Search Results - "de Matos Guedes, Herbert L"

Effects of a Serine Protease Inhibitor N-p-Tosyl-L-phenylalanine Chloromethyl Ketone (TPCK) on Leishmania amazonensis and Leishmania infantum by Machado, Patrícia de A., Gomes, Pollyanna S., Carneiro, Monique P. D., Midlej, Victor, Coimbra, Elaine S., de Matos Guedes, Herbert L.

“…Studies have previously demonstrated the importance of serine proteases in Leishmania. A well-known serine protease inhibitor, TPCK, was used in the present…”
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Crosslinked chitosan microparticles as a safe and efficient DNA carrier for intranasal vaccination against cutaneous leishmaniasis by Costa Souza, Beatriz L.S., Pinto, Eduardo F., Bezerra, Izabella P.S., Gomes, Daniel C.O., Martinez, Ana Maria B., Ré, Maria Inês, de Matos Guedes, Herbert L., Rossi-Bergmann, Bartira

“…Intranasal (i.n.) vaccination with adjuvant-free plasmid DNA encoding the leishmanial antigen LACK (LACK DNA) has shown to induce protective immunity against…”
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Immunotherapy using anti-PD-1 and anti-PD-L1 in Leishmania amazonensis-infected BALB/c mice reduce parasite load by da Fonseca-Martins, Alessandra M., Ramos, Tadeu D., Pratti, Juliana E. S., Firmino-Cruz, Luan, Gomes, Daniel Claudio Oliveira, Soong, Lynn, Saraiva, Elvira M., de Matos Guedes, Herbert L.

“…Leishmaniasis is a neglected disease, for which current treatment presents numerous issues. Leishmania amazonensis is the etiological agent of cutaneous and…”
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Circulating Senescent T Cells Are Linked to Systemic Inflammation and Lesion Size During Human Cutaneous Leishmaniasis by Covre, Luciana P, Martins, Régia F, Devine, Oliver P, Chambers, Emma S, Vukmanovic-Stejic, Milica, Silva, Juliana A, Dietze, Reynaldo, Rodrigues, Rodrigo R, de Matos Guedes, Herbert L, Falqueto, Aloísio, Akbar, Arne N, Gomes, Daniel C O

“…induces American tegumentary leishmaniasis that ranges in severity from the milder form, cutaneous (CL) to severe disseminated cutaneous leishmaniasis…”
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Leishmania Parasites Drive PD-L1 Expression in Mice and Human Neutrophils With Suppressor Capacity by da Fonseca-Martins, Alessandra M., de Souza Lima-Gomes, Phillipe, Antunes, Maísa Mota, de Moura, Renan Garcia, Covre, Luciana P., Calôba, Carolina, Rocha, Vivian Grizente, Pereira, Renata M., Menezes, Gustavo Batista, Gomes, Daniel Claudio Oliveira, Saraiva, Elvira M., de Matos Guedes, Herbert L.

“…Neutrophils play an important role in the outcome of leishmaniasis, contributing either to exacerbating or controlling the progression of infection, a dual…”
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Subtilisin of Leishmania amazonensis as Potential Druggable Target: Subcellular Localization, In Vitro Leishmanicidal Activity and Molecular Docking of PF-429242, a Subtilisin Inhibitor by Gomes, Pollyanna Stephanie, Carneiro, Monique Pacheco Duarte, Machado, Patrícia de Almeida, de Andrade-Neto, Valter Viana, da Fonseca-Martins, Alessandra Marcia, Goundry, Amy, Pereira da Silva, João Vitor Marques, Gomes, Daniel Claudio Oliveira, Lima, Ana Paula Cabral de Araujo, Ennes-Vidal, Vítor, Sodero, Ana Carolina Rennó, De-Simone, Salvatore Giovanni, de Matos Guedes, Herbert L

“…Subtilisin proteases, found in all organisms, are enzymes important in the post-translational steps of protein processing. In Leishmania major and L. donovani,…”
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TLR9 Signaling Suppresses the Canonical Plasma Cell Differentiation Program in Follicular B Cells by Baptista, Bárbara José Antunes, Granato, Alessandra, Canto, Fábio B, Montalvão, Fabricio, Tostes, Lucas, de Matos Guedes, Herbert L, Coutinho, Antonio, Bellio, Maria, Vale, Andre M, Nobrega, Alberto

“…The relative potency and quality of mouse B cell response to Toll-like receptors (TLRs) signaling varies significantly depending on the B cell subset and on…”
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Vaccination With Recombinant Filamentous fd Phages Against Parasite Infection Requires TLR9 Expression by Gomes-Neto, João F, Sartorius, Rossella, Canto, Fábio B, Almeida, Thamyres S, Dias, André A, Barbosa, Carlos-Henrique D, Melo, Guilherme A, Oliveira, Ana Carolina, Aguiar, Pedro-Henrique N, Machado, Carlos R, de Matos Guedes, Herbert L, Santiago, Marcelo F, Nóbrega, Alberto, De Berardinis, Piergiuseppe, Bellio, Maria

