Search Results - "de Kroon, Anton I.P.M"
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Quantitative profiling of PE, MMPE, DMPE, and PC lipid species by multiple precursor ion scanning: A tool for monitoring PE metabolism
Published in Biochimica et biophysica acta (01-12-2011)“…We report a method for the simultaneous identification and quantification of phosphatidylethanolamine (PE), monomethyl-phosphatidylethanolamine (MMPE),…”
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2
Depletion of phosphatidylcholine in yeast induces shortening and increased saturation of the lipid acyl chains: evidence for regulation of intrinsic membrane curvature in a eukaryote
Published in Molecular biology of the cell (01-02-2006)“…To study the consequences of depleting the major membrane phospholipid phosphatidylcholine (PC), exponentially growing cells of a yeast cho2opi3 double…”
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3
Checks and balances in membrane phospholipid class and acyl chain homeostasis, the yeast perspective
Published in Progress in lipid research (01-10-2013)“…Glycerophospholipids are the most abundant membrane lipid constituents in most eukaryotic cells. As a consequence, phospholipid class and acyl chain…”
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4
Ligation Strategies for Targeting Liposomal Nanocarriers
Published in BioMed research international (01-01-2014)“…Liposomes have been exploited for pharmaceutical purposes, including diagnostic imaging and drug and gene delivery. The versatility of liposomes as drug…”
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5
Phospholipid composition of highly purified mitochondrial outer membranes of rat liver and Neurospora crassa. Is cardiolipin present in the mitochondrial outer membrane?
Published in Biochimica et biophysica acta (03-04-1997)“…Isolated mitochondrial outer membrane vesicles (OMV) are a suitable system for studying various functions of the mitochondrial outer membrane. For studies on…”
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6
Antitumor activity and biodistribution of cisplatin nanocapsules in nude mice bearing human ovarian carcinoma xenografts
Published in Anti-cancer drugs (01-08-2008)“…Cisplatin nanocapsules represent a novel lipid formulation of the anticancer drug cis-diamminedichloridoplatinum(II) (cisplatin), characterized by an…”
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7
E. coli MG1655 modulates its phospholipid composition through the cell cycle
Published in FEBS letters (14-09-2015)“…[Display omitted] •The phospholipid fraction of the B and D periods of E. coli MG1655 was profiled.•The PG fraction increases rapidly relative to other PLs…”
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Metabolism of phosphatidylcholine and its implications for lipid acyl chain composition in Saccharomyces cerevisiae
Published in Biochimica et biophysica acta (01-03-2007)“…Phosphatidylcholine (PC) is a very abundant membrane lipid in most eukaryotes including the model organism Saccharomyces cerevisiae. Consequently, the…”
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9
Phospholipid flip-flop in biogenic membranes: what is needed to connect opposite sides
Published in Seminars in cell & developmental biology (01-06-2002)“…Phospholipids are synthesized in biogenic membranes, but only on one leaflet of the bilayer. To support balanced growth of the membrane, phospholipid…”
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Yeast cells accumulate excess endogenous palmitate in phosphatidylcholine by acyl chain remodeling involving the phospholipase B Plb1p
Published in Biochimica et biophysica acta (01-06-2013)“…In the yeast Saccharomyces cerevisiae, the molecular species profile of the major membrane glycerophospholipid phosphatidylcholine (PC) is determined by the…”
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11
In Vivo Assessment of Thermosensitive Liposomes for the Treatment of Port Wine Stains by Antifibrinolytic Site-Specific Pharmaco-Laser Therapy
Published in Pharmaceutics (25-06-2020)“…Antifibrinolytic site-specific pharmaco-laser therapy (SSPLT) is an experimental treatment modality for refractory port wine stains (PWS). Conceptually,…”
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12
Topology and transport of membrane lipids in bacteria
Published in Biochimica et biophysica acta (10-03-2000)“…The last two decades have witnessed a break-through in identifying and understanding the functions of both the proteins and lipids of bacterial membranes. This…”
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13
High Cytotoxicity of Cisplatin Nanocapsules in Ovarian Carcinoma Cells Depends on Uptake by Caveolae-Mediated Endocytosis
Published in Clinical cancer research (15-02-2009)“…Purpose: Cisplatin nanocapsules, nanoprecipitates of cisplatin encapsulated in phospholipid bilayers, exhibit increased in vitro toxicity compared with the…”
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14
Lipid Acyl Chain Remodeling in Yeast
Published in Lipid Insights (2015)“…Membrane lipid homeostasis is maintained by de novo synthesis, intracellular transport, remodeling, and degradation of lipid molecules. Glycerophospholipids,…”
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Carboplatin nanocapsules: a highly cytotoxic, phospholipid-based formulation of carboplatin
Published in Molecular cancer therapeutics (01-08-2006)“…Platinum-based drugs are widely used in cancer chemotherapy. However, their clinical use is limited by systemic toxicity, rapid blood clearance, and the…”
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16
Translocation of Phospholipids Is Facilitated by a Subset of Membrane-spanning Proteins of the Bacterial Cytoplasmic Membrane
Published in The Journal of biological chemistry (04-07-2003)“…The mechanism by which phospholipids are transported across biogenic membranes, such as the bacterial cytoplasmic membrane, is unknown. We hypothesized that…”
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Apocytochrome c requires the TOM complex for translocation across the mitochondrial outer membrane
Published in The EMBO journal (15-10-2001)“…The import of proteins into the mitochondrial intermembrane space differs in various aspects from the classical import pathway into the matrix. Apocytochrome c…”
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18
Impaired cisplatin influx in an A2780 mutant cell line: Evidence for a putative, cis-configuration-specific, platinum influx transporter
Published in Cancer biology & therapy (01-08-2006)“…The effectiveness of platinum drugs in the treatment of cancer is hindered by intrinsic and acquired resistance. The cause of clinical resistance to platinum…”
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19
The selective utilization of substrates in vivo by the phosphatidylethanolamine and phosphatidylcholine biosynthetic enzymes Ept1p and Cpt1p in yeast
Published in FEBS letters (02-07-2004)“…In yeast, the aminoalcohol phosphotransferases Ept1p and Cpt1p catalyze the final steps in the CDP-ethanolamine and CDP-choline routes leading to…”
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20
Lipid map of the mammalian cell
Published in Journal of cell science (01-01-2011)Get full text
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