Search Results - "de Martin, R."

CD40L and TNF both activate the classical NF-κB pathway, which is not required for the CD40L induced alternative pathway in endothelial cells by Seigner, J., Basilio, J., Resch, U., de Martin, R.

“…CD40L and TNF signal through engagement of their respective receptors, which are both members of the TNF receptor family. They use partially common signaling…”
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Self-medication by orang-utans (Pongo pygmaeus) using bioactive properties of Dracaena cantleyi by Morrogh-Bernard, H. C., Foitová, I., Yeen, Z., Wilkin, P., de Martin, R., Rárová, L., Doležal, K., Nurcahyo, W., Olšanský, M.

“…Animals self-medicate using a variety of plant and arthropod secondary metabolites by either ingesting them or anointing them to their fur or skin apparently…”
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Bird nest orientation and local temperature: an analysis over three decades by Schaaf, Alejandro A., de la Peña, Martin R.

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TOUCAN 2: the all-inclusive open source workbench for regulatory sequence analysis by Aerts, Stein, Van Loo, Peter, Thijs, Gert, Mayer, Herbert, de Martin, Rainer, Moreau, Yves, De Moor, Bart

“…We present the second and improved release of the TOUCAN workbench for cis-regulatory sequence analysis. TOUCAN implements and integrates fast state-of-the-art…”
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Bifunctional bisphosphonate complexes for the diagnosis and therapy of bone metastases by Torres Martin de Rosales, R, Finucane, C, Mather, S J, Blower, P J

“…Easily synthesised and structurally well-defined novel imaging/therapeutic radiopharmaceutical agents for bone metastases are described…”
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α-Catulin, a Rho signalling component, can regulate NF-κB through binding to IKK-β, and confers resistance to apoptosis by Wiesner, C, Winsauer, G, Resch, U, Hoeth, M, Schmid, J A, van Hengel, J, van Roy, F, Binder, B R, de Martin, R

“…Rho GTPases regulate diverse cellular functions including adhesion, cytokinesis and motility, as well as the activity of the transcription factors NF-κB, serum…”
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Inhibition of endothelial cell activation by adenovirus-mediated expression of I kappa B alpha, an inhibitor of the transcription factor NF-kappa B by Wrighton, C J, Hofer-Warbinek, R, Moll, T, Eytner, R, Bach, F H, de Martin, R

“…During the inflammatory response, endothelial cells (EC) transiently upregulate a set of genes encoding, among others, cell adhesion molecules and chemotactic…”
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Cytokine‐inducible expression in endothelial cells of an I kappa B alpha‐like gene is regulated by NF kappa B by Martin, R., Vanhove, B., Cheng, Q., Hofer, E., Csizmadia, V., Winkler, H., Bach, F.H.

“…The transient expression of many different genes is mediated by the inducible transcription factor p50‐p65 NF kappa B, which in turn is regulated by complex…”
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Anti-inflammatory gene therapy directed at the airway epithelium by GRIESENBACH, U, SCHEID, P, HILLERY, E, DE MARTIN, R, HUANG, L, GEDDES, D. M, ALTON, E. W. F. W

“…Cystic fibrosis (CF) is characterised by chronic airway inflammation. Pro-inflammatory mediators in the lung are regulated by the transcription factor nuclear…”
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Interleukin‐33 induces urokinase in human endothelial cells―possible impact on angiogenesis by Stojkovic, S., Kaun, C., Heinz, M., Krychtiuk, K. A., Rauscher, S., Lemberger, C. E., Martin, R., Gröger, M., Petzelbauer, P., Huk, I., Huber, K., Wojta, J., Demyanets, S.

“…Summary Background Urokinase‐type plasminogen activator (u‐PA) plays a pivotal role in extracellular proteolysis and is thought to be critically involved in…”
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Bay11-7082 inhibits the disintegration of the lymphendothelial barrier triggered by MCF-7 breast cancer spheroids; the role of ICAM-1 and adhesion by Viola, K, Kopf, S, Huttary, N, Vonach, C, Kretschy, N, Teichmann, M, Giessrigl, B, Raab, I, Stary, S, Krieger, S, Keller, T, Bauer, S, Hantusch, B, Szekeres, T, de Martin, R, Jäger, W, Mikulits, W, Dolznig, H, Krupitza, G, Grusch, M

