Search Results - "de Leon, Alexander R"

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  1. 1

    Binocular sensitivity and specificity of screening tests in cross‐sectional diagnostic studies of paired organs by Perera, Yamuni, Ren, Mingchen, Punzalan, Joyce Raymond B., Rudnisky, Christopher J., de Leon, Alexander R.

    Published in Statistics in medicine (20-05-2017)
    “…We introduce new binocular accuracy measures as alternatives to conventional marginal measures that can be used to evaluate screening tests in diagnostic…”
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    Journal Article
  2. 2

    Performance of variable selection methods using stability-based selection by Lu, Danny, Weljie, Aalim, de Leon, Alexander R, McConnell, Yarrow, Bathe, Oliver F, Kopciuk, Karen

    Published in BMC research notes (04-04-2017)
    “…Variable selection is frequently carried out during the analysis of many types of high-dimensional data, including those in metabolomics. This study compared…”
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    Journal Article
  3. 3

    A two‐level copula joint model for joint analysis of longitudinal and competing risks data by Lu, Xiaoming, Chekouo, Thierry, Shen, Hua, Leon, Alexander R.

    Published in Statistics in medicine (30-05-2023)
    “…In this article, we propose a two‐level copula joint model to analyze clinical data with multiple disparate continuous longitudinal outcomes and multiple…”
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    Journal Article
  4. 4

    General mixed-data model: Extension of general location and grouped continuous models by De LEON, Alexander R., Carriègre, K. C.

    Published in Canadian journal of statistics (01-12-2007)
    “…The authors propose a general model for the joint distribution of nominal, ordinal and continuous variables. Their work is motivated by the treatment of…”
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    Journal Article
  5. 5

    Gaussian Copula Mixed Models for Clustered Mixed Outcomes, With Application in Developmental Toxicology by Wu, Beilei, de Leon, Alexander R

    “…This paper is concerned with the analysis of clustered data from developmental toxicity studies with mixed responses, i.e., where each member of the cluster…”
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  6. 6

    Joint estimation of multiple disease-specific sensitivities and specificities via crossed random effects models for correlated reader-based diagnostic data: application of data cloning by Withanage, Niroshan, de Leon, Alexander R., Rudnisky, Christopher J.

    Published in Statistics in medicine (20-12-2015)
    “…We present a model for describing correlated binocular data from reader‐based diagnostic studies, where the same group of readers evaluates the presence or…”
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  8. 8

    High-resolution stereoscopic digital fundus photography versus contact lens biomicroscopy for the detection of clinically significant macular edema by Rudnisky, Christopher J, Hinz, Brad J, Tennant, Matthew T S, de Leon, Alexander R, Greve, Mark D J

    Published in Ophthalmology (Rochester, Minn.) (01-02-2002)
    “…The purpose of this study was to compare high-resolution stereoscopic digital photography to contact lens biomicroscopy (CLBM) for the diagnosis of clinically…”
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    Journal Article
  9. 9

    Joint Estimation of Diagnostic Accuracy Measures for Paired Organs - Application in Ophthalmology by de Leon, Alexander R., Soo, Andrea, Bonzo, Daniel C., Rudnisky, Christopher J.

    Published in Biometrical journal (01-10-2009)
    “…Diagnostic studies in ophthalmology frequently involve binocular data where pairs of eyes are evaluated, through some diagnostic procedure, for the presence of…”
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  10. 10

    Benefits of stereopsis when identifying clinically significant macular edema via teleophthalmology by Rudnisky, Christopher J., Tennant, Matthew T.S., de Leon, Alexander R., Hinz, Bradley J., Greve, Mark D.J.

    Published in Canadian journal of ophthalmology (01-12-2006)
    “…Background: The need to incorporate stereopsis into a teleophthalmology system is controversial. Detection of hard exudate in the macula is suggested by some…”
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    Journal Article
  11. 11

    Gaussian copula mixed models for clustered mixed outcomes, with application in developmental toxicology by Wu, Beilei, de Leon, Alexander R

    “…This paper is concerned with the analysis of clustered data from developmental toxicity studies with mixed responses, i.e., where each member of the cluster…”
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    Journal Article
  12. 12
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    Letter to the Editor by Wu, Beilei, de Leon, Alexander R.

    Published in Biometrical journal (01-09-2013)
    “…Regarding Paper “Sample size determination in clinical trials with multiple co‐primary endpoints including mixed continuous and binary variables” by T. Sozu ,…”
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    Journal Article
  14. 14

    Letter to the Editor by Wu, Beilei, de Leon, Alexander R.

    Published in Biometrical journal (01-09-2013)
    “…Regarding Paper “Sample size determination in clinical trials with multiple co‐primary endpoints including mixed continuous and binary variables” by T. Sozu,…”
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    Journal Article
  15. 15

    Letter to the Editor by Wu, Beilei, de Leon, Alexander R

    Published in Biometrical journal (01-09-2013)
    “…Regarding Paper "Sample size determination in clinical trials with multiple co-primary endpoints including mixed continuous and binary variables" by T. Sozu,…”
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    Journal Article
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