Search Results - "de Mendonça Aquino, Thiago"

Computer-Aided Design, Synthesis, and Antiviral Evaluation of Novel Acrylamides as Potential Inhibitors of E3-E2-E1 Glycoproteins Complex from Chikungunya Virus by Passos, Gabriel Felipe Silva, Gomes, Matheus Gabriel Moura, Aquino, Thiago Mendonça de, Araújo-Júnior, João Xavier de, Souza, Stephannie Janaina Maia de, Cavalcante, João Pedro Monteiro, Santos, Elane Conceição Dos, Bassi, Ênio José, Silva-Júnior, Edeildo Ferreira da

“…Chikungunya virus (CHIKV) causes an infectious disease characterized by inflammation and pain of the musculoskeletal tissues accompanied by swelling in the…”
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Cruzain and Rhodesain Inhibitors: Last Decade of Advances in Seeking for New Compounds Against American and African Trypanosomiases by Dos Santos Nascimento, Igor José, de Aquino, Thiago Mendonça, da Silva-Júnior, Edeildo Ferreira

“…Neglected tropical diseases (NTDs) are a group of approximately 20 diseases that affect part of the population in Sub- and Tropical countries. In the past,…”
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Natural Compounds as Inhibitors of Aβ Peptide and Tau Aggregation by Monteiro, Kadja Luana Chagas, de Aquino, Thiago Mendonça, da Silva-Júnior, Edeildo Ferreira

“…Neurodegenerative conditions like Alzheimer's disease (AD), Parkinson's disease (PD), and amyotrophic lateral sclerosis (ALS) encompass disorders characterized…”
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An Update on Staphylococcus aureus NorA Efflux Pump Inhibitors by Monteiro, Kadja Luana Chagas, de Aquino, Thiago Mendonça, Mendonça Junior, Francisco Jaime B

“…Methicillin-resistant and vancomycin-resistant Staphylococcus aureus are pathogens causing severe infectious diseases that pose real public health threats…”
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Molecular Modeling Targeting Transmembrane Serine Protease 2 (TMPRSS2) as an Alternative Drug Target Against Coronaviruses by Dos Santos Nascimento, Igor José, da Silva-Júnior, Edeildo Ferreira, de Aquino, Thiago Mendonça

“…Since December 2019, the new Coronavirus disease (COVID-19) caused by the etiological agent SARS-CoV-2 has been responsible for several cases worldwide,…”
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The rating of perceived exertion is able to differentiate the post-matches metabolomic profile of elite U-20 soccer players by Marinho, Alisson Henrique, Sousa, Filipe Antonio de Barros, Vilela, Rubens de Alcântara Moura Pimentel, Balikian, Pedro, de Souza Bento, Edson, de Mendonça Aquino, Thiago, Crispim, Alessandre, Ataide-Silva, Thays, de Araujo, Gustavo Gomes

“…Purpose The study aimed to assess the metabolic impact of elite Brazilian U-20 players using the rating of perceived exertion scale (RPE) to discriminate…”
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Insights on Natural Products Against Amyotrophic Lateral Sclerosis (ALS) by Monteiro, Kadja Luana Chagas, Dos Santos Alcântara, Marcone Gomes, de Aquino, Thiago Mendonça, da Silva-Júnior, Edeildo Ferreira

“…Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease that causes the death of motor neurons and consequent muscle paralysis. Despite…”
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Active Essential Oils and Their Components in Use against Neglected Diseases and Arboviruses by Ribeiro, Frederico Fávaro, Mendonça Junior, F. J. B., de Aquino, Thiago Mendonça, Araújo, Rodrigo Santos Aquino de, de Moura, Ricardo Olímpio, Scotti, Marcus Tullius, Monteiro, Alex France M., Scotti, Luciana, Luna, Isadora Silva, Luna, Emanuela Coutinho, Monteiro, Kadja Luana Chagas

