Search Results - "de Kleer, I"

Lactic acid bacteria differ in their ability to induce functional regulatory T cells in humans by De Roock, S., Van Elk, M., Van Dijk, M. E. A., Timmerman, H. M., Rijkers, G. T., Prakken, B. J., Hoekstra, M. O., De Kleer, I. M.

“…Summary Background Trials with probiotic lactic acid bacteria have yielded different results, which may be due to the strains used. Lactobacilli and…”
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Autologous stem cell transplantation for refractory juvenile idiopathic arthritis: analysis of clinical effects, mortality, and transplant related morbidity by de Kleer, I M, Brinkman, D M C, Ferster, A, Abinun, M, Quartier, P, van der Net, J, ten Cate, R, Wedderburn, L R, Horneff, G, Oppermann, J, Zintl, F, Foster, H E, Prieur, A M, Fasth, A, van Rossum, M A J, Kuis, W, Wulffraat, N M

“…Objective: To evaluate the safety and efficacy of autologous stem cell transplantation (ASCT) for refractory juvenile idiopathic arthritis (JIA). Design:…”
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Stem cell source-dependent reconstitution of FOXP3+ T cells after pediatric SCT and the association with allo-reactive disease by Reubsaet, L L, de Pagter, A P J, van Baarle, D, Keukens, L, Nanlohy, N, Sanders, E A M, Prakken, B J, Boelens, J J, de Kleer, I M

“…In adult patients, regulatory CD4+FOXP3+ T cells are suggested to have a role in the control of allo-reactive disease after hematopoietic SCT (HSCT). We…”
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Myeloid related protein 8 and 14 secretion reflects phagocyte activation and correlates with disease activity in juvenile idiopathic arthritis treated with autologous stem cell transplantation by Wulffraat, N M, Haas, P J, Frosch, M, de Kleer, I M, Vogl, T, Brinkman, D M C, Quartier, P, Roth, J, Kuis, W

“…Objectives: To determine whether myeloid related proteins (MRP8/MRP14), a complex of two S100 proteins related to neutrophil and monocyte activation, might be…”
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Long-term follow-up of autologous stem cell transplantation for refractory juvenile idiopathic arthritis by Wulffraat, N M, Brinkman, D, Ferster, A, Opperman, J, ten Cate, R, Wedderburn, L, Foster, H, Abinun, M, Prieur, A M, Horneff, G, Zintl, F, de Kleer, I, Kuis, W

“…Since 1997, autologous stem cell transplantation (ASCT) had been applied to more than 40 children with polyarticular or systemic juvenile idiopathic arthritis…”
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Severe acute respiratory infection caused by swine influenza virus in a child necessitating extracorporeal membrane oxygenation (ECMO), the Netherlands, October 2016 by Fraaij, Pieter L A, Wildschut, Enno D, Houmes, Robert J, Swaan, Corien M, Hoebe, Christian J, de Jonge, H C C, Tolsma, Paulien, de Kleer, Isme, Pas, Suzan D, Oude Munnink, Bas B, Phan, My V T, Bestebroer, Theo M, Roosenhoff, R Shanty, van Kampen, Jeroen J A, Cotten, Matthew, Beerens, Nancy, Fouchier, Ron A M, van den Kerkhof, Johannes H, Timen, Aura, Koopmans, Marion P

“…In October 2016, a severe infection with swine influenza A(H1N1) virus of the Eurasian avian lineage occurred in a child with a previous history of eczema in…”
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Lung function abnormalities and respiratory muscle weakness in children with juvenile chronic arthritis by Knook, LM, de Kleer, IM, van der Ent, CK, van der Net, JJ, Prakken, BJ, Kuis, W

“…In contrast to adult rheumatoid arthritis (RA) little is known about the prevalence, nature and cause of lung function abnormalities in children with juvenile…”
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Regulatory T cells in autologous stem cell transplantation for autoimmune disease by van Wijk, F., Roord, S. T., Vastert, B., de Kleer, I, Wulffraat, N., Prakken, B. J.

