Search Results - "de Lange, Kim"

Evaluation of a seven gene mutational profile as a prognostic factor in a population-based study of clear cell renal cell carcinoma by van de Pol, Jeroen A. A., Ferronika, Paranita, Westers, Helga, van Engeland, Manon, Terpstra, Martijn M., Smits, Kim M., de Lange, Kim, van den Brandt, Piet A., Sijmons, Rolf H., Schouten, Leo J., Kok, Klaas

“…In this study, we investigate the influence of the seven genes ( VHL, PBRM1, SETD2, BAP1, KDM5C, MTOR and TP53 ) most frequently mutated in clear cell renal…”
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Gene expression profiling of epithelium-associated FcRL4+ B cells in primary Sjögren's syndrome reveals a pathogenic signature by Verstappen, Gwenny M., Ice, John A., Bootsma, Hendrika, Pringle, Sarah, Haacke, Erlin A., de Lange, Kim, van der Vries, Gerben B., Hickey, Peter, Vissink, Arjan, Spijkervet, Frederik K.L., Lessard, Christopher J., Kroese, Frans G.M.

“…In primary Sjögren's syndrome (pSS), FcRL4+ B cells are present in inflamed salivary gland tissue, within or in close proximity to ductal epithelium. FcRL4 is…”
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Detection of Fusion Genes to Determine Minimal Residual Disease in Leukemia Using Next-Generation Sequencing by de Boer, Eddy N, Johansson, Lennart F, de Lange, Kim, Bosga-Brouwer, Anneke G, van den Berg, Eva, Sikkema-Raddatz, Birgit, van Diemen, Cleo C

“…Abstract Background Measuring minimal residual disease (MRD), the persistence of leukemic cells after treatment, is important for monitoring leukemia…”
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Targeted RNA-Sequencing Enables Detection of Relevant Translocations and Single Nucleotide Variants and Provides a Method for Classification of Hematological Malignancies-RANKING by de Lange, Kim, de Boer, Eddy N, Bosga, Anneke, Alimohamed, Mohamed Z, Johansson, Lennart F, Mulder, André B, Vellenga, Edo, van Diemen, Cleo C, Deelen, Patrick, van den Berg, Eva, Sikkema-Raddatz, Birgit

“…Patients with hematological malignancies (HMs) carry a wide range of chromosomal and molecular abnormalities that impact their prognosis and treatment. Since…”
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Mutation patterns in small cell and non-small cell lung cancer patients suggest a different level of heterogeneity between primary and metastatic tumors by Saber, Ali, Hiltermann, T Jeroen N, Kok, Klaas, Terpstra, M Martijn, de Lange, Kim, Timens, Wim, Groen, Harry J M, van den Berg, Anke

“…Several studies have shown heterogeneity in lung cancer, with parallel existence of multiple subclones characterized by their own specific mutational…”
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Mutational heterogeneity between different regional tumour grades of clear cell renal cell carcinoma by Ferronika, Paranita, Kats-Ugurlu, Gursah, Haryana, Sofia M., Utoro, Totok, Rinonce, Hanggoro Tri, Danarto, Raden, de Lange, Kim, Terpstra, Martijn M., Sijmons, Rolf H., Westers, Helga, Kok, Klaas

“…Only a limited number of studies have explored the possible associations between tumour grade and mutated genes in clear cell renal cell carcinoma (ccRCC), and…”
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Running‐wheel activity delays mitochondrial respiratory flux decline in aging mouse muscle via a post‐transcriptional mechanism by Stolle, Sarah, Ciapaite, Jolita, Reijne, Aaffien C., Talarovicova, Alzbeta, Wolters, Justina C., Aguirre‐Gamboa, Raúl, Vlies, Pieter, Lange, Kim, Neerincx, Pieter B., Vries, Gerben, Deelen, Patrick, Swertz, Morris A., Li, Yang, Bischoff, Rainer, Permentier, Hjalmar P., Horvatovitch, Peter L., Groen, Albert K., Dijk, Gertjan, Reijngoud, Dirk‐Jan, Bakker, Barbara M.

“…Summary Loss of mitochondrial respiratory flux is a hallmark of skeletal muscle aging, contributing to a progressive decline of muscle strength. Endurance…”
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Comprehensive Profiling of Primary and Metastatic ccRCC Reveals a High Homology of the Metastases to a Subregion of the Primary Tumour by Ferronika, Paranita, Hof, Joost, Kats-Ugurlu, Gursah, Sijmons, Rolf H, Terpstra, Martijn M, de Lange, Kim, Leliveld-Kors, Annemarie, Westers, Helga, Kok, Klaas

“…While intratumour genetic heterogeneity of primary clear cell renal cell carcinoma (ccRCC) is well characterized, the genomic profiles of metastatic ccRCCs are…”
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