Search Results - "de Lara, Catherine"

T cell assays differentiate clinical and subclinical SARS-CoV-2 infections from cross-reactive antiviral responses by Ogbe, Ane, Kronsteiner, Barbara, Skelly, Donal T., Pace, Matthew, Brown, Anthony, Adland, Emily, Adair, Kareena, Akhter, Hossain Delowar, Ali, Mohammad, Ali, Serat-E, Angyal, Adrienn, Ansari, M. Azim, Arancibia-Cárcamo, Carolina V., Brown, Helen, Chinnakannan, Senthil, Conlon, Christopher, de Lara, Catherine, de Silva, Thushan, Dold, Christina, Dong, Tao, Donnison, Timothy, Eyre, David, Flaxman, Amy, Fletcher, Helen, Gardner, Joshua, Grist, James T., Hackstein, Carl-Philipp, Jaruthamsophon, Kanoot, Jeffery, Katie, Lambe, Teresa, Lee, Lian, Li, Wenqin, Lim, Nicholas, Matthews, Philippa C., Mentzer, Alexander J., Moore, Shona C., Naisbitt, Dean J., Ogese, Monday, Ogg, Graham, Openshaw, Peter, Pirmohamed, Munir, Pollard, Andrew J., Ramamurthy, Narayan, Rongkard, Patpong, Rowland-Jones, Sarah, Sampson, Oliver, Screaton, Gavin, Sette, Alessandro, Stafford, Lizzie, Thompson, Craig, Thomson, Paul J., Thwaites, Ryan, Vieira, Vinicius, Weiskopf, Daniela, Zacharopoulou, Panagiota, Turtle, Lance, Klenerman, Paul, Goulder, Philip, Frater, John, Barnes, Eleanor, Dunachie, Susanna

“…Identification of protective T cell responses against SARS-CoV-2 requires distinguishing people infected with SARS-CoV-2 from those with cross-reactive…”
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Illumina and Nanopore methods for whole genome sequencing of hepatitis B virus (HBV) by McNaughton, Anna L., Roberts, Hannah E., Bonsall, David, de Cesare, Mariateresa, Mokaya, Jolynne, Lumley, Sheila F., Golubchik, Tanya, Piazza, Paolo, Martin, Jacqueline B., de Lara, Catherine, Brown, Anthony, Ansari, M. Azim, Bowden, Rory, Barnes, Eleanor, Matthews, Philippa C.

“…Advancing interventions to tackle the huge global burden of hepatitis B virus (HBV) infection depends on improved insights into virus epidemiology,…”
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Adenoviral Vector Vaccination Induces a Conserved Program of CD8+ T Cell Memory Differentiation in Mouse and Man by Bolinger, Beatrice, Sims, Stuart, Swadling, Leo, O’Hara, Geraldine, de Lara, Catherine, Baban, Dilair, Saghal, Natasha, Lee, Lian Ni, Marchi, Emanuele, Davis, Mark, Newell, Evan, Capone, Stefania, Folgori, Antonella, Barnes, Ellie, Klenerman, Paul

“…Following exposure to vaccines, antigen-specific CD8+ T cell responses develop as long-term memory pools. Vaccine strategies based on adenoviral vectors, e.g.,…”
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In vivo T lymphocyte dynamics in humans and the impact of human T-lymphotropic virus 1 infection by Asquith, Becca, Zhang, Yan, Mosley, Angelina J, de Lara, Catherine M, Wallace, Diana L, Worth, Andrew, Kaftantzi, Lambrini, Meekings, Kiran, Griffin, George E, Tanaka, Yuetsu, Tough, David F, Beverley, Peter C, Taylor, Graham P, Macallan, Derek C, Bangham, Charles R.M

“…Human T-lymphotropic virus type 1 (HTLV-1) is a persistent CD4⁺ T-lymphotropic retrovirus. Most HTLV-1-infected individuals remain asymptomatic, but a…”
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MAIT cells are activated during human viral infections by van Wilgenburg, Bonnie, Scherwitzl, Iris, Hutchinson, Edward C., Leng, Tianqi, Kurioka, Ayako, Kulicke, Corinna, de Lara, Catherine, Cole, Suzanne, Vasanawathana, Sirijitt, Limpitikul, Wannee, Malasit, Prida, Young, Duncan, Denney, Laura, Moore, Michael D., Fabris, Paolo, Giordani, Maria Teresa, Oo, Ye Htun, Laidlaw, Stephen M., Dustin, Lynn B., Ho, Ling-Pei, Thompson, Fiona M., Ramamurthy, Narayan, Mongkolsapaya, Juthathip, Willberg, Christian B., Screaton, Gavin R., Klenerman, Paul

