Search Results - "de Mattos Oliveira, Larissa"
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Compounds from Natural Products Candidates to Drug for Chikungunya Virus Infection: A Systematic Review
Published in Current drug targets (01-01-2024)“…Chikungunya fever is a disease caused by infection with the Chikungunya virus, transmitted by Aedes aegypti and Aedes albopictus mosquitoes. Despite its…”
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Superoxide Dismutase Inhibitors against Malaria, Leishmaniasis, and Chagas Disease: Systematic Review
Published in Current drug targets (01-01-2023)“…Diseases caused by protozoa are one of the leading causes of death worldwide, especially in tropical regions such as Brazil. Chagas disease, leishmaniasis, and…”
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The flavonoid agathisflavone modulates the microglial neuroinflammatory response and enhances remyelination
Published in Pharmacological research (01-09-2020)“…[Display omitted] •Agathisflavone enhances remyelination through modulating neuroinflammation.•Agathisflavone induces a polarization in microglia from an M1 to…”
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Identification of novel antiplasmodial compound by hierarquical virtual screening and in vitro assays
Published in Journal of biomolecular structure & dynamics (13-06-2021)“…Malaria is an infectious disease caused by protozoa of the genus Plasmodium spp. with approximately 219 million cases in 2017. P. falciparum is main…”
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Virtual screening to identify Leishmania braziliensis N-myristoyltransferase inhibitors: pharmacophore models, docking, and molecular dynamics
Published in Journal of molecular modeling (01-09-2018)“…Leishmaniasis is caused by several protozoa species belonging to genus Leishmania that are hosted by humans and other mammals. Millions of new cases are…”
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Alkene lactones from Persea fulva (Lauraceae): Evaluation of their effects on tumor cell growth in vitro and molecular docking studies
Published in Bioorganic chemistry (01-05-2019)“…[Display omitted] •Four alkene lactones were isolated from Persea fulva, including a new majoranolide B (1).•Isolates showed antitumoral activity in rat C6…”
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Identification of new promising Plasmodium falciparum superoxide dismutase allosteric inhibitors through hierarchical pharmacophore-based virtual screening and molecular dynamics
Published in Journal of molecular modeling (01-08-2018)“…Malaria is the world’s most widespread protozoan infection, being responsible for more than 445,000 annual deaths. Among the malaria parasites, Plasmodium…”
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Pharmacophore modeling, docking and molecular dynamics to identify Leishmania major farnesyl pyrophosphate synthase inhibitors
Published in Journal of molecular modeling (01-11-2018)“…Leishmaniasis is caused by protozoa of the genus Leishmania spp. and is considered the second most important protozoa in the world due to the number of cases…”
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A novel antiplasmodial compound: integration of in silico and in vitro assays
Published in Journal of biomolecular structure & dynamics (22-09-2022)“…Malaria is a disease caused by Plasmodium genus. which P. falciparum is responsible for the most severe form of the disease, cerebral malaria. In 2018, 405,000…”
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In Vitro and In Silico Evaluation of the Leishmanicidal and Trypanocidal Activities of Lignan Methylpiperitol Isolated from Persea Fulva
Published in Chemistry & biodiversity (01-08-2024)“…Neglected Tropical Diseases are a significant concern as they encompass various infections caused by pathogens prevalent in tropical regions. The limited and…”
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