Search Results - "de Kleijn, Ester D"

Circulating nucleosomes and severity of illness in children suffering from meningococcal sepsis treated with protein C by Zeerleder, Sacha, Stephan, Femke, Emonts, Marieke, de Kleijn, Ester D, Esmon, Charles T, Varadi, Katalin, Hack, Cornelis Erik, Hazelzet, Jan A

“…OBJECTIVE:Cell death leading to circulating nucleosomes and histones is a critical step in the pathogenesis of sepsis and contributes to lethality. Activated…”
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Activation of protein C following infusion of protein C concentrate in children with severe meningococcal sepsis and purpura fulminans: A randomized, double-blinded, placebo-controlled, dose-finding study by de Kleijn, Ester D, de Groot, Ronald, Hack, C Erik, H. Mulder, Paul G, Engl, Werner, Moritz, Berta, Joosten, Koen F. M, Hazelzet, Jan A

“…BACKGROUNDMeningococcal septic shock in children results in high mortality and morbidity, and decreased protein C levels in these patients are associated with…”
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Serum lipids and disease severity in children with severe meningococcal sepsis by Vermont, Clementien L, den Brinker, Marieke, Kâkeci, Nimet, de Kleijn, Ester D, de Rijke, Yolanda B, Joosten, Koen F. M, de Groot, Ronald, Hazelzet, Jan A

“…OBJECTIVE:To evaluate the role of cholesterol and lipoproteins in children with severe meningococcal sepsis. DESIGN:Retrospective observational study…”
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Prevention of Meningococcal Serogroup B Infections in Children: A Protein-Based Vaccine Induces Immunologic Memory by de Kleijn, Ester D., de Groot, Ronald, Lafeber, Arianne B., Labadie, Jerry, van Limpt, Cees J. P., Visser, John, Berbers, Guy A. M., van Alphen, Loek, Rümke, Hans C

“…Immunologic memory against meningococci was studied in 177 children (100 children were 10–11 years old and 77 were 5–6 years old) 2.5 years after vaccination…”
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CC and CXC chemokine levels in children with meningococcal sepsis accurately predict mortality and disease severity by Vermont, Clementien L, Hazelzet, Jan A, de Kleijn, Ester D, van den Dobbelsteen, Germie P J M, de Groot, Ronald

“…Chemokines are a superfamily of small peptides involved in leukocyte chemotaxis and in the induction of cytokines in a wide range of infectious diseases…”
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Immunogenicity and safety of a hexavalent meningococcal outer-membrane-vesicle vaccine in children of 2–3 and 7–8 years of age by de Kleijn, Ester D, de Groot, Ronald, Labadie, Jerry, Lafeber, Arianne B, van den Dobbelsteen, Germie, van Alphen, Loek, van Dijken, Harry, Kuipers, Betsy, van Omme, Gijs-Willem, Wala, Mayke, Juttmann, Ricardo, Rümke, Hans C

“…To study the reactogenicity and immunogenicity of a hexavalent meningococcal outer-membrane-vesicle vaccine (OMV), two different dosages of this vaccine (7.5…”
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Low serum cortisol in combination with high adrenocorticotrophic hormone concentrations are associated with poor outcome in children with severe meningococcal disease by DE KLEIJN, ESTER D, JOOSTEN, KOEN F. M, VAN RIJN, BOUKJE, WESTERTERP, MARINKE, DE GROOT, RONALD, HOKKEN-KOELEGA, ANITA C. S, HAZELZET, JAN A

“…OBJECTIVES.To study the correlation between serum concentrations of adrenocorticotrophic hormone (ACTH) and cortisol in relation to severity of disease in…”
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Endothelial Protein C Activation in Meningococcal Sepsis by Piette, W W, Lentz, S R

“…To the Editor: In the August 9 issue, Faust et al. 1 reported that the level of endothelial expression of thrombomodulin and the endothelial protein C receptor…”
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Immunogenicity and safety of monovalent p1.7(h),4 meningococcal outer membrane vesicle vaccine in toddlers: comparison of two vaccination schedules and two vaccine formulations by de Kleijn, E D, de Groot, R, Lafeber, A B, Labadie, J, van Limpt, K C, Visser, J, Berbers, G A, van Alphen, L, Rümke, H C

“…The safety and immunogenicity of two PorA-based meningococcal outer membrane vesicle (OMV) vaccines against the P1.4 serosubtype adsorbed with AlPO(4) or…”
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Immunogenicity and safety of monovalent P1.7 h,4 meningococcal outer membrane vesicle vaccine in toddlers: comparison of two vaccination schedules and two vaccine formulations by de Kleijn, Ester D., de Groot, Ronald, Lafeber, Arianne B., Labadie, Jerry, van Limpt, Kees C.J.P., Visser, John, Berbers, Guy A.M., van Alphen, Loek, Rümke, Hans C.

“…The safety and immunogenicity of two PorA-based meningococcal outer membrane vesicle (OMV) vaccines against the P1.4 serosubtype adsorbed with AlPO 4 or Al(OH)…”
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Immunogenicity and safety of monovalent P1.7h, 4 meningococcal outer membrane vesicle vaccine in toddlers : comparison of two vaccination schedules and two vaccine formulations by DE KLEIJN, Ester D, DE GROOT, Ronald, LAFEBER, Arianne B, LABADIE, Jerry, VAN LIMPT, Kees C. J. P, VISSER, John, BERBERS, Guy A. M, VAN ALPHEN, Loek, RÜMKE, Hans C

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