Search Results - "de Lago, E"

A Sativex®‐like combination of phytocannabinoids as a disease‐modifying therapy in a viral model of multiple sclerosis by Feliú, A, Moreno‐Martet, M, Mecha, M, Carrillo‐Salinas, F J, Lago, E, Fernández‐Ruiz, J, Guaza, C

“…Background and Purpose Sativex® is an oromucosal spray, containing equivalent amounts of Δ9‐tetrahydrocannabinol (Δ9‐THC) and cannabidiol (CBD)‐botanical drug…”
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Bankart arthroscopic procedure: comparative study on use of double or single-thread anchors after a 2-year follow-up by Godinho, Glaydson Gomes, Freitas, José Márcio Alves, França, Flávio de Oliveira, de Lago e Santos, Flávio Márcio, Aragão, Alan Arruda, Barros, Marcos Knoll

“…To compare the use of anchors with double and single-thread loading in the single-row Bankart arthroscopic procedure. 252 patients (258 shoulders) underwent…”
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Decreased endocannabinoid levels in the brain and beneficial effects of agents activating cannabinoid and/or vanilloid receptors in a rat model of multiple sclerosis by Cabranes, Ana, Venderova, Katerina, de Lago, Eva, Fezza, Filomena, Sánchez, Antonio, Mestre, Leyre, Valenti, Marta, García-Merino, Antonio, Ramos, José Antonio, Di Marzo, Vincenzo, Fernández-Ruiz, Javier

“…Recent studies have addressed the changes in endocannabinoid ligands and receptors that occur in multiple sclerosis, as a way to explain the efficacy of…”
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Environmental control of Northeast Atlantic mackerel (Scomber scombrus) recruitment in the southern Bay of Biscay: case study of failure in the year 2000 by VILLAMOR, B., GONZALEZ-POLA, C., LAVÍN, A., VALDÉS, L., LAGO DE LANZÓS, A., FRANCO, C., CABANAS, J. M., BERNAL, M., HERNANDEZ, C., IGLESIAS, M., CARRERA, P., PORTEIRO, C.

“…We investigate the effect of strong meteorological perturbations in early spring on the success of mackerel (Scomber scombrus) recruitment in the N/NW Iberian…”
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Egg and larval distributions of seven fish species in north-east Atlantic waters by IBAIBARRIAGA, L., IRIGOIEN, X., SANTOS, M., MOTOS, L., FIVES, J. M., FRANCO, C., LAGO DE LANZÓS, A., ACEVEDO, S., BERNAL, M., BEZ, N., ELTINK, G., FARINHA, A., HAMMER, C., IVERSEN, S. A., MILLIGAN, S. P., REID, D. G.

“…ABSTRACT The distribution of egg and larvae of mackerel, horse mackerel, sardine, hake, megrim, blue whiting and anchovy along the European Atlantic waters…”
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Design, Synthesis, and Biological Evaluation of New Inhibitors of the Endocannabinoid Uptake:  Comparison with Effects on Fatty Acid Amidohydrolase by López-Rodríguez, María L, Viso, Alma, Ortega-Gutiérrez, Silvia, Fowler, Christopher J, Tiger, Gunnar, de Lago, Eva, Fernández-Ruiz, Javier, Ramos, José A

“…A new series of arachidonic acid derivatives were synthesized and evaluated as inhibitors of the endocannabinoid uptake. Most of them are able to inhibit…”
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A Customized System to Test Pelvic Floor Muscles Contraction: A Proof of Concept by Tabbakha, N. E., Bahillo, A., Jimenez-Martin, A., Garcia-Dominguez, J. J., Torralba-de-Lago, E., Torres-Lacomba, M., Navarro-Brazalez, B.

“…Studies show that there is a high prevalence of pelvic floor dysfunctions which negatively affect the quality of life of people who suffer from them. The few…”
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Evaluation of the neuroprotective effect of cannabinoids in a rat model of Parkinson's disease: Importance of antioxidant and cannabinoid receptor-independent properties by García-Arencibia, Moisés, González, Sara, de Lago, Eva, Ramos, José A, Mechoulam, Raphael, Fernández-Ruiz, Javier

“…Abstract We have recently demonstrated that two plant-derived cannabinoids, Δ9 -tetrahydrocannabinol and cannabidiol (CBD), are neuroprotective in an animal…”
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P.2.14 Characterisation of a new model of frontotemporal dementia for neuroprotective studies with cannabinoids by Sanz, I. Santos-García, Cueto, C. Rodriguez, Toscano, L. García, Ruiz, J. Fernández, Femia, E. De Lago

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A S ativex ® ‐like combination of phytocannabinoids as a disease‐modifying therapy in a viral model of multiple sclerosis by Feliú, A, Moreno‐Martet, M, Mecha, M, Carrillo‐Salinas, F J, de Lago, E, Fernández‐Ruiz, J, Guaza, C

