Search Results - "de Lacoba, Mario Garcia"

Fast H3K9 methylation promoted by CXCL12 contributes to nuclear changes and invasiveness of T-acute lymphoblastic leukemia cells by Madrazo, Elena, González-Novo, Raquel, Ortiz-Placín, Cándido, García de Lacoba, Mario, González-Murillo, África, Ramírez, Manuel, Redondo-Muñoz, Javier

“…T-acute lymphoblastic leukemia (T-ALL) is an aggressive hematological malignancy that comprises the accumulation of malignant T-cells. Despite current…”
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Differential gene expression analysis by RNA-seq reveals the importance of actin cytoskeletal proteins in erythroleukemia cells by Fernández-Calleja, Vanessa, Hernández, Pablo, Schvartzman, Jorge B, García de Lacoba, Mario, Krimer, Dora B

“…Development of drug resistance limits the effectiveness of anticancer treatments. Understanding the molecular mechanisms triggering this event in tumor cells…”
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Versatile Lipases from the Candida rugosa-like Family: A Mechanistic Insight Using Computational Approaches by Rodríguez-Salarichs, Javier, García de Lacoba, Mario, Prieto, Alicia, Martínez, María Jesús, Barriuso, Jorge

“…Lipases are enzymes able to catalyze the hydrolysis or synthesis of triglycerides, depending on the reaction conditions, whereas sterol esterases show the same…”
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Tyrosine aminotransferase from Leishmania infantum: A new drug target candidate by Moreno, Miguel Angel, Alonso, Ana, Alcolea, Pedro Jose, Abramov, Ariel, de Lacoba, Mario García, Abendroth, Jan, Zhang, Sunny, Edwards, Thomas, Lorimer, Don, Myler, Peter John, Larraga, Vicente

“…[Display omitted] •The tyrosine aminotransferase from Leishmania infantum has a cytoplasmic distribution and is able to use the oxoacid ketomethiobutyrate, as…”
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The yefM-yoeB Toxin-Antitoxin Systems of Escherichia coli and Streptococcus pneumoniae: Functional and Structural Correlation by Nieto, Concha, Cherny, Izhack, Khoo, Seok Kooi, de Lacoba, Mario García, Chan, Wai Ting, Yeo, Chew Chieng, Gazit, Ehud, Espinosa, Manuel

“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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The C-terminus of H-Ras as a target for the covalent binding of reactive compounds modulating Ras-dependent pathways by Oeste, Clara L, Díez-Dacal, Beatriz, Bray, Francesca, García de Lacoba, Mario, de la Torre, Beatriz G, Andreu, David, Ruiz-Sánchez, Antonio J, Pérez-Inestrosa, Ezequiel, García-Domínguez, Carlota A, Rojas, José M, Pérez-Sala, Dolores

“…Ras proteins are crucial players in differentiation and oncogenesis and constitute important drug targets. The localization and activity of Ras proteins are…”
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Evolutionarily Distinct Residues in the Uncoupling Protein UCP1 Are Essential for Its Characteristic Basal Proton Conductance by Jiménez-Jiménez, Jesús, Zardoya, Rafael, Ledesma, Amalia, García de Lacoba, Mario, Zaragoza, Pilar, Mar González-Barroso, M., Rial, Eduardo

“…The uncoupling proteins (UCPs) are mitochondrial transporters that modulate the efficiency of oxidative phosphorylation. Members of this family have been…”
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Plasma membrane-associated superstructure: Have we overlooked a new type of organelle in eukaryotic cells? by Rodríguez-Fernández, José Luis, de Lacoba, Mario García

“…A variety of intriguing plasma membrane-associated regions, including focal adhesions, adherens junctions, tight junctions, immunological synapses,…”
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3D environment controls H3K4 methylation and the mechanical response of the nucleus in acute lymphoblastic leukemia cells by González-Novo, Raquel, de Lope-Planelles, Ana, Cruz Rodríguez, María Pilar, González-Murillo, África, Madrazo, Elena, Acitores, David, García de Lacoba, Mario, Ramírez, Manuel, Redondo-Muñoz, Javier

“…Acute lymphoblastic leukemia (ALL) is the most common pediatric cancer, and the infiltration of leukemic cells is critical for disease progression and relapse…”
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Characterization of a pathogenesis-related protein 4 (PR-4) induced in Capsicum chinense L³ plants with dual RNase and DNase activities by Guevara-Morato, Maria Ángeles, de Lacoba, Mario García, García-Luque, Isabel, Serra, Maria Teresa