“…Mucosal-associated invariant T (MAIT) cells are abundant in humans and recognize bacterial ligands. Here, we demonstrate that MAIT cells are also activated…”
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Chimpanzee adenovirus- and MVA-vectored respiratory syncytial virus vaccine is safe and immunogenic in adults by Green, Christopher A, Scarselli, Elisa, Sande, Charles J, Thompson, Amber J, de Lara, Catherine M, Taylor, Kathryn S, Haworth, Kathryn, Del Sorbo, Mariarosaria, Angus, Brian, Siani, Loredana, Di Marco, Stefania, Traboni, Cinzia, Folgori, Antonella, Colloca, Stefano, Capone, Stefania, Vitelli, Alessandra, Cortese, Riccardo, Klenerman, Paul, Nicosia, Alfredo, Pollard, Andrew J

“…Respiratory syncytial virus (RSV) causes respiratory infection in annual epidemics, with infants and the elderly at particular risk of developing severe…”
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Novel genetically-modified chimpanzee adenovirus and MVA-vectored respiratory syncytial virus vaccine safely boosts humoral and cellular immunity in healthy older adults by Green, Christopher A., Sande, Charles J., Scarselli, Elisa, Capone, Stefania, Vitelli, Alessandra, Nicosia, Alfredo, Silva-Reyes, Laura, Thompson, Amber J., de Lara, Catherine M., Taylor, Kathryn S., Haworth, Kathryn, Hutchings, Claire L., Cargill, Tamsin, Angus, Brian, Klenerman, Paul, Pollard, Andrew J.

“…•There is no licensed vaccine to prevent severe disease caused by respiratory syncytial virus (RSV) infection.•RSV is a major cause of hospitalisation and…”
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In vivo kinetics of human natural killer cells: the effects of ageing and acute and chronic viral infection by Zhang, Yan, Wallace, Diana L, de Lara, Catherine M, Ghattas, Hala, Asquith, Becca, Worth, Andrew, Griffin, George E, Taylor, Graham P, Tough, David F, Beverley, Peter C.L, Macallan, Derek C

“…Human natural killer (NK) cells form a circulating population in a state of dynamic homeostasis. We investigated NK cell homeostasis by labelling dividing…”
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Adenoviral vaccine induction of CD8+ T cell memory inflation: Impact of co-infection and infection order by Lee, Lian N, Bolinger, Beatrice, Banki, Zoltan, de Lara, Catherine, Highton, Andrew J, Colston, Julia M, Hutchings, Claire, Klenerman, Paul

“…The efficacies of many new T cell vaccines rely on generating large populations of long-lived pathogen-specific effector memory CD8 T cells. However, it is now…”
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Human cytomegalovirus-specific CD8⁺ T-cell expansions contain long-lived cells that retain functional capacity in both young and elderly subjects by Wallace, Diana L, Masters, Joanne E, De Lara, Catherine M, Henson, Sian M, Worth, Andrew, Zhang, Yan, Kumar, Shikha R, Beverley, Peter C, Akbar, Arne N, Macallan, Derek C

“…The immune response to human cytomegalovirus (HCMV) infection is characterized by the accumulation of HCMV-specific CD8⁺ T cells, particularly in the elderly;…”
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CXCR6 Is a Marker for Protective Antigen-Specific Cells in the Lungs after Intranasal Immunization against Mycobacterium tuberculosis by Lee, Lian Ni, Ronan, Edward O, de Lara, Catherine, Franken, Kees L M C, Ottenhoff, Tom H M, Tchilian, Elma Z, Beverley, Peter C L

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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B-cell kinetics in humans: rapid turnover of peripheral blood memory cells by Macallan, Derek C., Wallace, Diana L., Zhang, Yan, Ghattas, Hala, Asquith, Becca, de Lara, Catherine, Worth, Andrew, Panayiotakopoulos, George, Griffin, George E., Tough, David F., Beverley, Peter C.L.

“…Information about the kinetic behavior and lifespan of lymphocytes is crucial to understanding the mechanisms that regulate processes such as immunologic…”
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Accelerated in vivo proliferation of memory phenotype CD4+ T-cells in human HIV-1 infection irrespective of viral chemokine co-receptor tropism by Zhang, Yan, de Lara, Catherine, Worth, Andrew, Hegedus, Andrea, Laamanen, Karoliina, Beverley, Peter, Macallan, Derek

“…CD4(+) T-cell loss is the hallmark of HIV-1 infection. CD4 counts fall more rapidly in advanced disease when CCR5-tropic viral strains tend to be replaced by…”
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Simultaneous immunization against tuberculosis by Tchilian, Elma Z, Ronan, Edward O, de Lara, Catherine, Lee, Lian Ni, Franken, Kees L M C, Vordermeier, Martin H, Ottenhoff, Tom H M, Beverley, Peter C L

“…BCG, the only licensed vaccine against tuberculosis, provides some protection against disseminated disease in infants but has little effect on prevention of…”
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Single-cell transcriptome analysis of CD8 + T-cell memory inflation by Highton, Andrew J, Zinser, Madeleine E, Lee, Lian Ni, Hutchings, Claire L, De Lara, Catherine, Phetsouphanh, Chansavath, Willberg, Chris B, Gordon, Claire L, Klenerman, Paul, Marchi, Emanuele

“…: Persistent viruses such as murine cytomegalovirus (MCMV) and adenovirus-based vaccines induce strong, sustained CD8 T-cell responses, described as memory…”
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CD161++CD8+ T cells, including the MAIT cell subset, are specifically activated by IL‐12+IL‐18 in a TCR‐independent manner by Ussher, James E., Bilton, Matthew, Attwod, Emma, Shadwell, Jonathan, Richardson, Rachel, Lara, Catherine, Mettke, Elisabeth, Kurioka, Ayako, Hansen, Ted H., Klenerman, Paul, Willberg, Christian B.

