Search Results - "de Matos, Ana M."
-
1
Alkyl deoxyglycoside-polymyxin combinations against critical priority carbapenem-resistant gram-negative bacteria
Published in Scientific reports (26-01-2024)“…The escalating antimicrobial resistance crisis urges the development of new antibacterial treatments with innovative mechanisms of action, particularly against…”
Get full text
Journal Article -
2
Antibacterial Prodrugs to Overcome Bacterial Antimicrobial Resistance
Published in Pharmaceuticals (Basel, Switzerland) (01-06-2024)“…Antimicrobial resistance (AMR) is an increasingly concerning phenomenon that requires urgent attention because it poses a threat to human and animal health…”
Get full text
Journal Article -
3
Recent antibacterial carbohydrate-based prodrugs, drugs and delivery systems to overcome antimicrobial resistance
Published in Current opinion in chemical biology (01-02-2024)“…Antimicrobial resistance is an increasing phenomenon that is threatening global health. Tuberculosis causative bacteria and several resistant and…”
Get full text
Journal Article -
4
Design and Synthesis of CNS-targeted Flavones and Analogues with Neuroprotective Potential Against H2O2- and Aβ1-42-Induced Toxicity in SH-SY5Y Human Neuroblastoma Cells
Published in Pharmaceuticals (Basel, Switzerland) (21-06-2019)“…With the lack of available drugs able to prevent the progression of Alzheimer’s disease (AD), the discovery of new neuroprotective treatments able to rescue…”
Get full text
Journal Article -
5
Glucosylpolyphenols as Inhibitors of Aβ-Induced Fyn Kinase Activation and Tau Phosphorylation: Synthesis, Membrane Permeability, and Exploratory Target Assessment within the Scope of Type 2 Diabetes and Alzheimer’s Disease
Published in Journal of medicinal chemistry (22-10-2020)“…Despite the rapidly increasing number of patients suffering from type 2 diabetes, Alzheimer’s disease, and diabetes-induced dementia, there are no…”
Get full text
Journal Article -
6
Impact of the COVID-19 pandemic on the breast cancer early diagnosis program in Brazil
Published in Preventive medicine reports (01-04-2023)“…During the COVID-19 pandemic, several screening exams were postponed, including mammograms. The aim of this study was to evaluate the impact of COVID-19 in…”
Get full text
Journal Article -
7
Exploring Anti-Prion Glyco-Based and Aromatic Scaffolds: A Chemical Strategy for the Quality of Life
Published in Molecules (Basel, Switzerland) (24-05-2017)“…Prion diseases are fatal neurodegenerative disorders caused by protein misfolding and aggregation, affecting the brain progressively and consequently the…”
Get full text
Journal Article -
8
Design and Synthesis of CNS-targeted Flavones and Analogues with Neuroprotective Potential Against H 2 O 2 - and Aβ 1-42 -Induced Toxicity in SH-SY5Y Human Neuroblastoma Cells
Published in Pharmaceuticals (Basel, Switzerland) (21-06-2019)“…With the lack of available drugs able to prevent the progression of Alzheimer's disease (AD), the discovery of new neuroprotective treatments able to rescue…”
Get full text
Journal Article