“…Since a decade autologous stem cell transplantation (ASCT) is successfully performed to treat patients with severe autoimmune disease. However, the mechanism…”
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The spontaneous remission of juvenile idiopathic arthritis is characterized by CD30+ T cells directed to human heat‐shock protein 60 capable of producing the regulatory cytokine interleukin‐10 by de Kleer, I. M., Kamphuis, S. M., Rijkers, G. T., Scholtens, L., Gordon, G., de Jager, W., Häfner, R., van de Zee, R., van Eden, W., Kuis, W., Prakken, B. J.

“…Objective To test the hypothesis that T cell reactivity to self heat‐shock protein 60 (Hsp60) in patients with remitting juvenile idiopathic arthritis (JIA) is…”
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Autologous stem cell transplantation in children with severe progressive systemic or polyarticular juvenile idiopathic arthritis: Long‐term followup of a prospective clinical trial by Brinkman, D. M. C., de Kleer, I. M., ten Cate, R., van Rossum, M. A. J., Bekkering, W. P., Fasth, A., van Tol, M. J. D., Kuis, W., Wulffraat, N. M., Vossen, J. M.

“…Objective To assess the safety and efficacy of intensive immunosuppression followed by T cell–depleted autologous hematopoietic stem cell transplantation…”
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T-Cell reactivity to human HSP60 in oligo-articular juvenile chronic arthritis is associated with a favorable prognosis and the generation of regulatory cytokines in the inflamed joint by Prakken, A.B.J, van Hoeij, M.J.W, Kuis, W, Kavelaars, A, Heynen, C.J, Scholtens, E, de Kleer, I.M, Rijkers, G.T, van Eden, W

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Heat shock protein 60 reactive T cells in juvenile idiopathic arthritis: what is new? by VERCOULEN, Yvonne, VAN TEIJLINGEN, Nienke H, DE KLEER, Ismé M, KAMPHUIS, Sylvia, ALBANI, Salvatore, PRAKKEN, Berent J

“…Juvenile idiopathic arthritis (JIA) is a disease characterized by chronic joint inflammation, caused by a deregulated immune response. In patients with JIA,…”
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Autologous stem cell transplantation for refractory juvenile idiopathic artrhitis: current results and perspectives by Wulffraat, M, de Kleer, I, Brinkman, D, ten Cate, R, van der Net, J.J, Rijkers, G.T, Kuis, W

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V1.2. RECOGNITION OF MULTIPLE HSP60 EPITOPES IN PATIENTS WITH JUVENILE IDIOPATHIC ARTHRITIS OPENS THE WAY FOR ANTIGEN-SPECIFIC IMMUNOTHERAPY by Kamphuis, S. S. M., de Jager, W., de Kleer, I. M., Gordon, G., Koffeman, E., Massa, M., Martini, A., Rijkers, G.T., van Eden, W., Kuis, W., Prakken, A. B. J., Albani, S.

“…[...]there are functionally significant allelic associations between -174, -572 and -598 polymorphisms of IL-6, but only -174 and -572 exert independent…”
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Autologous stem cell transplantation for autoimmunity induces immunologic self-tolerance by reprogramming autoreactive T cells and restoring the CD4+CD25+ immune regulatory network by de Kleer, Ismé, Vastert, Bas, Klein, Mark, Teklenburg, Gijs, Arkesteijn, Ger, Yung, Gisella Puga, Albani, Salvo, Kuis, Wietse, Wulffraat, Nico, Prakken, Berent

