Search Results - "de Miguel, María P"
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Regenerative Surgery of the Corneal Stroma for Advanced Keratoconus: 1-Year Outcomes
Published in American journal of ophthalmology (01-07-2019)“…This study evaluated 1-year safety and efficacy outcomes of corneal stroma cell therapy. Therapy consisted of implanting autologous adipose-derived adult stem…”
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Corneal Stromal Regeneration Therapy for Advanced Keratoconus: Long-term Outcomes at 3 Years
Published in Cornea (01-06-2021)“…To report the 3-year clinical outcomes of corneal stromal cell therapy consisting of the intrastromal implantation with autologous adipose-derived adult stem…”
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3
Autoantibodies Against Perilipin 1 as a Cause of Acquired Generalized Lipodystrophy
Published in Frontiers in immunology (19-09-2018)“…Acquired generalized lipodystrophy (AGL) is a rare condition characterized by an altered distribution of adipose tissue and predisposition to develop hepatic…”
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In vivo confocal microscopy evaluation of infiltrated immune cells in corneal stroma treated with cell therapy in advanced keratoconus
Published in Journal of ophthalmic inflammation and infection (26-01-2024)“…Purpose This study investigates immune cell (ICs) infiltration in advanced keratoconus patients undergoing autologous adipose-derived adult stem cell (ADASC)…”
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Corneal Regeneration Using Adipose-Derived Mesenchymal Stem Cells
Published in Cells (Basel, Switzerland) (01-08-2022)“…Adipose-derived stem cells are a subtype of mesenchymal stem cell that offers the important advantage of being easily obtained (in an autologous manner) from…”
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Evidence of ongoing complement activation on adipose tissue from an 11‐year‐old girl with Barraquer–Simons syndrome
Published in Journal of dermatology (01-12-2020)“…Barraquer–Simons syndrome (BSS), a form of acquired partial lipodystrophy, is a rare condition characterized by gradual loss of adipose tissue from the upper…”
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Corneal Stroma Enhancement With Decellularized Stromal Laminas With or Without Stem Cell Recellularization for Advanced Keratoconus
Published in American journal of ophthalmology (01-02-2018)“…This phase 1 study seeks to preliminarily evaluate the safety and efficacy of decellularized human corneal stromal lamina transplantation with or without…”
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Iodotyrosines Are Biomarkers for Preclinical Stages of Iodine-Deficient Hypothyroidism in Dehal1 -Knockout Mice
Published in Thyroid (New York, N.Y.) (01-06-2023)“…Iodine is required for the synthesis of thyroid hormone (TH), but its natural availability is limited. Dehalogenase1 (Dehal1) recycles iodine from mono- and…”
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Priming human adipose‐derived mesenchymal stem cells for corneal surface regeneration
Published in Journal of cellular and molecular medicine (01-06-2021)“…Limbal stem cells (LSC) maintain the transparency of the corneal epithelium. Chemical burns lead the loss of LSC inducing an up‐regulation of pro‐inflammatory…”
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The syndrome of central hypothyroidism and macroorchidism: IGSF1 controls TRHR and FSHB expression by differential modulation of pituitary TGFβ and Activin pathways
Published in Scientific reports (06-03-2017)“…IGSF1 (Immunoglobulin Superfamily 1) gene defects cause central hypothyroidism and macroorchidism. However, the pathogenic mechanisms of the disease remain…”
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Adipose-derived mesenchymal stem cells slow disease progression of acute-on-chronic liver failure
Published in Biomedicine & pharmacotherapy (01-07-2017)“…Graphical abstract…”
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Derivation of Limbal Stem Cells from Human Adult Mesenchymal Stem Cells for the Treatment of Limbal Stem Cell Deficiency
Published in International journal of molecular sciences (25-01-2023)“…Approximately 10 million individuals have blindness due to limbal stem cell (LSCs) deficiency, one of the most challenging problems in ophthalmology. To…”
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Corneal Stroma Regeneration: New Approach for the Treatment of Cornea Disease
Published in Asia-Pacific journal of ophthalmology (Philadelphia, Pa.) (01-11-2020)“…Corneal grafting is one of the most common forms of human tissue transplantation. The corneal stroma is responsible for many characteristics of the cornea. For…”
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Cdc25b phosphatase is required for resumption of meiosis during oocyte maturation
Published in Nature genetics (01-04-2002)“…In a wide variety of animal species, oocyte maturation is arrested temporarily at prophase of meiosis I (ref. 1). Resumption of meiosis requires activation of…”
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Pluripotent Stem Cells: Origin, Maintenance and Induction
Published in Stem cell reviews (01-12-2010)“…Pluripotency is defined as the potential of a cell to differentiate into cells of the three germ layers: endoderm, mesoderm and ectoderm. In vivo, the presence…”
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Cellular Therapy With Human Autologous Adipose-Derived Adult Stem Cells for Advanced Keratoconus
Published in Cornea (01-08-2017)“…The aim of this phase 1 study was to preliminarily evaluate the safety and efficacy of autologous adipose-derived adult stem cell (ADASC) implantation within…”
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Corneal Stromal Regeneration Therapy for Advanced Keratoconus: Long-term Outcomes at 3 Years
Published in Cornea (01-06-2021)Get full text
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Corneal Stroma Cell Density Evolution in Keratoconus Corneas Following the Implantation of Adipose Mesenchymal Stem Cells and Corneal Laminas: An In Vivo Confocal Microscopy Study
Published in Investigative ophthalmology & visual science (17-04-2020)“…To report the corneal stroma cell density evolution identified by in vivo corneal confocal microscopy in humans using injected autologous adipose-derived adult…”
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Corneal stroma regeneration: Preclinical studies
Published in Experimental eye research (01-01-2021)“…Corneal grafting is one of the most common and successful forms of human tissue transplantation in the world, but the need for corneal grafting is growing and…”
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Cornea and ocular surface treatment
Published in Current stem cell research & therapy (01-06-2010)“…In addition to being a protective shield, the cornea represents two thirds of the eye's refractive power. Corneal pathology can affect one or all of the…”
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