Search Results - "de Lima Menezes, Gabriela"

Quantum mechanics insights into melatonin and analogs binding to melatonin MT1 and MT2 receptors by de Lima Menezes, Gabriela, Sales Bezerra, Katyanna, Nobre Oliveira, Jonas Ivan, Fontenele Araújo, John, Soares Galvão, Douglas, Alves da Silva, Roosevelt, Vogel Saivish, Marielena, Laino Fulco, Umberto

“…Melatonin receptors MT 1 and MT 2 are G protein-coupled receptors that mediate the effects of melatonin, a hormone involved in circadian rhythms and other…”
Get full text

Antiviral Activity of Quercetin Hydrate against Zika Virus by Saivish, Marielena Vogel, Menezes, Gabriela de Lima, da Silva, Roosevelt Alves, Fontoura, Marina Alves, Shimizu, Jacqueline Farinha, da Silva, Gislaine Celestino Dutra, Teixeira, Igor da Silva, Mistrão, Natalia Franco Bueno, Hernandes, Victor Miranda, Rahal, Paula, Sacchetto, Lívia, Pacca, Carolina Colombelli, Marques, Rafael Elias, Nogueira, Maurício Lacerda

“…Zika virus (ZIKV) has re-emerged in recent decades, leading to outbreaks of Zika fever in Africa, Asia, and Central and South America. Despite its drastic…”
Get full text

Predicting Antigenic Peptides from Rocio Virus NS1 Protein for Immunodiagnostic Testing Using Immunoinformatics and Molecular Dynamics Simulation by Saivish, Marielena Vogel, Menezes, Gabriela de Lima, Costa, Vivaldo Gomes da, Silva, Gislaine Celestino Dutra da, Marques, Rafael Elias, Nogueira, Maurício Lacerda, Silva, Roosevelt Alves Da

“…The mosquito-borne disease caused by the Rocio virus is a neglected threat, and new immune inputs for serological testing are urgently required for diagnosis…”
Get full text

Rocio Virus: An Updated View on an Elusive Flavivirus by Saivish, Marielena Vogel, Gomes da Costa, Vivaldo, de Lima Menezes, Gabriela, Alves da Silva, Roosevelt, Dutra da Silva, Gislaine Celestino, Moreli, Marcos Lázaro, Sacchetto, Livia, Pacca, Carolina Colombelli, Vasilakis, Nikos, Nogueira, Maurício Lacerda

“…Rocio virus (ROCV) is a mosquito-borne flavivirus and human pathogen. The virus is indigenous to Brazil and was first detected in 1975 in the Sao Paulo State,…”
Get full text

Antiviral Activity and Molecular Dynamics Simulation of Hops Compounds against Oropouche Virus ( Peribunyaviridae ) by Mandova, Tsvetelina, Saivish, Marielena Vogel, Menezes, Gabriela de Lima, Bezerra, Katyanna Sales, Fulco, Umberto Laino, da Silva, Roosevelt Alves, Da Costa, Fernando Batista, Nogueira, Maurício Lacerda

“…The Oropouche virus (OROV) is a member of the family (order ) and the cause of a dengue-like febrile illness transmitted mainly by biting midges and…”
Get full text

Structural Insights into Plasticity and Discovery of Flavonoid Allosteric Inhibitors of Flavivirus NS2B–NS3 Protease by Saivish, Marielena Vogel, Menezes, Gabriela de Lima, Costa, Vivaldo Gomes da, Nebo, Liliane, Silva, Gislaine Celestino Dutra da, Pacca, Carolina Colombelli, Marques, Rafael Elias, Nogueira, Maurício Lacerda, Da Silva, Roosevelt Alves

“…Flaviviruses are among the most critical pathogens in tropical regions; they cause various severe diseases in developing countries but are not restricted to…”
Get full text

Mycobacterium bovis PknG R242P Mutation Results in Structural Changes with Enhanced Virulence in the Mouse Model of Infection by Oliveira, Fábio Muniz de, Procopio, Victor Oliveira, de Lima Menezes, Gabriela, Silva, Roosevelt Alves da, Kipnis, André, Junqueira-Kipnis, Ana Paula

