Search Results - "de Marañón, Aranzazu M"

The Role of Mitochondrial Dynamic Dysfunction in Age-Associated Type 2 Diabetes by Vezza, Teresa, Díaz-Pozo, Pedro, Canet, Francisco, de Marañón, Aranzazu M, Abad-Jiménez, Zaida, García-Gargallo, Celia, Roldan, Ildefonso, Solá, Eva, Bañuls, Celia, López-Domènech, Sandra, Rocha, Milagros, Víctor, Víctor M

“…Mitochondrial dynamics, such as fusion and fission, play a critical role in maintaining cellular metabolic homeostasis. The molecular mechanisms underlying…”
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Does Metformin Modulate Mitochondrial Dynamics and Function in Type 2 Diabetic Patients? by de Marañón, Aranzazu M, Canet, Francisco, Abad-Jiménez, Zaida, Jover, Ana, Morillas, Carlos, Rocha, Milagros, Victor, Victor M

“…Metformin is an effective drug against type 2 diabetes (T2D), a pathogenesis in which mitochondrial dysfunction is one of the main players. Thus, our first aim…”
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Low testosterone levels are related to oxidative stress, mitochondrial dysfunction and altered subclinical atherosclerotic markers in type 2 diabetic male patients by Rovira-Llopis, Susana, Bañuls, Celia, de Marañon, Aranzazu M., Diaz-Morales, Noelia, Jover, Ana, Garzon, Sandra, Rocha, Milagros, Victor, Victor M., Hernandez-Mijares, Antonio

“…Low testosterone levels in men are associated with type 2 diabetes and cardiovascular risk. However, the role of testosterone in mitochondrial function and…”
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The SGLT2 Inhibitor Empagliflozin Ameliorates the Inflammatory Profile in Type 2 Diabetic Patients and Promotes an Antioxidant Response in Leukocytes by Iannantuoni, Francesca, M de Marañon, Aranzazu, Diaz-Morales, Noelia, Falcon, Rosa, Bañuls, Celia, Abad-Jimenez, Zaida, Victor, Victor M, Hernandez-Mijares, Antonio, Rovira-Llopis, Susana

“…Sodium-glucose co-transporter 2 inhibitors (iSGLT2) have been linked to a considerable reduction in cardiovascular risk in patients with type 2 diabetes (T2D),…”
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The mitochondrial antioxidant SS-31 increases SIRT1 levels and ameliorates inflammation, oxidative stress and leukocyte-endothelium interactions in type 2 diabetes by Escribano-Lopez, Irene, Diaz-Morales, Noelia, Iannantuoni, Francesca, Lopez-Domenech, Sandra, de Marañon, Aranzazu M, Abad-Jimenez, Zaida, Bañuls, Celia, Rovira-Llopis, Susana, Herance, Jose R, Rocha, Milagros, Victor, Victor M

“…There is growing focus on mitochondrial impairment and cardiovascular diseases (CVD) in type 2 diabetes (T2D), and the development of novel therapeutic…”
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Metformin modulates mitochondrial function and mitophagy in peripheral blood mononuclear cells from type 2 diabetic patients by de Marañón, Aranzazu M., Díaz-Pozo, Pedro, Canet, Francisco, Díaz-Morales, Noelia, Abad-Jiménez, Zaida, López-Domènech, Sandra, Vezza, Teresa, Apostolova, Nadezda, Morillas, Carlos, Rocha, Milagros, Víctor, Víctor M.

“…Type 2 diabetes is a chronic metabolic disease that affects mitochondrial function. In this context, the rescue mechanisms of mitochondrial health, such as…”
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Phytosterols: Nutritional Health Players in the Management of Obesity and Its Related Disorders by Vezza, Teresa, Canet, Francisco, de Marañón, Aranzazu M, Bañuls, Celia, Rocha, Milagros, Víctor, Víctor Manuel

“…Obesity and its related disorders, such as diabetes and cardiovascular risk, represent an emerging global health issue. Even though genetic factors seem to be…”
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Malnutrition impairs mitochondrial function and leukocyte activation by Bañuls, Celia, de Marañon, Aranzazu M, Veses, Silvia, Castro-Vega, Iciar, López-Domènech, Sandra, Salom-Vendrell, Christian, Orden, Samuel, Álvarez, Ángeles, Rocha, Milagros, Víctor, Víctor M, Hernández-Mijares, Antonio

“…The aim of this study was to evaluate markers of inflammation, oxidative stress and endothelial function in a disease-related malnutrition (DRM) outpatient…”
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MicroRNAs and Oxidative Stress: An Intriguing Crosstalk to Be Exploited in the Management of Type 2 Diabetes by Vezza, Teresa, de Marañón, Aranzazu M., Canet, Francisco, Díaz-Pozo, Pedro, Marti, Miguel, D’Ocon, Pilar, Apostolova, Nadezda, Rocha, Milagros, Víctor, Víctor M.

“…Type 2 diabetes is a chronic disease widespread throughout the world, with significant human, social, and economic costs. Its multifactorial etiology leads to…”
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Relationship between PMN-endothelium interactions, ROS production and Beclin-1 in type 2 diabetes by De Marañon, Aranzazu M., Iannantuoni, Francesca, Abad-Jiménez, Zaida, Canet, Francisco, Díaz-Pozo, Pedro, López-Domènech, Sandra, Jover, Ana, Morillas, Carlos, Mariño, Guillermo, Apostolova, Nadezda, Rocha, Milagros, Victor, Victor M.