“…Background: Many cancers spread through lymphatic routes, and mechanistic insights of tumour intravasation into the lymphatic vasculature and targets for…”
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The Transcription Factor NF-κB and the Regulation of Vascular Cell Function by de Martin, Rainer, Hoeth, Martina, Hofer-Warbinek, Renate, Schmid, Johannes A

“…A variety of pathophysiological situations that affect cells of the vasculature, including endothelial and smooth muscle cells, leads to the expression of…”
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Pharmacological insight into the anti-inflammatory activity of sesquiterpene lactones from Neurolaena lobata (L.) R.Br. ex Cass by McKinnon, R., Binder, M., Zupkó, I., Afonyushkin, T., Lajter, I., Vasas, A., de Martin, R., Unger, C., Dolznig, H., Diaz, R., Frisch, R., Passreiter, C.M., Krupitza, G., Hohmann, J., Kopp, B., Bochkov, V.N.

“…Neurolaena lobata is a Caribbean medicinal plant used for the treatment of several conditions including inflammation. Recent data regarding potent…”
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Specificity, diversity, and convergence in VEGF and TNF‐α signaling events leading to tissue factor up regulation via EGR‐1 in endothelial cells by MECHTCHERIAKOVA, DIANA, SCHABBAUER, GERNOT, LUCERNA, MARKUS, CLAUSS, MATTHIAS, MARTIN, RAINER DE, BINDER, BERND R., HOFER, ERHARD

“…ABSTRACT Tissue factor (TF) has been shown to be up‐regulated in endothelial cells by the inflammatory cytokine tumor necrosis factor a (TNF‐α) as well as by…”
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IKKβ‐dependent NF‐κB pathway controls vascular inflammation and intimal hyperplasia by Bu, De‐Xiu, Erl, Wolfgang, De Martin, Rainer, Hansson, Göran K., Yan, Zhong‐Qun

“…ABSTRACTNuclear factor‐κB (NF‐κB)‐mediated vascular inflammation is a prominent characteristic of atherogenesis and restenosis. We noted that angioplastic…”
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Macrophage colony stimulating factor expression in human cardiac cells is upregulated by tumor necrosis factor‐α via an NF‐κB dependent mechanism by HOHENSINNER, P. J., KAUN, C., RYCHLI, K., NIESSNER, A., PFAFFENBERGER, S., REGA, G., De MARTIN, R., MAURER, G., ULLRICH, R., HUBER, K., WOJTA, J.

“…Introduction: Macrophage colony stimulating factor (M‐CSF) is a key factor for monocyte and macrophage survival and proliferation. M‐CSF has been implicated in…”
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Adenovirus-mediated expression of green fluorescent protein by DE MARTIN, R, RAIDL, M, HOFER, E, BINDER, B. R

“…A recombinant replication-deficient adenovirus has been generated that expresses a mutant of the Aquorea victoria green fluorescent protein (GFP) under the…”
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Nuclear Factor-kappa B Regulates Induction of Apoptosis and Inhibitor of Apoptosis Protein-1 Expression in Vascular Smooth Muscle Cells by Erl, Wolfgang, Hansson, Goran K, de Martin, Rainer, Draude, Georg, Weber, Kim S.C, Weber, Christian

“…Apoptosis is important in normal development as well as in diseases such as atherosclerosis. However, the regulation of apoptosis is still not completely…”
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Activation of nuclear factor-κB significantly contributes to lumen loss in a rabbit iliac artery balloon angioplasty model by BREUSS, J. M, CEJNA, M, LOSERT, U, LAMMER, J, BINDER, B. R, BERGMEISTER, H, KADL, A, BAUMGARTL, G, STEURER, S, XU, Z, KOSHELNICK, Y, LIPP, J, DE MARTIN, R

“…To investigate the contribution of inflammation to postangioplasty lumen loss, we used an adenoviral gene therapy approach to inhibit the central inflammatory…”
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A highly conserved proapoptotic gene, IKIP, located next to the APAF1 gene locus, is regulated by p53 by Hofer-Warbinek, R, Schmid, J A, Mayer, H, Winsauer, G, Orel, L, Mueller, B, Wiesner, Ch, Binder, B R, de Martin, R

“…We describe here the identification and initial characterization of a novel human gene termed IKIP (I kappa B kinase interacting protein) that is located on…”
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