Search Results - "de Lima Aires, André"
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Sanguinarine: an alkaloid with promising in vitro and in vivo antiparasitic activity against different developmental stages of Schistosoma mansoni and in silico pharmacokinetic properties (ADMET)
Published in Parasitology research (1987) (01-02-2024)“…The objective of the study was to evaluate the in vitro and in vivo schistosomicidal activity of sanguinarine (SA) on Schistosoma mansoni and its in silico…”
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Effects of the probiotic Bacillus cereus GM on experimental schistosomiasis mansoni
Published in Parasitology research (1987) (01-01-2024)“…Probiotics contribute to the integrity of the intestinal mucosa and preventing dysbiosis caused by opportunistic pathogens, such as intestinal helminths…”
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In Vitro Anthelminthic Activity and Ultrastructural Analysis of Barbatic Acid against Schistosomulae and Juvenile Worms of Schistosoma mansoni
Published in Chemistry & biodiversity (01-08-2023)“…Schistosomiasis affects about 260 million people worldwide and the search for new schistosomicidal compounds is urgent. In this study we evaluated the in vitro…”
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Schistosomicidal, hepatoprotective and antioxidant activities of the N-acetyl-L-cysteine and/or praziquantel in experimental acute mansonic schistosomiasis
Published in 3 Biotech (01-06-2023)“…Schistosomiasis is a tropical parasitic disease, in which the major clinical manifestation includes hepatosplenomegaly, portal hypertension, and organs…”
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Evaluation of the hydroalcoholic extract of Clarisia racemosa as an antiparasitic agent: an in vitro approach
Published in 3 Biotech (01-12-2023)“…Clarisia racemosa Ruiz & Pav is a neotropical species found in humid forests from southern Mexico to southern Brazil. There are few studies related to the…”
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Superimposing a high-fat diet on Schistosoma mansoni infection affects renin-angiotensin system components in the mouse kidney
Published in Revista da Sociedade Brasileira de Medicina Tropical (01-01-2019)“…The levels of the full-length form of the (pro)renin receptor (PRR), a component of the renin-angiotensin system (RAS), may be reduced in the membranes of…”
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Immunohistopathological changes in murine Schistosomiasis mansoni under the influence of N-acetyl-L-cysteine
Published in Parasitology research (1987) (01-10-2012)“…The main pathology associated with Schistosomiasis mansoni is granulomatous inflammation that may develop into hepatosplenic disease with fibrosis and…”
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The Natural Compound Hydrophobic Usnic Acid and Hydrophilic Potassium Usnate Derivative: Applications and Comparisons
Published in Molecules (Basel, Switzerland) (02-10-2021)“…Usnic acid is the best-studied lichen metabolite, presenting several biological activities, such as antibacterial, immunostimulating, antiviral, antifungal,…”
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Toxic, cytotoxic and genotoxic effect of plumbagin in the developmental stages of Biomphalaria glabrata (Say, 1818‐intermediate host) and cercaricidal activity against the infectious agent of schistosomiasis mansoni
Published in Pest management science (01-12-2022)“…BACKGROUND Snails of the genus Biomphalaria are intermediate hosts of Schistosoma mansoni, the main etiological agent of schistosomiasis mansoni, which affects…”
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Effect of Bauhinia monandra Kurz Leaf Preparations on Embryonic Stages and Adult Snails of Biomphalaria glabrata (Say, 1818), Schistosoma mansoni Cercariae and Toxicity in Artemia salina
Published in Molecules (Basel, Switzerland) (05-08-2022)“…snails constitute the main vector of schistosomiasis in Brazil, and Kurz, the leaves of which contain BmoLL lectin with biocidal action, is a plant widely…”
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Extract from Ascaris suum and N‐acetyl‐L‐cysteine induces an immunosuppressant effect in model of autoimmune hepatitis
Published in Parasite immunology (01-06-2021)“…Background Extract of adult Ascaris suum (ASC) worms attenuated the liver damage in experimental autoimmune hepatitis (EAH) with induction of Th2 immune…”
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Anti-Hyperuricemic, Anti-Arthritic, Hemolytic Activity and Therapeutic Safety of Glycoconjugated Triazole-Phthalimides
Published in Biomedicines (01-09-2023)“…Hyperuricemia, the metabolic alteration that leads to gout or gouty arthritis, is increasing worldwide. Glycoconjugated triazole-phthalimides show potent…”
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Dataset on schistosomiasis control using potassium usnate against Biomphalaria glabrata at different developmental stage and Schistosoma mansoni cercariae
Published in Data in brief (01-12-2018)“…This text presents complementary data corresponding to schistosomiasis mansoni׳s vector control and toxicity on Schistosoma mansoni cercariae using potassium…”
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In vitro evaluation of alkaline lignins as antiparasitic agents and their use as an excipient in the release of benznidazole
Published in International journal of biological macromolecules (15-03-2023)“…The Amazon rainforest is considered the largest tropical timber reserve in the world. The management of native forests in the Amazon is one of the most…”
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Therapeutic potential of hydantoin and thiohydantoin compounds against Schistosoma mansoni: An integrated in vitro, DNA, ultrastructural, and ADMET in silico approach
Published in Molecular and biochemical parasitology (01-12-2024)“…The study aimed to conduct in vitro biological assessments of hydantoin and thiohydantoin compounds against mature Schistosoma mansoni worms, evaluate their…”
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In vitro activity, ultrastructural analysis and in silico pharmacokinetic properties (ADMET) of thiazole compounds against adult worms of Schistosoma mansoni
Published in Acta tropica (01-09-2023)“…•Thiazole compounds have favorable bioavailability profiles.•Thiazoles promote moderate to low cytotoxicity against mammalian cells.•Thiazoles are promising…”
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New 1,3-benzodioxole derivatives: Synthesis, evaluation of in vitro schistosomicidal activity and ultrastructural analysis
Published in Chemico-biological interactions (01-03-2018)“…Schistosomiasis is considered a serious public health problem in 78 countries and territories located in Africa, Asia and America and it is estimated in more…”
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Development and evaluation of the in vitro schistosomicidal activity of solid dispersions based on 2-(-5-bromo-1-H-indole-3-yl-methylene)-N-(naphthalene-1-ylhydrazine-carbothiamide
Published in Experimental parasitology (01-01-2024)“…Among all the neglected diseases, schistosomiasis is considered the second most important parasitic infection after malaria. Praziquantel is the most widely…”
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Potential of pharmaceutical formulation based on Morinda citrifolia extract for the treatment of schistosomiasis
Published in Experimental parasitology (01-12-2023)“…Schistosomiasis is a parasitic disease that can be asymptomatic, but it can progress and cause serious damage, such as hospitalization and death. This work…”
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Toxic, cytotoxic and genotoxic effect of saline extract and fraction of Parkia pendula seeds in the developmental stages of Biomphalaria glabrata (Say 1818 – intermediate host) and cercaricide activity against the infectious agent of schistosomiasis
Published in Acta tropica (01-04-2022)“…•The saline extract and the fraction (preparations) was toxic for embryonic stages of Biomphalaria glabrata.•The preparations showed toxicity for adult snails…”
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