progress of the field, particularly for the…”
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Synthesis and Evaluation of Cytotoxic Effects of Amino-ester Derivatives of Natural α,β-Amyrin Mixture by Victor, Mauricio, David, Jorge, dos Santos, Marcelo, Barreiros, André, Barreiros, Marizeth, Andrade, Fernanda, Carvalho, Adriana, Luciano, Maria, de Moraes, Manoel, Barros-Nepomuceno, Francisco, Pessoa, Claudia

“…Natural α,β-amyrins were isolated from endemic Brazilian Esenbeckia grandiflora Mart., and eight synthetic derivatives were obtained by esterification…”
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Novel Ruthenium‐based Nitrosyl Complexes: NO Donation and Vasorelaxant Potentials for Cardiovascular Therapeutics by Gouveia Júnior, Florêncio S., Sousa, Allandeiverson S., Silva, Renally B., Rocha, Danilo G., Teixeira, Edson H., Odorico de Moraes Filho, Manoel, Jamacaru, Francisco Vagnaldo F., Serra Azul Monteiro, Helena, Jorge, Roberta Jeane B., Wink, David A., Sousa, Eduardo Henrique S., F. Lopes, Luiz Gonzaga

“…Nitrosyl ruthenium complexes have emerged as promising platforms for the controlled delivery of nitric oxide (NO) and nitroxyl (HNO), both of which possess…”
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