Search Results - "de León, Mario Bermudez"
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5-Aza-2'-Deoxycytidine and Valproic Acid in Combination with CHIR99021 and A83-01 Induce Pluripotency Genes Expression in Human Adult Somatic Cells
Published in Molecules (Basel, Switzerland) (29-03-2021)“…A generation of induced pluripotent stem cells (iPSC) by ectopic expression of OCT4, SOX2, KLF4, and c-MYC has established promising opportunities for stem…”
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Isotretinoin and Thalidomide Down-Regulate c-MYC Gene Expression and Modify Proteins Associated with Cancer in Hepatic Cells
Published in Molecules (Basel, Switzerland) (22-09-2021)“…Hepatocellular carcinoma (HCC) is the most common form of liver cancer. The number of cases is increasing and the trend for the next few years is not…”
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Transcription factors YY1, Sp1 and Sp3 modulate dystrophin Dp71 gene expression in hepatic cells
Published in Biochemical journal (01-07-2016)“…Dystrophin Dp71, the smallest product encoded by the Duchenne muscular dystrophy gene, is ubiquitously expressed in all non-muscle cells. Although Dp71 is…”
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Side Effects of COVID-19 Vaccines in Pregnant and Lactating Mexican Women and Breastfed Infants: A Survey-Based Study
Published in Vaccines (Basel) (25-07-2023)“…COVID-19 vaccines’ safety has been extensively studied; however, further analysis is required in pregnant women, nursing mothers, and breastfed infants. Our…”
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ESX-3 secretion system in Mycobacterium: An overview
Published in Biochimie (01-01-2024)“…Mycobacteria are microorganisms distributed in the environment worldwide, and some of them, such as Mycobacterium tuberculosis or M. leprae, are pathogenic…”
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Changes in gene expression induced by polycyclic aromatic hydrocarbons in the human cell lines HepG2 and A549
Published in Toxicology in vitro (01-03-2008)“…Polycyclic aromatic hydrocarbons (PAH) are the main components of emissions generated by coke oven factories and many of these chemicals are carcinogenic. The…”
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Mechanistic Insights about Sorafenib-, Valproic Acid- and Metformin-Induced Cell Death in Hepatocellular Carcinoma
Published in International journal of molecular sciences (01-02-2024)“…Hepatocellular carcinoma (HCC) is among the main causes of death by cancer worldwide, representing about 80-90% of all liver cancers. Treatments available for…”
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Cardiovascular Risk Factors as Predictors of Nutritional Status in Older Mexican Adults
Published in Nutrients (12-08-2024)“…Aging is commonly accompanied by increased cardiovascular risk and diet plays a crucial role in health condition. The aim of this study was to determine…”
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Suspension culture improves iPSC expansion and pluripotency phenotype
Published in Stem cell research & therapy (06-06-2023)“…Induced pluripotent stem cells (iPSCs) offer potential to revolutionize regenerative medicine as a renewable source for islets, dopaminergic neurons, retinal…”
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10
Prenatal indole-3-carbinol administration activates aryl hydrocarbon receptor-responsive genes and attenuates lung injury in a bronchopulmonary dysplasia model
Published in Experimental biology and medicine (Maywood, N.J.) (01-03-2021)“…Hyperoxia−hypoxia exposure is a proposed cause of alveolar developmental arrest in bronchopulmonary dysplasia in preterm infants, where mitochondrial reactive…”
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Pharmacogenetics of amfepramone in healthy Mexican subjects reveals potential markers for tailoring pharmacotherapy of obesity: results of a randomised trial
Published in Scientific reports (28-11-2019)“…Amfepramone (AFP) is an appetite-suppressant drug used in the treatment of obesity. Nonetheless, studies on interindividual pharmacokinetic variability and its…”
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Selenite Downregulates STAT3 Expression and Provokes Lymphocytosis in the Liver of Chronically Exposed Syrian Golden Hamsters
Published in Molecules (Basel, Switzerland) (16-09-2021)“…Arsenic is considered a worldwide pollutant that can be present in drinking water. Arsenic exposure is associated with various diseases, including cancer…”
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ABC-GOALScl score predicts admission to the intensive care unit and mortality of COVID-19 patients over 60 years of age
Published in BMC geriatrics (10-03-2023)“…One of the risk factors for getting seriously ill from COVID-19 and reaching high mortality rates is older age. Older age is also associated with…”
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Extension and Severity of Self-Reported Side Effects of Seven COVID-19 Vaccines in Mexican Population
Published in Frontiers in public health (14-03-2022)“…A few studies examined the comparative side effects of Coronavirus Disease-19 (COVID-19) vaccines. We compared the extension and severity of self-reported side…”
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Cell-type dependent regulation of pluripotency and chromatin remodeling genes by hydralazine
Published in Stem cell research & therapy (16-03-2023)“…The generation of induced pluripotent stem cells has opened the field of study for stem cell research, disease modeling and drug development. However, the…”
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Paxlovid™ reduces the incidence of pneumonia, hospitalization, and death in a cohort of COVID-19 patients from northeast Mexico
Published in Journal of infection and public health (01-07-2024)“…Information on Paxlovid™ effectiveness must be monitored and updated in real world scenarios. Our research question was what is the effectiveness of Paxlovid™…”
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LipF increases rifampicin and streptomycin sensitivity in a Mycobacterium tuberculosis surrogate
Published in BMC microbiology (25-05-2020)“…Mortality due to tuberculosis (TB) has increased due to the development of drug resistance, the mechanisms of which have not been fully elucidated. Our…”
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Two New Dihydrosphingosine Analogs Against Mycobacterium tuberculosis Affect gltA1, lprQ, and rpsO Expression
Published in Frontiers in microbiology (03-11-2021)“…The emergence of multidrug-resistant (MDR) Mycobacterium tuberculosis strains threaten the control of tuberculosis. New antitubercular dihydrosphingosine…”
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Differential expression of putative drug resistance genes in Mycobacterium tuberculosis clinical isolates
Published in FEMS microbiology letters (01-12-2015)“…Understanding drug resistance in Mycobacterium tuberculosis requires an integrated analysis of strain lineages, mutations and gene expression. Previously, we…”
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Arsenic Induces DNA Damage in Environmentally Exposed Mexican Children and Adults. Influence of GSTO1 and AS3MT Polymorphisms
Published in Toxicological sciences (01-09-2010)“…Inorganic arsenic (i-As) is an environmental carcinogen to which millions of people are chronically exposed mainly via drinking water. In this study, we used…”
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