Search Results - "de Magalhaes Filho, C Daniel"

Signaling Networks Determining Life Span by Riera, Celine E, Merkwirth, Carsten, De Magalhaes Filho, C. Daniel, Dillin, Andrew

“…The health of an organism is orchestrated by a multitude of molecular and biochemical networks responsible for ensuring homeostasis within cells and tissues…”
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Visible light reduces C. elegans longevity by De Magalhaes Filho, C. Daniel, Henriquez, Brian, Seah, Nicole E., Evans, Ronald M., Lapierre, Louis R., Dillin, Andrew

“…The transparent nematode Caenorhabditis elegans can sense UV and blue-violet light to alter behavior. Because high-dose UV and blue-violet light are not a…”
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Farnesoid X Receptor an Emerging Target to Combat Obesity by De Magalhaes Filho, C Daniel, Downes, Michael, Evans, Ronald M

“…Obesity and its associated diseases, including type 2 diabetes, have reached epidemic levels worldwide. However, available treatment options are limited and…”
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Deleting IGF-1 receptor from forebrain neurons confers neuroprotection during stroke and upregulates endocrine somatotropin by De Magalhaes Filho, C Daniel, Kappeler, Laurent, Dupont, Joëlle, Solinc, Julien, Villapol, Sonia, Denis, Cécile, Nosten-Bertrand, Marika, Billard, Jean-Marie, Blaise, Annick, Tronche, François, Giros, Bruno, Charriaut-Marlangue, Christiane, Aïd, Saba, Le Bouc, Yves, Holzenberger, Martin

“…Insulin-like growth factors control numerous processes, namely somatic growth, metabolism and stress resistance, connecting this pathway to aging and…”
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Cancer-targeted photoimmunotherapy induces antitumor immunity and can be augmented by anti-PD-1 therapy for durable anticancer responses in an immunologically active murine tumor model by Hsu, Michelle A., Okamura, Stephanie M., De Magalhaes Filho, C. Daniel, Bergeron, Daniele M., Rodriguez, Ahiram, West, Melissa, Yadav, Deepak, Heim, Roger, Fong, Jerry J., Garcia-Guzman, Miguel

“…The complex immunosuppressive nature of solid tumor microenvironments poses a significant challenge to generating efficacious and durable anticancer responses…”
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ERRγ Preserves Brown Fat Innate Thermogenic Activity by Ahmadian, Maryam, Liu, Sihao, Reilly, Shannon M., Hah, Nasun, Fan, Weiwei, Yoshihara, Eiji, Jha, Pooja, De Magalhaes Filho, C. Daniel, Jacinto, Sandra, Gomez, Andrew V., Dai, Yang, Yu, Ruth T., Liddle, Christopher, Atkins, Annette R., Auwerx, Johan, Saltiel, Alan R., Downes, Michael, Evans, Ronald M.

“…Brown adipose tissue (BAT) adaptively transfers energy from glucose and fat into heat by inducing a gene network that uncouples mitochondrial electron…”
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The TFEB orthologue HLH-30 regulates autophagy and modulates longevity in Caenorhabditis elegans by Lapierre, Louis R., De Magalhaes Filho, C. Daniel, McQuary, Philip R., Chu, Chu-Chiao, Visvikis, Orane, Chang, Jessica T., Gelino, Sara, Ong, Binnan, Davis, Andrew E., Irazoqui, Javier E., Dillin, Andrew, Hansen, Malene

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Exploring endocrine GH pattern in mice using rank plot analysis and random blood samples by Xu, Jie, Bekaert, Amaury Jean-Marie, Dupont, Joëlle, Rouve, Sarah, Annesi-Maesano, Isabella, De Magalhaes Filho, C Daniel, Kappeler, Laurent, Holzenberger, Martin

“…GH plays important pleiotropic roles in development, growth, metabolism, and aging of vertebrate species. Mouse mutants with altered GH signaling have been…”
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The TFEB orthologue HLH-30 regulates autophagy and modulates longevity in Caenorhabditis elegans by Lapierre, Louis R., De Magalhaes Filho, C. Daniel, McQuary, Philip R., Chu, Chu-Chiao, Visvikis, Orane, Chang, Jessica T., Gelino, Sara, Ong, Binnan, Davis, Andrew E., Irazoqui, Javier E., Dillin, Andrew, Hansen, Malene