“…is the causative agent of tuberculosis in domestic and wild animal species and sometimes in humans, presenting variable degrees of pathogenicity. It is known…”
Get full text

Exploring Quercetin Hydrate’s Potential as an Antiviral Treatment for Oropouche Virus by Menezes, Gabriela de Lima, Saivish, Marielena Vogel, Sacchetto, Lívia, da Silva, Gislaine Celestino Dutra, Teixeira, Igor da Silva, Mistrão, Natalia Franco Bueno, Nogueira, Maurício Lacerda, Oliveira, Jonas Ivan Nobre, Bezerra, Katyanna Sales, da Silva, Roosevelt Alves, Fulco, Umberto Laino

“…The Oropouche virus is an orthobunyavirus responsible for causing Oropouche fever, a disease that primarily affects thousands of people in South and Central…”
Get full text

Virtual screening of small natural compounds against NS1 protein of DENV, YFV and ZIKV by de Lima Menezes, Gabriela, Vogel Saivish, Marielena, Lacerda Nogueira, Maurício, Alves da Silva, Roosevelt

“…Diseases caused by viruses of the genus Flavivirus are among the main diseases that affect the world and they are a serious public health problem. Three of…”
Get full text

Quantum mechanical analysis of newly synthesized HIV-1 protease inhibitors: evaluation of wild-type and resistant strain binding interactions by Silva, Gabriel Vinícius Rolim, Ramos Reiniger, Klaus Augustus, de Lima Menezes, Gabriela, Bezerra, Katyanna Sales, Galvão, Douglas Soares, Saivish, Marielena Vogel, da Silva, Roosevelt Alves, Akash, Shopnil, Tayyeb, Jehad Zuhair, Oliveira, Jonas Ivan Nobre, Fulco, Umberto Laino

“…Inhibition of HIV-1 protease is a cornerstone of antiretroviral therapy. However, the notorious ability of HIV-1 to develop resistance to protease inhibitors…”
Get more information

Serine proteases in neutrophil extracellular traps exhibit anti-Respiratory Syncytial Virus activity by Lopes, Bruno Rafael Pereira, da Silva, Gabriel Soares, de Lima Menezes, Gabriela, de Oliveira, Juliana, Watanabe, Aripuanã Sakurada Aranha, Porto, Bárbara Nery, da Silva, Roosevelt Alves, Toledo, Karina Alves

“…[Display omitted] •Isolated neutrophilic serine proteases posses anti-hRSV effets.•Elastase, Proteinase 3 and Cathepsin G have in-vitro virucidal anti-hRSV…”
Get full text

Dynamic behavior of Dengue and Zika viruses NS1 protein reveals monomer-monomer interaction mechanisms and insights to rational drug design by Gonçalves, Ricardo Lemes, de Lima Menezes, Gabriela, Sussuchi, Luciane, Moreli, Marcos Lázaro, Mottin, Melina, Andrade, Carolina Horta, Pereira, Maristela, da Silva, Roosevelt Alves

“…Communicated by Ramaswamy H. Sarma…”
Get full text

Novel computational and drug design strategies for the inhibition of human T-cell leukemia virus 1-associated lymphoma by Astilbin derivatives by Akash, Shopnil, Mahmood, Sajjat, Ahamed, Rashel, Bayıl, Imren, Dev Bairagi, Rahul, Islam, Md Rezaul, Hosen, Md Eram, de Lima Menezes, Gabriela, S Almaary, Khalid, Nafidi, Hiba-Allah, Bourhia, Mohammed, Ouahmane, Lahcen

“…Human T-cell leukemia virus 1 (HTLV-1) associated lymphoma is a devastating malignancy triggered by HTLV-1 infections. We employeda comprehensive drug design…”
Get full text

Prediction of MAYV peptide antigens for immunodiagnostic tests by immunoinformatics and molecular dynamics simulations by Rodrigues, Roger Luiz, Menezes, Gabriela De Lima, Saivish, Marielena Vogel, Costa, Vivaldo Gomes Da, Pereira, Maristela, Moreli, Marcos Lázaro, Silva, Roosevelt Alves Da

