Search Results - "de Leeuw, Lidewij R."

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    LXR Agonist T0901317′s Hepatic Impact Overrules Its Atheroprotective Action in Macrophages, Driving Early Atherogenesis in Chow-Diet-Fed Male Apolipoprotein E Knockout Mice by Hoekstra, Menno, de Jong, Laura M, van der Geest, Rick, de Leeuw, Lidewij R, Krisnamurthi, Rani, Geerling, Janine J, Van Eck, Miranda

    Published in Biomolecules (Basel, Switzerland) (01-04-2024)
    “…Preclinical studies regarding the potential of liver X receptor (LXR) agonists to inhibit macrophage foam cell formation and the development of atherosclerotic…”
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    Journal Article
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    Inhibition of PRMT3 activity reduces hepatic steatosis without altering atherosclerosis susceptibility in apoE knockout mice by Hoekstra, Menno, Nahon, Joya E., de Jong, Laura M., Kröner, Mara J., de Leeuw, Lidewij R., Van Eck, Miranda

    “…The nuclear receptor liver X receptor (LXR) impacts on cholesterol metabolism as well as hepatic lipogenesis via transcriptional regulation. It is proposed…”
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    Journal Article
  4. 4

    Abca1 deficiency protects the heart against myocardial infarction-induced injury by Louwe, Mieke C, Lammers, Bart, Frias, Miguel A, Foks, Amanda C, de Leeuw, Lidewij R, Hildebrand, Reeni B, Kuiper, Johan, Smit, Johannes W.A, Van Berkel, Theo J.C, James, Richard W, Geerling, Janine J, Rensen, Patrick C.N, Van Eck, Miranda

    Published in Atherosclerosis (01-08-2016)
    “…Abstract Background and aims We explored the role of ATP-binding cassette transporter A1 (Abca1), in post-myocardial infarction (MI) cardiac injury. Methods In…”
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    Journal Article
  5. 5

    LXR Agonist T0901317's Hepatic Impact Overrules Its Atheroprotective Action in Macrophages, Driving Early Atherogenesis in Chow-Diet-Fed Male Apolipoprotein E Knockout Mice by Hoekstra, Menno, de Jong, Laura M, van der Geest, Rick, de Leeuw, Lidewij R, Krisnamurthi, Rani, Geerling, Janine J, Van Eck, Miranda

    Published in Biomolecules (Basel, Switzerland) (02-04-2024)
    “…Preclinical studies regarding the potential of liver X receptor (LXR) agonists to inhibit macrophage foam cell formation and the development of atherosclerotic…”
    Get full text
    Journal Article