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Effect of repeated systemic administration of selective inhibitors of endocannabinoid inactivation on rat brain endocannabinoid levels by de Lago, Eva, Petrosino, Stefania, Valenti, Marta, Morera, Enrico, Ortega-Gutierrez, Silvia, Fernandez-Ruiz, Javier, Di Marzo, Vincenzo

“…Several selective inhibitors of endocannabinoid inactivation via either the fatty acid amide hydrolase (FAAH) or the putative endocannabinoid transporter have…”
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In vivo pharmacological actions of two novel inhibitors of anandamide cellular uptake by de Lago, Eva, Ligresti, Alessia, Ortar, Giorgio, Morera, Enrico, Cabranes, Ana, Pryce, Gareth, Bifulco, Maurizio, Baker, David, Fernandez-Ruiz, Javier, Di Marzo, Vincenzo

“…Two inhibitors of the cellular uptake of the endocannabinoid anandamide, ( R)- N-oleoyl-(1′-hydroxybenzyl)-2′-ethanolamine and ( S)-…”
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Involvement of vanilloid-like receptors in the effects of anandamide on motor behavior and nigrostriatal dopaminergic activity: in vivo and in vitro evidence by de Lago, Eva, de Miguel, Rosario, Lastres-Becker, Isabel, Ramos, José A, Fernández-Ruiz, Javier

“…The administration of the endocannabinoid anandamide to rats produces hypokinesia in parallel to a decrease in the activity of nigrostriatal dopaminergic…”
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UCM707, an inhibitor of the anandamide uptake, behaves as a symptom control agent in models of Huntington's disease and multiple sclerosis, but fails to delay/arrest the progression of different motor-related disorders by de Lago, Eva, Fernández-Ruiz, Javier, Ortega-Gutiérrez, Silvia, Cabranes, Ana, Pryce, Gareth, Baker, David, López-Rodríguez, Mariluz, Ramos, José Antonio

“…To date, UCM707, (5Z,8Z,11Z,14Z)-N-(3-furylmethyl)eicosa-5,8,11,14-tetraenamide, has the highest potency and selectivity in vitro and in vivo as inhibitor of…”
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Effects of inhibition of fatty acid amide hydrolase vs. the anandamide membrane transporter on TRPV1-mediated calcium responses in adult DRG neurons; the role of CB1 receptors by Millns, P. J., Chimenti, M., Ali, N., Ryland, E., De Lago, E., Fernandez-Ruiz, J., Chapman, V., Kendall, D. A.

“…The aim of the present study was to investigate the relationship between TRPV1 stimulation and endocannabinoid‐driven CB1 receptor‐mediated inhibition of…”
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Arvanil, a hybrid endocannabinoid and vanilloid compound, behaves as an antihyperkinetic agent in a rat model of Huntington's disease by de Lago, Eva, Urbani, Paolo, Ramos, José Antonio, Di Marzo, Vincenzo, Fernández-Ruiz, Javier

“…The present study was designed to examine whether arvanil ( N-arachidonoyl-vanillyl-amide), an endocannabinoid/vanilloid structural “hybrid”, might provide…”
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UCM707, a potent and selective inhibitor of endocannabinoid uptake, potentiates hypokinetic and antinociceptive effects of anandamide by de Lago, Eva, Fernández-Ruiz, Javier, Ortega-Gutiérrez, Silvia, Viso, Alma, López-Rodrı́guez, Marı́a Luz, Ramos, José A

“…To date, UCM707, N-(3-furylmethyl)eicosa-5,8,11,14-tetraenamide, has the highest potency and selectivity in vitro as inhibitor of the endocannabinoid…”
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Development of a new sequential injection in-line cloud point extraction system for flame atomic absorption spectrometric determination of manganese in food samples by Lemos, Valfredo Azevedo, Baliza, Patrícia Xavier, de Carvalho, Anaildes Lago, Oliveira, Rafael Vasconcelos, Teixeira, Leonardo Sena Gomes, Bezerra, Marcos Almeida

“…A preconcentration method for manganese determination by sequential injection cloud point extraction with subsequent detection by flame atomic absorption…”
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Effects of inhibition of fatty acid amide hydrolase vs. the anandamide membrane transporter on TRPV1-mediated calcium responses in adult DRG neurons; the role of CB receptors by Millns, P J, Chimenti, M, Ali, N, Ryland, E, de Lago, E, Fernandez-Ruiz, J, Chapman, V, Kendall, D A

“…The aim of the present study was to investigate the relationship between TRPV1 stimulation and endocannabinoid-driven CB(1) receptor-mediated inhibition of…”
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Effects of inhibition of fatty acid amide hydrolase vs. the anandamide membrane transporter on TRPV1‐mediated calcium responses in adult DRG neurons; the role of CB 1 receptors by Millns, P. J., Chimenti, M., Ali, N., Ryland, E., De Lago, E., Fernandez‐Ruiz, J., Chapman, V., Kendall, D. A.

“…The aim of the present study was to investigate the relationship between TRPV1 stimulation and endocannabinoid‐driven CB 1 receptor‐mediated inhibition of…”
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