“…The Mayaro virus is endemic to South America, and the possible involvement of Aedes spp. mosquitoes in its transmission is a risk factor for outbreaks of…”
Get full text

Caffeic Acid Has Antiviral Activity against Ilhéus Virus In Vitro by Saivish, Marielena Vogel, Pacca, Carolina Colombelli, da Costa, Vivaldo Gomes, de Lima Menezes, Gabriela, da Silva, Roosevelt Alves, Nebo, Liliane, da Silva, Gislaine Celestino Dutra, de Aguiar Milhim, Bruno Henrique Gonçalves, da Silva Teixeira, Igor, Henrique, Tiago, Mistrão, Natalia Franco Bueno, Hernandes, Victor Miranda, Zini, Nathalia, de Carvalho, Ana Carolina, Fontoura, Marina Alves, Rahal, Paula, Sacchetto, Lívia, Marques, Rafael Elias, Nogueira, Maurício Lacerda

“…Ilhéus virus (ILHV) is a neglected mosquito-borne flavivirus. ILHV infection may lead to Ilhéus fever, an emerging febrile disease like dengue fever with the…”
Get full text

The search for an antiviral lead molecule to combat the neglected emerging Oropouche virus by Peinado, Rafaela dos Santos, Saivish, Marielena Vogel, Menezes, Gabriela de Lima, Fulco, Umberto Laino, da Silva, Roosevelt Alves, Korostov, Karolina, Eberle, Raphael Josef, Melo, Paulo A., Nogueira, Maurício Lacerda, Pacca, Carolina Colombelli, Arni, Raghuvir Krishnaswamy, Coronado, Mônika Aparecida

“…•Oropouche virus (OROV) is the causative agent of a dengue-like febrile illness transmitted by mosquitoes with epidemic potential.•Wedelolactone (WDL) is a…”
Get full text

Acridones as promising drug candidates against Oropouche virus by Saivish, Marielena Vogel, Menezes, Gabriela de Lima, da Silva, Roosevelt Alves, de Assis, Leticia Ribeiro, Teixeira, Igor da Silva, Fulco, Umberto Laino, Avilla, Clarita Maria Secco, Eberle, Raphael Josef, Santos, Igor de Andrade, Korostov, Karolina, Webber, Mayara Lucia, da Silva, Gislaine Celestino Dutra, Nogueira, Maurício Lacerda, Jardim, Ana Carolina Gomes, Regasin, Luis Octavio, Coronado, Mônika Aparecida, Pacca, Carolina Colombelli

“…•Acridones are identified as a novel antiviral for OROV infection in vitro.•This potency is attributed to the interaction of FAC21 with the OROV…”
Get full text

Identification of potential drugs against SARS-CoV-2 non-structural protein 1 (nsp1) by de Lima Menezes, Gabriela, da Silva, Roosevelt Alves

“…Non-structural protein 1 (nsp1) is found in all Betacoronavirus genus, an important viral group that causes severe respiratory human diseases. This protein has…”
Get full text

MPO interacts with hRSV particles, contributing to the virucidal effects of NETs against clinical and laboratory hRSV isolates by da Silva Pinto, Leonardo, Junior, Ronaldo Silva Alves, Lopes, Bruno Rafael Pereira, da Silva, Gabriel Soares, de Lima Menezes, Gabriela, Moreira, Pedro, de Oliveira, Juliana, da Silva, Roosevelt Alves, Lousa, Diana, Toledo, Karina Alves

“…Human Respiratory syncytial virus (hRSV) mainly affects immunosuppressed patients requiring hospitalization. No specific treatment is financially accessible,…”
Get full text

ZIKV B-cell epitopes for immunodiagnostic tests by Kubiszeski, Janaina Rigotti, da Silva, David José Ferreira, Menezes, Gabriela de Lima, da Silva, Roosevelt Alves, Zini, Nathalia, Nogueira, Maurício Lacerda, Pena, Lindomar José, Piccoli, Julia Pinto, Cilli, Eduardo Maffud, da Silva, Joaquim Manoel, Bronzoni, Roberta Vieira de Morais

“…The use of serological tests is valuable to diagnose Zika virus (ZIKV) infection and carry out epidemiological surveillance. However, ZIKV serological tests…”
Get full text