“…Resistance conferred by the L³ gene is active against most of the tobamoviruses, including the Spanish strain (PMMoV-S), a P₁,₂ pathotype, but not against…”
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5-gene differential expression predicts stability of human intestinal allografts by Talayero, Paloma, Alonso-Guirado, Lola, Padilla, Guillermo, Artaza, Haydee, Dopazo, Ana, Sánchez-Cabo, Fátima, Rodríguez-Muñoz, Sarbelio, Calvo-Pulido, Jorge, Mancebo, Esther, de Lacoba, Mario García, Paz-Artal, Estela

“…In intestinal allografts, endoscopy and histology detect the injury once changes in the bowel wall architecture have occurred. We aimed to identify a molecular…”
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Comparative Analysis of Transcriptomic and Hormonal Responses to Compatible and Incompatible Plant-Virus Interactions that Lead to Cell Death by PACHECO, Remedios, GARCIA-MARCOS, Alberto, MANZANO, Aranzazu, GARCIA DE LACOBA, Mario, CAMANES, Gemma, GARCIA-AGUSTIN, Pilar, RAMON DIAZ-RUIZ, José, TENLLADO, Francisco

“…Hypersensitive response-related programmed cell death (PCD) has been extensively analyzed in various plant-virus interactions. However, little is known about…”
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Putative Porin of Bradyrhizobium sp. (Lupinus) Bacteroids Induced by Glyphosate by de María, Nuria, Guevara, Ángeles, Serra, M. Teresa, García-Luque, Isabel, González-Sama, Alfonso, de Lacoba, Mario García, de Felipe, M. Rosario, Fernández-Pascual, Mercedes

“…Application of glyphosate (N-[phosphonomethyl] glycine) to Bradyrhizobium sp. (Lupinus)-nodulated lupin plants caused modifications in the protein pattern of…”
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Identification of the mitochondrial carrier that provides Yarrowia lipolytica with a fatty acid-induced and nucleotide-sensitive uncoupling protein-like activity by Luévano-Martínez, Luis A., Moyano, Eva, de Lacoba, Mario García, Rial, Eduardo, Uribe-Carvajal, Salvador

“…Uncoupling proteins (UCPs) are mitochondrial carriers distributed throughout the eukaryotic kingdoms. While genes coding for UCPs have been identified in…”
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Nuclear DNA polymerase beta from Leishmania infantum. Cloning, molecular analysis and developmental regulation by Taladriz, S, Hanke, T, Ramiro, M J, García-Díaz, M, García De Lacoba, M, Blanco, L, Larraga, V

“…We have identified a novel polymerase beta (Pol beta)-like enzyme from Leishmania infantum, a parasite protozoon causing disease in humans. This protein, named…”
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Redox regulation of c‐Jun DNA binding by reversible S‐glutathiolation by Klatt, Peter, Molina, Estela Pineda, Lacoba, Mario Garcia, Padilla, C. Alicia, Martínez‐Galisteo, Emilia, Barcena, J., Lamas, Santiago

“…ABSTRACTRedox control of the transcription factor c‐Jun maps to a single cysteine in its DNA binding domain. However, the nature of the oxidized state of this…”
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Features of the Plasmid pMV158-encoded MobM, a Protein Involved in its Mobilization by de Antonio, Carmen, Farı́as, Marı́a Eugenia, de Lacoba, Mario Garcı́a, Espinosa, Manuel

“…The streptococcal promiscuous plasmid pMV158 can be mobilized between a number of bacterial species by means of three elements: (i) the plasmid-encoded…”
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Characterization of a pathogenesis-related protein 4 (PR-4) induced in Capsicum chinense L super(3) plants with dual RNase and DNase activities by Guevara-Morato, Maria Angeles, de Lacoba, Mario Garcia, Garcia-Luque, Isabel, Serra, Maria Teresa

“…Resistance conferred by the L super(3) gene is active against most of the tobamoviruses, including the Spanish strain (PMMoV-S), a P sub(1), sub(2) pathotype,…”
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Modeling the transmembrane arrangement of the uncoupling protein UCP1 and topological considerations of the nucleotide-binding site by Ledesma, Amalia, de Lacoba, Mario García, Arechaga, Ignacio, Rial, Eduardo

“…The uncoupling protein from brown adipose tissue (UCP1) is a mitochondrial proton transporter whose activity is inhibited by purine nucleotides. UCP1, like the…”
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SPO-Seq: An Accessible Method for Efficient Evaluation of Spo11 Catalytic Activity and Profiling Meiotic DSB Hotspots in Saccharomyces cerevisiae by Hernández, Iván, Álvarez-Melo, David, de Lacoba, Mario García, Carballo, Jesús A

“…Meiotic recombination is a key process facilitating the formation of crossovers and the exchange of genetic material between homologous chromosomes in early…”
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