Search Results - "de Montis, Maria Graziella"

Targeting PPARα in the rat valproic acid model of autism: focus on social motivational impairment and sex-related differences by Scheggi, Simona, Guzzi, Francesca, Braccagni, Giulia, De Montis, Maria Graziella, Parenti, Marco, Gambarana, Carla

“…Abstract Background The social motivational theory of autism spectrum disorder (ASD) focuses on social anhedonia as key causal feature of the impaired peer…”
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5alpha-reductase inhibitors dampen L-DOPA-induced dyskinesia via normalization of dopamine D1-receptor signaling pathway and D1-D3 receptor interaction by Fanni, Silvia, Scheggi, Simona, Rossi, Francesca, Tronci, Elisabetta, Traccis, Francesco, Stancampiano, Roberto, De Montis, Maria Graziella, Devoto, Paola, Gambarana, Carla, Bortolato, Marco, Frau, Roberto, Carta, Manolo

“…Although 1-3,4-dihydroxyphenylalanine (L-DOPA) is the mainstay therapy for treating Parkinson's disease (PD), its long-term administration is accompanied by…”
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PPARα Signaling: A Candidate Target in Psychiatric Disorder Management by Scheggi, Simona, Pinna, Graziano, Braccagni, Giulia, De Montis, Maria Graziella, Gambarana, Carla

“…Peroxisome proliferator-activator receptors (PPARs) regulate lipid and glucose metabolism, control inflammatory processes, and modulate several brain…”
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Behavioral expression of cocaine sensitization in rats is accompanied by a distinct pattern of modifications in the PKA/DARPP-32 signaling pathway by Scheggi, Simona, Raone, Anna, De Montis, Maria Graziella, Tagliamonte, Alessandro, Gambarana, Carla

“…Repeated cocaine administration induces behavioral sensitization and modifications in the phosphorylation pattern of dopamine and cAMP-regulated phosphoprotein…”
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PPAR-alpha agonists as novel antiepileptic drugs: preclinical findings by Puligheddu, Monica, Pillolla, Giuliano, Melis, Miriam, Lecca, Salvatore, Marrosu, Francesco, De Montis, Maria Graziella, Scheggi, Simona, Carta, Gianfranca, Murru, Elisabetta, Aroni, Sonia, Muntoni, Anna Lisa, Pistis, Marco

“…Nicotinic acetylcholine receptors (nAChRs) are involved in seizure mechanisms. Hence, nocturnal frontal lobe epilepsy was the first idiopathic epilepsy linked…”
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Anti-anhedonic activity of long-term lithium treatment in rats exposed to repeated unavoidable stress by Marchese, Giovanna, Scheggi, Simona, Secci, Maria Elena, De Montis, Maria Graziella, Gambarana, Carla

“…Behavioural and neurochemical responses to palatable food exposure represent an index of hedonic competence. In rats, a palatable meal increases extra-neuronal…”
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Synthetic Peptides in the Form of Dendrimers Become Resistant to Protease Activity by Bracci, Luisa, Falciani, Chiara, Lelli, Barbara, Lozzi, Luisa, Runci, Ylenia, Pini, Alessandro, De Montis, Maria Graziella, Tagliamonte, Alessandro, Neri, Paolo

“…In previous papers, we observed that dendrimers of peptide mimotopes of the nicotinic receptor ligand site are strong antidotes against the lethality of the…”
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Antidepressant and pro-motivational effects of repeated lamotrigine treatment in a rat model of depressive symptoms by Scheggi, Simona, Pelliccia, Teresa, Cuomo, Alessandro, De Montis, Maria Graziella, Gambarana, Carla

“…The antiepileptic lamotrigine is approved for maintenance treatment of bipolar disorder and augmentation therapy in treatment-resistant depression. Previous…”
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Making Sense of Rodent Models of Anhedonia by Scheggi, Simona, De Montis, Maria Graziella, Gambarana, Carla

“…A markedly reduced interest or pleasure in activities previously considered pleasurable is a main symptom in mood disorder and psychosis and is often present…”
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A Chronic Stress that Impairs Reactivity in Rats Also Decreases Dopaminergic Transmission in the Nucleus Accumbens: A Microdialysis Study by Gambarana, Carla, Masi, Flavio, Tagliamonte, Alessandro, Scheggi, Simona, Ghiglieri, Ombretta, Graziella De Montis, Maria