“…The term neglected diseases refers to a group of infections caused by various classes of pathogens, including protozoa, viruses, bacteria, and helminths, most…”
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Potentiating‐antibiotic activity and absorption, distribution, metabolism, excretion and toxicity properties (ADMET) analysis of synthetic thiadiazines against multi‐drug resistant (MDR) strains by Araújo, Ana Carolina Justino, Freitas, Priscilla Ramos, Araújo, Isaac Moura, Siqueira, Gustavo Miguel, Oliveira Borges, João Arthur, Alves, Daniel Sampaio, Miranda, Gustavo Marinho, Santos Nascimento, Igor José, Araújo‐Júnior, João Xavier, Silva‐Júnior, Edeildo Ferreira, Aquino, Thiago Mendonça, Junior, Francisco Jaime Bezerra Mendonça, Marinho, Emmanuel Silva, Santos, Helcio Silva, Tintino, Saulo Relison, Coutinho, Henrique Douglas Melo

“…Background Thiadiazines are heterocyclic compounds that contain two nitrogen atoms and one sulfur atom in their structure. These synthetic molecules have…”
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Medicinal Chemistry of Inhibitors Targeting Resistant Bacteria by Monteiro, Kadja Luana Chagas, Silva, Osmar Nascimento, Dos Santos Nascimento, Igor José, Mendonça Júnior, Francisco Jaime Bezerra, Aquino, Pedro Gregório Vieira, da Silva-Júnior, Edeildo Ferreira, de Aquino, Thiago Mendonça

“…The discovery of antibiotics was a revolutionary feat that provided countless health benefits. The identification of penicillin by Alexander Fleming initiated…”
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Synthesis, anticancer activities and experimental-theoretical DNA interaction studies of 2-amino-4-phenyl-4H-benzo[h]chromene-3-carbonitrile by Braga, Taniris Cafiero, Silva, Marina Magalhães, Nascimento, Eduarda O.O., Dantas da Silva, Edjan Carlos, de Freitas Rego, Yuri, Mandal, Mullicka, Alves de Souza, Zaqueu, Tasca Góis Ruiz, Ana Lúcia, Ernesto de Carvalho, João, Martins, Felipe Terra, Figueiredo, Isis Martins, Mendonça de Aquino, Thiago, Moreira da Silva, Cleiton, Mandal, Bhagirath, Brahmachari, Goutam, Caldas Santos, Josué Carinhanha, de Fátima, Ângelo

“…Twenty chromenes were synthesized with good to excellent yields (70–96%). From the series of chromenes herein tested, compounds 14, 12, 15, 16, 17, 18, and 20…”
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The new psychoactive substances 25H-NBOMe and 25H-NBOH induce abnormal development in the zebrafish embryo and interact in the DNA major groove by de Barros, Wellington Alves, Nunes, Camila da Silva, Souza, Juliana Alves da Costa Ribeiro, Nascimento, Igor José dos Santos, Figueiredo, Isis Martins, de Aquino, Thiago Mendonça, Vieira, Leonardo, Farias, Davi, Santos, Josué Carinhanha Caldas, de Fátima, Ângelo

“…[Display omitted] •25H-NBOMe and 25H-NBOH recreational drugs induces abnormal formation in zebrafish embryos.•Biophysical and theoretical studies indicate that…”
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Cannabinoid pharmacology and its therapeutic uses in Alzheimer's disease by Monteiro, Kadja, dos Santos Alcântara, Marcone, de Aquino, Thiago, da Silva-Júnior, Edeildo

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Development and Validation of HPLC-DAD and UHPLC-DAD Methods for the Simultaneous Determination of Guanylhydrazone Derivatives Employing a Factorial Design by Azevedo de Brito, Wanessa, Gomes Dantas, Monique, Andrade Nogueira, Fernando Henrique, Ferreira da Silva-Júnior, Edeildo, Xavier de Araújo-Júnior, João, Aquino, Thiago Mendonça de, Adélia Nogueira Ribeiro, Êurica, da Silva Solon, Lilian Grace, Soares Aragão, Cícero Flávio, Barreto Gomes, Ana Paula