“…Recombinant filamentous bacteriophages (r ) expressing antigenic peptides were shown to induce cell-mediated immune responses in the absence of added adjuvant,…”
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Eosinophils increase macrophage ability to control intracellular Leishmania amazonensis infection via PGD2 paracrine activity in vitro by da Silva Marques, Patrícia, da Fonseca-Martins, Alessandra M., Carneiro, Monique Pacheco Duarte, Amorim, Natália R.T., de Pão, Camila R. Rodrigues, Canetti, Claudio, Diaz, Bruno L., de Matos Guedes, Herbert L., Bandeira-Melo, Christianne

“…•Eosinophils enhance macrophage ability to control intracellular L. amazonensis infection in vitro.•Eosinophil-driven mechanism depends on a paracrine activity…”
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Oligopeptidase B-2 from Leishmania amazonensis with an unusual C-terminal extension by de Matos Guedes, Herbert L., de Carvalho, Rafael S. N., de Oliveira Gomes, Daniel C., Rossi-Bergmann, Bartira, De-Simone, Salvatore G.

“…The oligopeptidase B serine protease is an important virulence factor and therapeutic target in Trypanosoma infections. Recently, the Leishmania major Genome…”
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Oligopeptidase B and B2: comparative modelling and virtual screening as searching tools for new antileishmanial compounds by Sodero, Ana Carolina R, Dos Santos, Ana Carolina G O, Mello, Juliana F R E, DE Jesus, Jéssica B, DE Souza, Alessandra M T, Rodrigues, Maria Isabel C, DE Simone, Salvatore G, Rodrigues, Carlos R, DE Matos Guedes, Herbert L

“…Leishmaniasis are diseases caused by parasites of the genus Leishmania and transmitted to humans by the bite of infected insects of the subfamily…”
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Yellow fever vaccine protects mice against Zika virus infection by Ana C. Vicente Santos, Francisca H. Guedes-da-Silva, Carlos H. Dumard, Vivian N. S. Ferreira, Igor P. S. da Costa, Ruana A. Machado, Fernanda G. Q. Barros-Aragão, Rômulo L. S. Neris, Júlio S. dos-Santos, Iranaia Assunção-Miranda, Claudia P. Figueiredo, André A. Dias, Andre M. O. Gomes, Herbert L. de Matos Guedes, Andrea C. Oliveira, Jerson L. Silva

“…Zika virus (ZIKV) emerged as an important infectious disease agent in Brazil in 2016. Infection usually leads to mild symptoms, but severe congenital…”
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Yellow fever vaccine protects mice against Zika virus infection by Vicente Santos, Ana C, Guedes-da-Silva, Francisca H, Dumard, Carlos H, Ferreira, Vivian N S, da Costa, Igor P S, Machado, Ruana A, Barros-Aragão, Fernanda G Q, Neris, Rômulo L S, Dos-Santos, Júlio S, Assunção-Miranda, Iranaia, Figueiredo, Claudia P, Dias, André A, Gomes, Andre M O, de Matos Guedes, Herbert L, Oliveira, Andrea C, Silva, Jerson L

“…Zika virus (ZIKV) emerged as an important infectious disease agent in Brazil in 2016. Infection usually leads to mild symptoms, but severe congenital…”
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Intranasal vaccination with killed Leishmania amazonensis promastigotes antigen (LaAg) associated with CAF01 adjuvant induces partial protection in BALB/c mice challenged with Leishmania (infantum) chagasi by Leal, Janine Miranda, Mosquini, Marcelle, Covre, Luciana Polaco, Stagmiller, Nataly Pescinalli, Rodrigues, Rodrigo Ribeiro, Christensen, Dennis, de Matos Guedes, Herbert Leonel, Guedes, Herbert Leonel De Matos, Rossi-Bergmann, Bartira, Gomes, Daniel Cláudio De Oliviera

“…The CAF01 adjuvant has previously been shown to be safe for human use and to be a potent adjuvant for several vaccine antigens. In the present work, we sought…”
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Eosinophils increase macrophage ability to control intracellular Leishmania amazonensis infection via PGD 2 paracrine activity in vitro by da Silva Marques, Patrícia, da Fonseca-Martins, Alessandra M, Carneiro, Monique Pacheco Duarte, Amorim, Natália R T, de Pão, Camila R Rodrigues, Canetti, Claudio, Diaz, Bruno L, de Matos Guedes, Herbert L, Bandeira-Melo, Christianne

“…Clinical and experimental studies have described eosinophil infiltration in Leishmania amazonensis infection sites, positioning eosinophils strategically…”
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