“…Type 2 diabetes is closely related to oxidative stress and cardiovascular diseases. In this study, we hypothesized that polymorphonuclear leukocytes…”
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Mitochondrial Alterations and Enhanced Human Leukocyte/Endothelial Cell Interactions in Type 1 Diabetes by Iannantuoni, Francesca, M. de Marañon, Aranzazu, Abad-Jiménez, Zaida, Canet, Francisco, Díaz-Pozo, Pedro, López-Domènech, Sandra, Morillas, Carlos, Rocha, Milagros, Víctor, Víctor M.

“…Type 1 diabetes has been associated with oxidative stress. This study evaluates the rates of oxidative stress, mitochondrial function, leukocyte–endothelium…”
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Role of Endoplasmic Reticulum and Oxidative Stress Parameters in the Pathophysiology of Disease-Related Malnutrition in Leukocytes of an Outpatient Population by Bañuls, Celia, de Marañón, Aranzazu M, Castro-Vega, Iciar, López-Doménech, Sandra, Escribano-López, Irene, Salom, Christian, Veses, Silvia, Hernández-Mijares, Antonio

“…Cellular pathways such as inflammation or oxidative stress are the cause and triggers of disease-related malnutrition (DRM), but the influence of these markers…”
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The Mitochondrial Antioxidant SS-31 Modulates Oxidative Stress, Endoplasmic Reticulum Stress, and Autophagy in Type 2 Diabetes by Escribano-López, Irene, de Marañon, Aranzazu M, Iannantuoni, Francesca, López-Domènech, Sandra, Abad-Jiménez, Zaida, Díaz, Pedro, Solá, Eva, Apostolova, Nadezda, Rocha, Milagros, Víctor, Víctor M

“…Mitochondrial dysfunction has been shown to play a central role in the pathophysiology of type 2 diabetes (T2D), and mitochondria-targeted agents such as SS-31…”
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Effect of Roux-en-Y Bariatric Bypass Surgery on Subclinical Atherosclerosis and Oxidative Stress Markers in Leukocytes of Obese Patients: A One-Year Follow-Up Study by Abad-Jiménez, Zaida, López-Domènech, Sandra, Gómez-Abril, Segundo Ángel, Periañez-Gómez, Dolores, de Marañón, Aranzazu M., Bañuls, Celia, Morillas, Carlos, Víctor, Víctor M., Rocha, Milagros

“…Little is known about the mechanisms underlying the cardioprotective effect of Roux en-Y gastric bypass (RYGB) surgery. Therefore, the aim of the present study…”
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Pinitol alleviates systemic inflammatory cytokines in human obesity by a mechanism involving unfolded protein response and sirtuin 1 by López-Domènech, Sandra, Bañuls, Celia, de Marañón, Aranzazu M., Abab-Jiménez, Zaida, Morillas, Carlos, Gómez-Abril, Segundo Ángel, Rovira-Llopis, Susana, Víctor, Víctor Manuel, Hernández-Mijares, Antonio, Rocha, Milagros

“…It is known that pinitol acts as a mediator of the insulin-signaling pathway, though little is known about its anti-inflammatory effect in human obesity…”
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Targeting mitochondria: a great boon to fight type 2 diabetes by de Marañón, Aranzazu M, Rovira-Llopis, Susana, Rocha, Milagros, Víctor, Víctor M

“…Type 2 diabetes is a chronic metabolic disease characterized by the development of low-grade systemic inflammation, hyperglycaemia, and hyperlipidaemia. These…”
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Moderate weight loss attenuates chronic endoplasmic reticulum stress and mitochondrial dysfunction in human obesity by López-Domènech, Sandra, Abad-Jiménez, Zaida, Iannantuoni, Francesca, de Marañón, Aranzazu M., Rovira-Llopis, Susana, Morillas, Carlos, Bañuls, Celia, Víctor, Víctor Manuel, Rocha, Milagros

“…In obese patients undergoing caloric restriction, there are several potential mechanisms involved in the improvement of metabolic outcomes. The present study…”
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Metformin reduces mitochondrial ROS levels and improves mitochondrial mass, membrane potential and respiratory complexes in leukocytes of type 2 diabetic subjects by de Marañón, Aranzazu M., Díaz-Pozo, Pedro, Canet, Francisco, Vezza, Teresa, Abad-Jiménez, Zaida, López-Domènech, Sandra, Falcón, Rosa, Bañuls, Celia, Rocha, Milagros, Víctor, Víctor M.

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Metformin treatment reduces ROS levels, improves mitochondrial function and dynamics in leukocytes from type 2 diabetic patients by de Marañón, Aranzazu M., Díaz, Pedro, Canet, Francisco, Abad-Jiménez, Zaida, García, Celia, Falcón, Rosa, Bañuls, Celia, López-Domènech, Sandra, Vezza, Teresa, Navarro, Blanca, Roldán, Ildefonso, Mora, Vicente, Morillas, Carlos, Rocha, Milagros, Víctor, Víctor M.

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Empagliflozin Treatment Ameliorates the Inflammatory Profile of type 2 Diabetic Patients and reduce NFkB Expression by Promoting an Antioxidant Response in Leukocytes by Canet, Francisco, de Marañón, Aranzazu M., Díaz-Pozo, Pedro, Iannantuoni, Francesca, Vezza, Teresa, Abad-Jiménez, Zaida, López-Domènech, Sandra, Falcón, Rosa, Zaragozá, Begoña, Bañuls, Celia, Sola, Eva, Morillas, Carlos, Rocha, Milagros, Víctor, Víctor M.

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