“…Autophagy is a cellular recycling process that has an important anti-aging role, but the underlying molecular mechanism is not well understood. The mammalian…”
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Bile Acid Analog Intercepts Liver Fibrosis by De Magalhaes Filho, C. Daniel, Downes, Michael, Evans, Ron

“…Ocaliva, a synthetic bile acid analog with high affinity for the nuclear bile acid receptor FXR, is effective in treating primary biliary cholangitis, an…”
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Autophagy-mediated longevity is modulated by lipoprotein biogenesis by Seah, Nicole E, de Magalhaes Filho, C Daniel, Petrashen, Anna P, Henderson, Hope R, Laguer, Jade, Gonzalez, Julissa, Dillin, Andrew, Hansen, Malene, Lapierre, Louis R

“…Autophagy-dependent longevity models in C. elegans display altered lipid storage profiles, but the contribution of lipid distribution to life-span extension is…”
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622 PD-L1 is a potential predictive biomarker for response to RM-1929 treatment in recurrent head and neck squamous cell carcinoma patients by De Magalhaes Filho, C Daniel, Lee, Chung-Wein, Suslov, Nikolai, Fong, Jerry, Garcia-Guzman, Miguel

“…BackgroundRM-1929 is an antibody-dye conjugate comprised of cetuximab covalently linked to the photoactivable dye, IRDye® 700DX (IR700). After systemic…”
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Abstract 1798: CTLA-4 photoimmunotherapy depletes intratumoral regulatory T cells (Tregs) to augment local and systemic immunity for anticancer activity by Filho, C. Daniel de Magalhaes, Okamura, Stephanie M., Bergeron, Daniele M., Rodriguez, Ahiram, Lozano, Abram, Fong, Jerry J., Garcia-Guzman, Miguel

“…Abstract Introduction: Photoimmunotherapy is an investigational cancer treatment platform that utilizes an antibody conjugated to a light activated dye IRDye®…”
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Abstract 949: Anti-cancer activity by photoimmunotherapy is driven by adaptive immune responses and vaccinates the host against the tumor by De Magalhaes Filho, C. Daniel, Hsu, Michelle A., Okamura, Stephanie M., Gitnick, Dany, Solis, Estela, Fong, Jerry J., Garcia-Guzman, Miguel

“…Abstract INTRODUCTION: Photoimmunotherapy (PIT) is an investigational anti-cancer treatment platform utilizing cell-targeted antibodies conjugated to the IR700…”
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Deleting IGF-1 receptor from forebrain neurons confers neuroprotection during stroke and upregulates endocrine somatotropin by de Magalhaes Filho, C Daniel, Kappeler, Laurent, Dupont, Joëlle, Solinc, Julien, Villapol, Sonia, Denis, Cécile, Nosten-Bertrand, Marika, Billard, Jean-Marie, Blaise, Annick, Tronche, François, Giros, Bruno, Charriaut-Marlangue, Christiane, Aïd, Saba, Le Bouc, Yves, Holzenberger, Martin

“…Insulin-like growth factors control numerous processes, namely somatic growth, metabolism and stress resistance, connecting this pathway to aging and…”
Get full text

Deleting IGF-1 receptor from forebrain neurons confers neuroprotection during stroke and upregulates endocrine somatotropin by de Magalhaes Filho, C Daniel, Kappeler, Laurent, Dupont, Joëlle, Solinc, Julien, Villapol, Sonia, Denis, Cecile, Nosten-Bertrand, Marika, Billard, Jean-Marie, Blaise, Annick, Tronche, Francois, Giros, Bruno, Charriaut-Marlangue, Christiane, Aïd, Saba, Le Bouc, Yves, Holzenberger, Martin

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Autophagy-mediated longevity is modulated by lipoprotein biogenesis by Seah, Nicole E., de Magalhaes Filho, C. Daniel, Petrashen, Anna P., Henderson, Hope R., Laguer, Jade, Gonzalez, Julissa, Dillin, Andrew, Hansen, Malene, Lapierre, Louis R.

“…Autophagy-dependent longevity models in C. elegans display altered lipid storage profiles, but the contribution of lipid distribution to life-span extension is…”
Get full text