Search Results - "de Lamballerie, Xavier"

In vitro screening of a FDA approved chemical library reveals potential inhibitors of SARS-CoV-2 replication by Touret, Franck, Gilles, Magali, Barral, Karine, Nougairède, Antoine, van Helden, Jacques, Decroly, Etienne, de Lamballerie, Xavier, Coutard, Bruno

“…A novel coronavirus, named SARS-CoV-2, emerged in 2019 in China and rapidly spread worldwide. As no approved therapeutics exists to treat COVID-19, the disease…”
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Favipiravir antiviral efficacy against SARS-CoV-2 in a hamster model by Driouich, Jean-Sélim, Cochin, Maxime, Lingas, Guillaume, Moureau, Grégory, Touret, Franck, Petit, Paul-Rémi, Piorkowski, Géraldine, Barthélémy, Karine, Laprie, Caroline, Coutard, Bruno, Guedj, Jérémie, de Lamballerie, Xavier, Solas, Caroline, Nougairède, Antoine

“…Despite no or limited pre-clinical evidence, repurposed drugs are massively evaluated in clinical trials to palliate the lack of antiviral molecules against…”
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In vitro evaluation of therapeutic antibodies against a SARS-CoV-2 Omicron B.1.1.529 isolate by Touret, Franck, Baronti, Cécile, Bouzidi, Hawa Sophia, de Lamballerie, Xavier

“…The emergence and rapid spread of the Omicron variant of SARS-CoV-2, which has more than 30 substitutions in the spike glycoprotein, compromises the efficacy…”
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Timing of Antiviral Treatment Initiation is Critical to Reduce SARS‐CoV‐2 Viral Load by Gonçalves, Antonio, Bertrand, Julie, Ke, Ruian, Comets, Emmanuelle, Lamballerie, Xavier, Malvy, Denis, Pizzorno, Andrés, Terrier, Olivier, Rosa Calatrava, Manuel, Mentré, France, Smith, Patrick, Perelson, Alan S., Guedj, Jérémie

“…We modeled the viral dynamics of 13 untreated patients infected with severe acute respiratory syndrome‐coronavirus 2 to infer viral growth parameters and…”
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Favipiravir pharmacokinetics in Ebola-Infected patients of the JIKI trial reveals concentrations lower than targeted by Nguyen, Thi Huyen Tram, Guedj, Jérémie, Anglaret, Xavier, Laouénan, Cédric, Madelain, Vincent, Taburet, Anne-Marie, Baize, Sylvain, Sissoko, Daouda, Pastorino, Boris, Rodallec, Anne, Piorkowski, Géraldine, Carazo, Sara, Conde, Mamoudou N, Gala, Jean-Luc, Bore, Joseph Akoi, Carbonnelle, Caroline, Jacquot, Frédéric, Raoul, Hervé, Malvy, Denis, de Lamballerie, Xavier, Mentré, France

“…In 2014-2015, we assessed favipiravir tolerance and efficacy in patients with Ebola virus (EBOV) disease (EVD) in Guinea (JIKI trial). Because the drug had…”
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Lack of Evidence for Crimean-Congo Hemorrhagic Fever Virus in Ticks Collected from Animals, Corsica, France by Cicculli, Vincent, Maitre, Apolline, Ayhan, Nazli, Mondoloni, Stevan, Paoli, Jean-Christophe, Vial, Laurence, de Lamballerie, Xavier N, Charrel, Remi, Falchi, Alessandra

“…In Corsica, France, 9.1% of livestock serum samples collected during 2014-2016 were found to have antibodies against Crimean-Congo hemorrhagic fever virus…”
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Favipiravir Pharmacokinetics in Nonhuman Primates and Insights for Future Efficacy Studies of Hemorrhagic Fever Viruses by Madelain, Vincent, Guedj, Jérémie, Mentré, France, Nguyen, Thi Huyen Tram, Jacquot, Frédéric, Oestereich, Lisa, Kadota, Takumi, Yamada, Koichi, Taburet, Anne-Marie, de Lamballerie, Xavier, Raoul, Hervé

“…Favipiravir is an RNA polymerase inhibitor that showed strong antiviral efficacy in vitro and in small-animal models of several viruses responsible for…”
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How Did Zika Virus Emerge in the Pacific Islands and Latin America? by Pettersson, John H-O, Eldholm, Vegard, Seligman, Stephen J, Lundkvist, Åke, Falconar, Andrew K, Gaunt, Michael W, Musso, Didier, Nougairède, Antoine, Charrel, Remi, Gould, Ernest A, de Lamballerie, Xavier

“…The unexpected emergence of Zika virus (ZIKV) in the Pacific Islands and Latin America and its association with congenital Zika virus syndrome (CZVS) (which…”
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A novel and sensitive real-time PCR system for universal detection of poxviruses by Luciani, Léa, Inchauste, Lucia, Ferraris, Olivier, Charrel, Rémi, Nougairède, Antoine, Piorkowski, Géraldine, Peyrefitte, Christophe, Bertagnoli, Stéphane, de Lamballerie, Xavier, Priet, Stéphane

“…Success in smallpox eradication was enabled by the absence of non-human reservoir for smallpox virus. However, other poxviruses with a wider host spectrum can…”
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Climate-based models for understanding and forecasting dengue epidemics by Descloux, Elodie, Mangeas, Morgan, Menkes, Christophe Eugène, Lengaigne, Matthieu, Leroy, Anne, Tehei, Temaui, Guillaumot, Laurent, Teurlai, Magali, Gourinat, Ann-Claire, Benzler, Justus, Pfannstiel, Anne, Grangeon, Jean-Paul, Degallier, Nicolas, De Lamballerie, Xavier

