Search Results - "de Lima, Vladmir C"
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Malignant pleural mesothelioma: an update
Published in Jornal brasileiro de pneumologia (01-01-2021)“…Malignant mesotheliomas are rare types of cancers that affect the mesothelial surfaces, usually the pleura and peritoneum. They are associated with asbestos…”
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Lung cancer in never smokers: Tumor immunology and challenges for immunotherapy
Published in Frontiers in immunology (24-08-2022)“…Lung cancer is the second most common and the most lethal malignancy worldwide. It is estimated that lung cancer in never smokers (LCINS) accounts for 10-25%…”
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Fusion Cell Markers in Circulating Tumor Cells from Patients with High-Grade Ovarian Serous Carcinoma
Published in International journal of molecular sciences (24-11-2022)“…Cancer is primarily a disease in which late diagnosis is linked to poor prognosis, and unfortunately, detection and management are still challenging…”
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The impact of sociodemographic factors and health insurance coverage in the diagnosis and clinicopathological characteristics of breast cancer in Brazil: AMAZONA III study (GBECAM 0115)
Published in Breast cancer research and treatment (01-10-2020)“…Purpose In Brazil, the available cancer registries are deficient in number and quality and, hence, little information is known regarding sociodemographic,…”
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A high CD8 to FOXP3 ratio in the tumor stroma and expression of PTEN in tumor cells are associated with improved survival in non-metastatic triple-negative breast carcinoma
Published in BMC cancer (06-08-2021)“…Background Triple-negative mammary carcinoma (TNBC) is an aggressive breast cancer subtype associated with dismal prognosis. The interaction between the immune…”
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STK11 and KEAP1 mutations in non-small cell lung cancer patients: Descriptive analysis and prognostic value among Hispanics (STRIKE registry-CLICaP)
Published in Lung cancer (Amsterdam, Netherlands) (01-08-2022)“…•STK11 and KEAP1 have been described as poor prognostic factors in patients treated with immune checkpoint inhibitors (ICIs).•This is the larger study to…”
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Assessing Oncologists’ Attitudes Concerning Comprehensive Genomic Profiling in Stage IV Lung Adenocarcinoma in Brazil
Published in JTO clinical and research reports (01-10-2022)“…Advances in comprehensive genomic profiling (CGP) of lung adenocarcinomas (LUADs) led to personalized treatment for patients. This study evaluated medical…”
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8
Gas chromatography-mass spectrometry untargeted profiling of non-Hodgkin’s lymphoma urinary metabolite markers
Published in Analytical and bioanalytical chemistry (01-11-2020)“…Non-Hodgkin’s lymphoma (NHL) is a cancer of the lymphatic system where the lymphoid and hematopoietic tissues are infiltrated by malignant neoplasms of B, T,…”
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Systemic immune mediators reflect tumour‐infiltrating lymphocyte intensity and predict therapeutic response in triple‐negative breast cancer
Published in Immunology (01-06-2023)“…Triple‐negative breast cancer (TNBC) is an aggressive form of breast cancer (BC). Neoadjuvant chemotherapy has proven efficacy in its treatment, and a…”
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10
Gene expression profiles (GEPs) of immuno-oncologic pathways as predictors of response to checkpoint inhibitors in advanced NSCLC
Published in Translational oncology (01-01-2024)“…BACKGROUNDImmune checkpoint inhibitors (ICIs) revolutionized non-small-cell lung cancer (NSCLC) treatment. However, improving patients' selection for this…”
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Mutational Portrait of Lung Adenocarcinoma in Brazilian Patients: Past, Present, and Future of Molecular Profiling in the Clinic
Published in Frontiers in oncology (02-07-2020)“…Objectives: Approximately 60% of lung adenocarcinomas (LAs) carry mutations that can guide treatment with tyrosine-kinase inhibitors (TKI) and other targeted…”
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Low PTEN expression is associated with worse overall survival in head and neck squamous cell carcinoma patients treated with chemotherapy and cetuximab
Published in International journal of clinical oncology (01-04-2015)“…Background Platinum-based chemotherapy associated with cetuximab is the first-line treatment for inoperable recurrence or metastatic head and neck squamous…”
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13
NDRG4 promoter hypermethylation is a mechanistic biomarker associated with metastatic progression in breast cancer patients
Published in NPJ breast cancer (05-04-2019)“…The risk of developing metastatic disease in breast cancer patients is traditionally predictable based on the number of positive axillary lymph nodes,…”
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Characteristics and long‐term outcomes of advanced pleural mesothelioma in Latin America (MeSO‐CLICaP)
Published in Thoracic cancer (01-03-2019)“…Background Malignant pleural mesothelioma (MPM) is an aggressive tumor, associated with poor prognosis. There is a lack of information about the clinical and…”
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Genetic Ancestry Affects Somatic Alterations in Lung Cancers
Published in Cancer discovery (01-06-2021)Get more information
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16
Prognostic impact of MUM1 expression by immunohistochemistry on primary mediastinal large B-cell lymphoma
Published in Leukemia & lymphoma (01-08-2011)“…Diffuse large B-cell lymphoma can be classified into two prognostically distinct subgroups with germinal center B-cell-like (CG) and activated B-cell-like…”
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High Prevalence of EGFR Mutations in Lung Adenocarcinomas From Brazilian Patients Harboring the TP53 p.R337H Variant
Published in Clinical lung cancer (01-03-2020)Get full text
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Loss of prion protein is associated with the development of insulin resistance and obesity
Published in Biochemical journal (01-09-2017)“…Prion protein (PrP ) was initially described due to its involvement in transmissible spongiform encephalopathies. It was subsequently demonstrated to be a cell…”
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Genomic Landscape of Primary Resistance to Osimertinib Among Hispanic Patients with EGFR-Mutant Non-Small Cell Lung Cancer (NSCLC): Results of an Observational Longitudinal Cohort Study
Published in Targeted oncology (01-05-2023)“…Background Epidermal growth factor receptor ( EGFR) mutations ( EGFR m) represent one of the most common genomic alterations identified among patients with…”
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Real-World Prevalence of PD-L1 Expression Among Tumor Samples From Patients With Non–Small-Cell Lung Cancer
Published in Clinical lung cancer (01-11-2020)“…We analyzed the prevalence of non–small-cell lung cancer (NSCLC) with a programmed cell death ligand 1 (PD-L1) tumor proportion score (TPS) of ≥ 50% and…”
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