Search Results - "de Melo Medeiros, Millena"

New phosphodiesterase-4 inhibitors present airways relaxant activity in a guinea pig acute asthma model by Martins, Italo Rossi Roseno, de Melo Medeiros, Millena, Vasconcelos, Luiz Henrique César, Silva, Maria da Conceição Correia, Queiroga, Fernando Ramos, Cavalcante-Silva, Luiz Henrique Agra, da Costa Nunes, Isabelle Karine, Lima, Lidia Moreira, da Silva, Patricia Mirella, Silva, Bagnólia Araújo da

“…Asthma is a disease characterized by chronic inflammation and hyper responsiveness of airways. We aimed to assess the relaxant potential of phosphodiesterase-4…”
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Discovery of sulfonyl hydrazone derivative as a new selective PDE4A and PDE4D inhibitor by lead-optimization approach on the prototype LASSBio-448: In vitro and in vivo preclinical studies by Nunes, Isabelle Karine da Costa, de Souza, Everton Tenório, Martins, Italo Rossi Roseno, Barbosa, Gisele, Moraes Junior, Manoel Oliveira de, Medeiros, Millena de Melo, Silva, Sheyla Welma Duarte, Balliano, Tatiane Luciano, da Silva, Bagnólia Araújo, Silva, Patrícia Machado Rodrigues, Carvalho, Vinicius de Frias, Martins, Marco Aurélio, Lima, Lidia Moreira

“…Phosphodiesterase 4 (PDE4) inhibitors have emerged as a new strategy to treat asthma and other lung inflammatory diseases. Searching for new PDE4 inhibitors,…”
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