Search Results - "de Mattos, Marcos Carlos"
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Recent Advances in Lipase-Mediated Preparation of Pharmaceuticals and Their Intermediates
Published in International journal of molecular sciences (11-12-2015)“…Biocatalysis offers an alternative approach to conventional chemical processes for the production of single-isomer chiral drugs. Lipases are one of the most…”
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Kinetic resolution of drug intermediates catalyzed by lipase B from Candida antarctica immobilized on immobead‐350
Published in Biotechnology progress (01-07-2018)“…Novozyme 435, which is a commercial immobilized lipase B from Candida antarctica (CALB), has been proven to be inadequate for the kinetic resolution of…”
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Taguchi design-assisted co-immobilization of lipase A and B from Candida antarctica onto chitosan: Characterization, kinetic resolution application, and docking studies
Published in Chemical engineering research & design (01-01-2022)“…[Display omitted] •Taguchi design-assisted Co-immobilization of Lipase.•Co-immobilization of Lipase A and B from Candida antarctica onto Chitosan…”
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Quantification of Barbatusin and 3β-Hydroxy-3-deoxybarbatusin in Plectranthus Species by HPLC-DAD
Published in International Journal of Analytical Chemistry (01-01-2017)“…The concentration of diterpenes barbatusin (1) and 3β-hydroxy-3-deoxybarbatusin (2) in the extracts from leaves of Plectranthus grandis, P. barbatus, P…”
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Optimization and theoretical analysis of lipase-catalyzed enzymatic esterification of glycerol for efficient glycerides synthesis
Published in Biochemical engineering journal (01-09-2023)“…Eversa® Transform 2.0 is a lipase derived from Thermomyces lanuginosus produced by a genetically modified microorganism. It has a low production cost, high…”
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Semisynthesis and Cytotoxic Activities of Novel Oxime Ester Derivatives of the Diterpene Stemodin
Published in Journal of the Brazilian Chemical Society (2024)“…Stemodin (1) is a diterpene produced by Stemodia maritima L. (Scrophulariaceae) and shows antiviral and tumor cell proliferation inhibitory activities…”
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Effect of carrot juice on Haematococcus pluvialis growth and astaxanthin production
Published in Algal research (Amsterdam) (01-07-2024)“…In this work, we report the use of carrot juice (CJ) as a source of carotenoids as precursors of astaxanthin in a microalga Haematococcus pluvialis culture…”
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Immobilization of Amano lipase AK from Pseudomonas fluorescens on different types of chitosan-containing supports: use in the kinetic resolution of rac-indanol
Published in Bioprocess and biosystems engineering (01-04-2021)“…Amano lipase AK from P. fluorescens was immobilized on different types of chitosan-containing supports. Chitosan lower molecular weight (2.5%), chitosan lower…”
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Molecular docking study and antireabsorptive activity of a semi-synthetic coumarin derivative from Platymisciumfloribundum in the ligature-induced periodontitis in rats: the involvement of heme oxygenase-1
Published in Clinical oral investigations (01-02-2022)“…Objetive This study aimed to evaluate the anti-resorptive activity of a semi-synthetic coumarin derivative from Platymiscium floribundum , named…”
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Resolution of Racemic Aryloxy-Propan-2-yl Acetates via Lipase-Catalyzed Hydrolysis: Preparation of Enantiomerically Pure/Enantioenriched Mexiletine Intermediates and Analogs
Published in Catalysts (01-12-2022)“…The lipase kinetic resolution (KR) of aryloxy-propan-2-yl acetates, via hydrolysis, produced enantiomerically pure/enantioenriched mexiletine intermediates and…”
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The orange peel as biocatalyst for the hydrolysis of esters
Published in Industrial crops and products (01-06-2016)“…[Display omitted] •Orange peels in organic synthesis.•Plant as an alternative catalyst use in the hydrolysis of esters.•C. aurantium in the hydrolysis of…”
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Green Enzymatic Synthesis of Geranyl Butyrate: Process Optimization and Mechanistic Insights
Published in ACS omega (01-04-2024)“…Flavor esters are organic compounds widely used in the food industry to enhance the aroma and taste of products. However, most chemical processes for the…”
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Zingiber officinale (GINGER) AS AN ENZYME SOURCE FOR THE REDUCTION OF CARBONYL COMPOUNDS
Published in Química nova (01-05-2015)Get full text
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Immobilized Manihot esculenta preparation as a novel biocatalyst in the enantioselective acetylation of racemic alcohols
Published in Tetrahedron: asymmetry (30-06-2008)“…The enzymatic preparation obtained from a discard of Manihot esculenta roots has been successfully immobilized on calcium alginate hydrogels. This preparation…”
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Lens culinaris: A new biocatalyst for reducing carbonyl and nitro groups
Published in Biotechnology and bioprocess engineering (01-04-2012)“…A series of aliphatic and aromatic aldehydes and ketones, as well as some nitrocompounds were reduced using whole plant cells from Lens culinaris seeds. In…”
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Candida tropicalis CE017: a new Brazilian enzymatic source for the bioreduction of aromatic prochiral ketones
Published in Journal of the Brazilian Chemical Society (2010)“…The reactivity and stereoselectivity showed by a new strain of Candida tropicalis in the reduction of prochiral ketones have been compared with the ones…”
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Chemoenzymatic synthesis of (S)-Pindolol using lipases
Published in Applied catalysis. A, General (25-09-2017)“…[Display omitted] •A straightforward chemoenzymatic synthesis of (S)-Pindolol has been developed.•The key step involved kinetic lipase-mediated resolution of a…”
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Chemical modification of clay nanocomposites for the improvement of the catalytic properties of Lipase A from Candida antarctica
Published in Process biochemistry (1991) (01-09-2022)“…Kaolin is a mineral composed of hydrated aluminum silicates, clayey and with high bioavailability. The choice of this mineral as immobilization matrix took…”
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Esterases as stereoselective biocatalysts
Published in Biotechnology advances (01-09-2015)“…Non-lypolitic esterases are carboxylester hydrolases with preference for the hydrolysis of water-soluble esters bearing short-chain acyl residues. The…”
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Cashew apple bagasse as a support for the immobilization of lipase B from Candida antarctica: Application to the chemoenzymatic production of (R)-Indanol
Published in Journal of molecular catalysis. B, Enzymatic (01-08-2016)“…[Display omitted] •CALB immobilized on (CAB) activated then 1h with a 90% immobilization yield.•High thermal stability of CAB-AHP derivatives at temperatures…”
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