“…: Chronic stress induces in rats a decreased reactivity toward noxious stimuli (escape deficit), which can be reverted by antidepressant treatments. The…”
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F2-isoprostane receptors on hepatic stellate cells by Gardi, Concetta, Arezzini, Beatrice, Monaco, Barbara, De Montis, Maria Graziella, Vecchio, Daniela, Comporti, Mario

“…F 2 -isoprostanes are considered as the most reliable markers of oxidative stress and can be used to evaluate the oxidative status in a number of human…”
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DARPP‐32 in the orchestration of responses to positive natural stimuli by Scheggi, Simona, De Montis, Maria Graziella, Gambarana, Carla

“…Dopamine‐ and cAMP‐regulated phosphoprotein (Mr 32 kDa, DARPP‐32) is an integrator of multiple neuronal signals and plays a crucial role particularly in…”
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Aripiprazole relieves motivational anhedonia in rats by Scheggi, Simona, Pelliccia, Teresa, Gambarana, Carla, De Montis, Maria Graziella

“…Anhedonia is considered a relevant feature in depression and psychosis, characterized by poor treatment outcome, and associated with deficits in mesolimbic…”
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Heightened reward response is associated with HCN2 overexpression in the ventral tegmental area in morphine-sensitized rats by Scheggi, Simona, Braccagni, Giulia, De Montis, Maria Graziella, Gambarana, Carla

“…Morphine sensitization is associated with increased locomotion and stereotypies in rats. This persistent condition has been proposed as a model of manic-like…”
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PPARα modulation of mesolimbic dopamine transmission rescues depression-related behaviors by Scheggi, Simona, Melis, Miriam, De Felice, Marta, Aroni, Sonia, Muntoni, Anna Lisa, Pelliccia, Teresa, Gambarana, Carla, De Montis, Maria Graziella, Pistis, Marco

“…Depressive disorders cause a substantial burden for the individual and the society. Key depressive symptoms can be modeled in animals and enable the…”
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Fasting biases μ -opioid receptors toward β –arrestin2 dependent signaling in the accumbens shell by Scheggi, Simona, Ferrari, Alberto, Pelliccia, Teresa, Devoto, Paola, De Montis, Maria Graziella, Gambarana, Carla

“…Highlights • Acute morphine administration increases motility only in food-deprived rats and this is a β-arrestin2-dependent effect. • Acute morphine increases…”
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Targeting PPAR[alpha] in the rat valproic acid model of autism: focus on social motivational impairment and sex-related differences by Scheggi, Simona, Guzzi, Francesca, Braccagni, Giulia, De Montis, Maria Graziella, Parenti, Marco, Gambarana, Carla

“…Background The social motivational theory of autism spectrum disorder (ASD) focuses on social anhedonia as key causal feature of the impaired peer…”
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NMDA receptors play an anti-aggregating role in human platelets by Franconi, F, Miceli, M, De Montis, M G, Crisafi, E L, Bennardini, F, Tagliamonte, A

“…Receptors for different monoamines, peptides and other neurohormones are present in the plasma membrane of platelets, and the sophisticated process of…”
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Modifications in DARPP-32 phosphorylation pattern after repeated palatable food consumption undergo rapid habituation in the nucleus accumbens shell of non-food-deprived rats by Danielli, Barbara, Scheggi, Simona, Grappi, Silvia, Marchese, Giovanna, De Montis, Maria Graziella, Tagliamonte, Alessandro, Gambarana, Carla

“…In non-food-deprived rats a palatable meal induces a transient increase in dopamine output in the prefrontal cortex and nucleus accumbens shell and core;…”
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Dopamine output in the nucleus accumbens shell is related to the acquisition and the retention of a motivated appetitive behavior in rats by Masi, Flavio, Scheggi, Simona, Mangiavacchi, Simona, Tolu, Pierluigi, Tagliamonte, Alessandro, Graziella De Montis, Maria, Gambarana, Carla

“…Chronic stress exposure consistently impairs the reactivity to aversive and pleasurable stimuli in rats; these behavioral modifications are associated with a…”
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