Search Results - "de Keczer, Steve A"

An integrative genomic analysis identifies Bhmt2 as a diet-dependent genetic factor protecting against acetaminophen-induced liver toxicity by Liu, Hong-Hsing, Lu, Peng, Guo, Yingying, Farrell, Erin, Zhang, Xun, Zheng, Ming, Bosano, Betty, Zhang, Zhaomei, Allard, John, Liao, Guochun, Fu, Siyu, Chen, Jinzhi, Dolim, Kimberly, Kuroda, Ayako, Usuka, Jonathan, Cheng, Janet, Tao, William, Welch, Kevin, Liu, Yanzhou, Pease, Joseph, de Keczer, Steve A, Masjedizadeh, Mohammad, Hu, Jing-Shan, Weller, Paul, Garrow, Tim, Peltz, Gary

“…Acetaminophen-induced liver toxicity is the most frequent precipitating cause of acute liver failure and liver transplant, but contemporary medical practice…”
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Simple single-step single-enzyme synthesis of [14C]-GSH by de Keczer, Steve A., Voronin, Tatyana, Yao, Jennifer, Zhang, Fang-Jie, Masjedizadeh, Mohammad R.

“…The tri‐peptide [14C]‐glutathione ([14C]‐GSH) was synthesized in a single step by GSH synthetase catalyzed reaction of L‐γ‐glutamyl‐L‐cysteine and…”
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High specific activity tritium labeling of vitamin D derivative RO275646 by de Keczer, Steve A., Lane, Tim S., Voronin, Tatyana, Masjedizadeh, Mohammad R.

“…The octahydroindenone intermediate was tritium labeled using T2O isotope exchange labeling, and then elaborated to the vitamin D derivative RO275646. Though…”
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M+4 stable isotope labeling of levovirin and M+7 and carbon-14 labeling of levovirin valinate pro-drug by de Keczer, Steve A., Masjedizadeh, Mohammad R., Wu, Shao-Yong, Lara-Jaime, Teresa, Comstock, Kate, Dvorak, Charles, Liu, Yu-Ying, Berger, Walter

“…[M+4]‐labeled levovirin 5 (231 mg) was synthesized as an MS reference compound from [M+4] triazole ester 2. [M+7]‐labeled levovirin valinate 6 (127 mg) was…”
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Uncatalyzed microwave deuterium exchange labeling of bleomycin A2 by de Keczer, Steve A., Lane, Tim S., Masjedizadeh, Mohammad R.

“…Bleomycin sulfate in D2O was deuterated using microwave irradiation under catalyst free conditions. Following the removal of labile deuterium and purification,…”
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Uncatalyzed microwave deuterium exchange labeling of bleomycin A 2 by de Keczer, Steve A., Lane, Tim S., Masjedizadeh, Mohammad R.

“…Bleomycin sulfate in D 2 O was deuterated using microwave irradiation under catalyst free conditions. Following the removal of labile deuterium and…”
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Adsorption losses from urine-based cannabinoid calibrators during routine use by Blanc, J A, Manneh, V A, Ernst, R, Berger, D E, de Keczer, S A, Chase, C, Centofanti, J M, DeLizza, A J

“…The major metabolite of cannabis found in urine, 11-nor-delta 9-tetrahydrocannabinol-9-carboxylic acid (delta 9-THC), is the compound most often used to…”
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