“…Dengue dynamics are driven by complex interactions between human-hosts, mosquito-vectors and viruses that are influenced by environmental and climatic factors…”
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Epidemiology of Chikungunya Virus Outbreaks in Guadeloupe and Martinique, 2014: An Observational Study in Volunteer Blood Donors by Gallian, Pierre, Leparc-Goffart, Isabelle, Richard, Pascale, Maire, Françoise, Flusin, Olivier, Djoudi, Rachid, Chiaroni, Jacques, Charrel, Remi, Tiberghien, Pierre, de Lamballerie, Xavier

“…During Dec-2013, a chikungunya virus (CHIKV) outbreak was first detected in the French-West Indies. Subsequently, the virus dispersed to other Caribbean…”
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Concurrent chikungunya and dengue virus infections during simultaneous outbreaks, Gabon, 2007 by Leroy, Eric M, Nkoghe, Dieudoné, Ollomo, Benjamin, Nze-Nkogue, Chimène, Becquart, Pierre, Grard, Gilda, Pourrut, Xavier, Charrel, Rémi, Moureau, Grégory, Ndjoyi-Mbiguino, Angélique, De-Lamballerie, Xavier

“…An outbreak of febrile illness occurred in Gabon in 2007, with 20,000 suspected cases. Chikungunya or dengue-2 virus infections were identified in 321…”
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Metapopulation dynamics of SARS-CoV-2 transmission in a small-scale Amazonian society by Kraft, Thomas S, Seabright, Edmond, Alami, Sarah, Jenness, Samuel M, Hooper, Paul, Beheim, Bret, Davis, Helen, Cummings, Daniel K, Rodriguez, Daniel Eid, Cayuba, Maguin Gutierrez, Miner, Emily, de Lamballerie, Xavier, Inchauste, Lucia, Priet, Stéphane, Trumble, Benjamin C, Stieglitz, Jonathan, Kaplan, Hillard, Gurven, Michael D

“…The severity of infectious disease outbreaks is governed by patterns of human contact, which vary by geography, social organization, mobility, access to…”
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Author Correction: A novel and sensitive real-time PCR system for universal detection of poxviruses by Luciani, Léa, Inchauste, Lucia, Ferraris, Olivier, Charrel, Rémi, Nougairède, Antoine, Piorkowski, Géraldine, Peyrefitte, Christophe, Bertagnoli, Stéphane, de Lamballerie, Xavier, Priet, Stéphane

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Haiku: New paradigm for the reverse genetics of emerging RNA viruses by Atieh, Thérèse, El Ayoubi, Miriam Diala, Aubry, Fabien, Priet, Stéphane, de Lamballerie, Xavier, Nougairède, Antoine

“…Reverse genetics is key technology for producing wild-type and genetically modified viruses. The ISA (Infectious Subgenomic Amplicons) method is a recent…”
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Sandfly-Borne Phlebovirus Isolations from Turkey: New Insight into the Sandfly fever Sicilian and Sandfly fever Naples Species by Alkan, Cigdem, Erisoz Kasap, Ozge, Alten, Bulent, de Lamballerie, Xavier, Charrel, Rémi N

“…Many studies have presented virus sequences which suggest the existence of a variety of putative new phleboviruses transmitted by sandflies in the Old World…”
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Isolation of a novel species of flavivirus and a new strain of Culex flavivirus (Flaviviridae) from a natural mosquito population in Uganda by Cook, Shelley, Moureau, Gregory, Harbach, Ralph E, Mukwaya, Louis, Goodger, Kim, Ssenfuka, Fred, Gould, Ernest, Holmes, Edward C, Lamballerie, Xavier de

“…The genus Flavivirus, which contains approximately 70 single-stranded, positive-sense RNA viruses, represents a unique model for studying the evolution of…”
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Monitoring the proportion of the population infected by SARS-CoV-2 using age-stratified hospitalisation and serological data: a modelling study by Hozé, Nathanaël, Paireau, Juliette, Lapidus, Nathanaël, Tran Kiem, Cécile, Salje, Henrik, Severi, Gianluca, Touvier, Mathilde, Zins, Marie, de Lamballerie, Xavier, Lévy-Bruhl, Daniel, Carrat, Fabrice, Cauchemez, Simon

“…Regional monitoring of the proportion of the population who have been infected by SARS-CoV-2 is important to guide local management of the epidemic, but is…”
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The Crystal Structures of Chikungunya and Venezuelan Equine Encephalitis Virus nsP3 Macro Domains Define a Conserved Adenosine Binding Pocket by MALET, Hélène, COUTARD, Bruno, FERRON, Francois, LESCAR, Julien, GORBALENYA, Alexander E, DE LAMBALLERIE, Xavier, CANARD, Bruno, JAMAL, Said, DUTARTRE, Hélène, PAPAGEORGIOU, Nicolas, NEUVONEN, Maarit, AHOLA, Tero, FORRESTER, Naomi, GOULD, Ernest A, LAFITTE, Daniel

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Random codon re-encoding induces stable reduction of replicative fitness of Chikungunya virus in primate and mosquito cells by Nougairede, Antoine, De Fabritus, Lauriane, Aubry, Fabien, Gould, Ernest A, Holmes, Edward C, de Lamballerie, Xavier

“…Large-scale codon re-encoding represents a powerful method of attenuating viruses to generate safe and cost-effective vaccines. In contrast to specific…”
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