“…Despite a rapidly accumulating clinical experience with autologous stem cell transplantation (ASCT) as a treatment for severe refractory autoimmune disease,…”
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V1.2. RECOGNITION OF MULTIPLE HSP60 EPITOPES IN PATIENTS WITH JUVENILE IDIOPATHIC ARTHRITIS OPENS THE WAY FOR ANTIGEN-SPECIFIC IMMUNOTHERAPYV1.3. HUMAN HSP60 INDUCES REGULATORY T CELLS EXPRESSING CD30 IN THE REMITTING FORM OF JIAV1.4. FUNCTIONALlY SIGNIFICANT IL-6 ALLELIC ASSOCIATIONS IN SYSTEMIC JUVENILE IDIOPATHIC ARTHRITIS (SJIA)V1.5. STUDY OF THE INSULIN-LIKE GROWTH FACTOR-I (IGF-I) SYSTEM IN INTERLEUKIN-6 (IL-6) TRANSGENIC MICEV1.6. A NOVEL 5' FLANKING REGION POLYMORPHISM OF MACROPHAGE MIGR by Kamphuis, S. S. M., de Kleer, I., Jeffery, R., Meazza, C., Donn, R. P., Cimaz, R., Ruperto, N., Davies, K., Gardner-Medwin, J. M., Seeliger, S., Vargova, V., Vesely, R., Ravelli, A., van Rossum, M. A. J., Simonini, G., Tsitsami, E., Kanakoudi-Tsakalidou, F., De Kleer, I., Lovell, D. J., Martini, G., Hagelberg, S., Fazeelat, B., Lehmann, H. W., Lahdenne, P., Brik, R., Frenkel, J., Ozdogan, H., Berglind-Dehlin, G., Custers, J. W. H., Bekkering, W. P., Maillard, S. M., Takken, T., Scott, J. M., de Jager, W., de Kleer, I. M., Gordon, G., Koffeman, E., Massa, M., Martini, A., Rijkers, G.T., van Eden, W., Kuis, W., Prakken, A. B. J., Albani, S., Kamphuis, S., Wulffraat, N., van der Zee, R., Rijkers, G., Prakken, B., Luong, L., Ogilvie, E., MacFadyen, J., Humphries, S., Woo, P., Pignatti, P., Vivarelli, M., Garrone, S., Barreca, A, Martini, A, De Benedetti, F., Shelley, E., Ollier, W., Thomson, W., Meroni, P. L., Brucato, A., Catelli, L., Goulene, K., Stramba-Badiale, M., Ravelli, Murray, Gianni, Lovell, Tsitsami, Feldman, Silverman, Machado, Garay, Andersson-Gare, De Cunto, Dolezalova, Hashkes, Honkanen, Huppertz, Joos, Kuis, Lilleby, Melo-Gomes, Ozdogan, Prieur, Rumba, Susic, Woo, Martini, Ramanan, A. V., Sawhney, S., Murray, K. J., Dolezalova, P., Southwood, T. R., Ryder, C. A. J., Engels, I. H.

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Epitope-Specific Immunotherapy Induces Immune Deviation of Proinflammatory T Cells in Rheumatoid Arthritis by Prakken, Berent J., Samodal, Rodrigo, Le, Tho D., Giannoni, Francesca, Yung, Gisella Puga, Scavulli, John, Amox, Diane, Roord, Sarah, de Kleer, Isme, Bonnin, Dustan, Lanza, Paola, Berry, Charles, Massa, Margherita, Billetta, Rosario, Albani, Salvatore, Carson, Dennis A.

“…Modulation of epitope-specific immune responses would represent a major addition to available therapeutic options for many autoimmune diseases. The objective…”
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CD30 discriminates heat shock protein 60-induced FOXP3+ CD4+ T cells with a regulatory phenotype by de Kleer, Ismé, Vercoulen, Yvonne, Klein, Mark, Meerding, Jenny, Albani, Salvatore, van der Zee, Ruurd, Sawitzki, Birgit, Hamann, Alf, Kuis, Wietse, Prakken, Berent

“…In many animal models, the manifestations of inflammatory diseases can be prevented by the adoptive transfer of CD4(+)FOXP3(+) regulatory T cells (Tregs)…”
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Autoimmunity or immune deficiency? On the role and function of regulatory T cells in chronic arthritis by Prakken, BJ, de Kleer, I

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Autologous stem cell transplantation in children with severe progressive systemic or polyarticular juvenile idiopathic arthritis: long-term follow-up of a prospective clinical trial by Brinkman, D M C, de Kleer, I M, ten Cate, R, van Rossum, M A J, Bekkering, W P, Fasth, A, van Tol, M J D, Kuis, W, Wulffraat, N M, Vossen, J M

“…To assess the safety and efficacy of intensive immunosuppression followed by T cell-depleted autologous hematopoietic stem cell transplantation (ASCT) for…”
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