“…CD161++CD8+ T cells represent a novel subset that is dominated in adult peripheral blood by mucosal‐associated invariant T (MAIT) cells, as defined by the…”
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Immunogenicity of standard and extended dosing intervals of BNT162b2 mRNA vaccine by Payne, Rebecca P., Austin, James A., Skelly, Donal T., Meardon, Naomi, Faustini, Sian, Al-Taei, Saly, Moore, Shona C., Hering, Luisa M., Angyal, Adrienn, Brown, Rebecca, Nicols, Alexander R., Gillson, Natalie, Dobson, Susan L., Amini, Ali, Supasa, Piyada, Cross, Andrew, Bridges-Webb, Alice, Linder, Aline, Altmann, Thomas, Whitham, Rachel, Phillips, Eloise, Hargreaves, Alexander, Shields, Adrian, Foulkes, Sarah, Johnson, Sile, Wootton, Daniel G., Conlon, Christopher P., Matthews, Philippa C., Frater, John, Deeks, Alexandra S., Pollard, Andrew J., Brown, Anthony, Rowland-Jones, Sarah L., Mongkolsapaya, Juthathip, Hopkins, Susan, Dold, Christina, Richter, Alex, Carroll, Miles, Screaton, Gavin, de Silva, Thushan I., Turtle, Lance, Klenerman, Paul, Dunachie, Susanna, Abuelgasim, Hibatullah, Adland, Emily, Adlou, Syed, Akther, Hossain Delowar, Ansari, M. Azim, Arancibia-Cárcamo, Carolina V., Bayley, Martin, Brown, Helen, Chand, Meera, Chawla, Anu, Chinnakannan, Senthil, Cutteridge, Joseph, de Lara, Catherine, Denly, Lucy, Diffey, Ben, Dimitriadis, Stavros, Drake, Thomas M., Donnison, Timothy, Dupont, Maeva, Gardiner, Siobhan, Gilbert-Jarmillo, Javier, Goulder, Philip, Hackstein, Carl-Philipp, Hambleton, Sophie, Haniffa, Muzlifah, Haworth, Jenny, Holmes, Jennifer, Jämsén, Anni, Johnson, Sile, Jones, Chris, Kelly, Sinead, Kirk, Rosemary, Knight, Michael L., Lawrie, Allan, Lee, Lian, Lett, Lauren, Lim, Nicholas, Mentzer, Alexander J., O’Donnell, Denise, Payne, Brendan A.I., Provine, Nicholas, Robinson, Nichola, Romaniuk, Leigh, Simmons, Beatrice, Spegarova, Jarmila S., Stephenson, Emily, Subramaniam, Kris, Travis, Simon, Tucker, Stephanie, Watson, Adam, Watson, Lisa, Weeks, Esme, Wilson, Robert, Wood, Steven, Wright, Rachel, Xiao, Huiyuan, Zawia, Amira A.T.

“…Extension of the interval between vaccine doses for the BNT162b2 mRNA vaccine was introduced in the United Kingdom to accelerate population coverage with a…”
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SAT-394 HBV genotyping: grasping a new window of opportunity? by Delphin, Marion, Li, Ka Chun, Waddilove, Elizabeth, Tan, Cedric, Martin, Jacqueline, De Lara, Catherine, Barnes, Eleanor, Lourenco, Jose, Matthews, Philippa C

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First-in-Human Randomized Study to Assess the Safety and Immunogenicity of an Investigational Respiratory Syncytial Virus (RSV) Vaccine Based on Chimpanzee-Adenovirus-155 Viral Vector-Expressing RSV Fusion, Nucleocapsid, and Antitermination Viral Proteins in Healthy Adults by Cicconi, Paola, Jones, Claire, Sarkar, Esha, Silva-Reyes, Laura, Klenerman, Paul, de Lara, Catherine, Hutchings, Claire, Moris, Philippe, Janssens, Michel, Fissette, Laurence A, Picciolato, Marta, Leach, Amanda, Gonzalez-Lopez, Antonio, Dieussaert, Ilse, Snape, Matthew D

“…Respiratory syncytial virus (RSV) disease is a major cause of infant morbidity and mortality. This Phase I, randomized, observer-blind, placebo- and…”
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SAT-404 The Lipidome in phenotyping hepatitis B infection (‘LiPHe-B’): preliminary results from our pilot study by Delphin, Marion, Palma-Duran, Susana, Santos, Mariana Silva dos, Martyn, Emily, Waddilove, Elizabeth, Wall, Emma, Maponga, Tongai Gibson, Martin, Jacqueline, De Lara, Catherine, Klenerman, Paul, Barnes, Eleanor, Macrae, James, Matthews, Philippa C

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