“…Guanylhydrazones are molecules with great pharmacological potential in various therapeutic areas, including antitumoral activity. Factorial design is an…”
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Evaluation of the interaction of a guanylhydrazone derivative with cobalt ferrite nanoparticles and PAMAM electrochemical and UV/visible spectroscopic techniques by da Silva, Marílya Palmeira Galdino, Candido, Anna Caroline Lima, de Araújo-Júnior, João Xavier, Silva, Anielle Christine Almeida, Dantas, Noelio Oliveira, de Aquino, Thiago Mendonça, de Abreu, Fabiane Caxico

“…Nowadays, scientific research grows a lot around nanotechnology, which connects many areas of knowledge such as electrochemistry and magnetic nanoparticles…”
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Insights on Dengue and Zika NS5 RNA-dependent RNA polymerase (RdRp) inhibitors by Nascimento, Igor José dos Santos, Santos-Júnior, Paulo Fernando da Silva, Aquino, Thiago Mendonça de, Araújo-Júnior, João Xavier de, Silva-Júnior, Edeildo Ferreira da

“…Over recent years, many outbreaks caused by (re)emerging RNA viruses have been reported worldwide, including life-threatening Flaviviruses, such as Dengue…”
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Biophysical studies of human serum albumin with cocaine and cocaethylene: Understanding the drug-protein interaction in simulated physiological conditions by Maciel, Thamilla Maria Silva, José dos Santos Nascimento, Igor, da Silva Neto, Leonardo, da Silva Maia, Angélica Faleiros, Figueiredo, Isis Martins, de Aquino, Thiago Mendonça, de Fátima, Ângelo, Santos, Josué Carinhanha Caldas

“…[Display omitted] •Simulations of cocaine and cocaethylene interactions with HSA were conducted.•Cocaethylene lasts longer in the body due to a higher HSA…”
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Metabolomic profiling of elite female soccer players: urinary biomarkers over a championship season by Gouveia, Maria Mariana Sabino, do Nascimento, Maria Beatriz Augusto, Crispim, Alessandre Carmo, da Rocha, Edmilson Rodrigues, dos Santos, Maryssa Pontes Pinto, Bento, Edson de Souza, De Aquino, Thiago Mendonça, Balikian, Pedro, Rodrigues, Natália Almeida, Ataide-Silva, Thays, de Araujo, Gustavo Gomes, Sousa, Filipe Antonio de Barros

“…Introduction In soccer, most studies evaluate metabolic profile changes in male athletes, often using data from a single match. Given the current landscape of…”
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Coumarin Derivatives Exert Anti-Lung Cancer Activity by Inhibition of Epithelial-Mesenchymal Transition and Migration in A549 Cells by de Araújo, Rodrigo Santos Aquino, Carmo, Julianderson de Oliveira Dos Santos, de Omena Silva, Simone Lara, Costa da Silva, Camila Radelley Azevedo, Souza, Tayhana Priscila Medeiros, Mélo, Natália Barbosa de, Bourguignon, Jean-Jacques, Schmitt, Martine, Aquino, Thiago Mendonça de, Rodarte, Renato Santos, Moura, Ricardo Olímpio de, Barbosa Filho, José Maria, Barreto, Emiliano, Mendonça-Junior, Francisco Jaime Bezerra

“…A series of coumarin derivatives and isosteres were synthesized from the reaction of triflic intermediates with phenylboronic acids, terminal alkynes, and…”
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Molecular Docking Studies Applied to a Dataset of Cruzain Inhibitors by da Silva-Junior, Edeildo Ferreira, Barcellos Franca, Paulo Henrique, Ribeiro, Frederico Favaro, Bezerra Mendonca-Junior, Francisco Jaime, Scotti, Luciana, Scotti, Marcus Tullius, de Aquino, Thiago Mendonca, de Araujo-Junior, Joao Xavier

“…Chagas' disease is one of the main causes of heart failure in developing countries. The disadvantages of current therapy include the undesirable side-effects,…”
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